Review: taking Seroquel and Depakote together


Summary

Drug interactions are reported among people who take Seroquel and Depakote together. This review analyzes the effectiveness and drug interactions between Seroquel and Depakote. It is created by eHealthMe based on reports of 6,260 people who take the same drugs from FDA and social media, and is updated regularly.

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Seroquel

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. (latest outcomes from Seroquel 89,715 users)

Depakote

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. (latest outcomes from Depakote 38,407 users)

On Sep, 20, 2016

6,260 people who take Seroquel, Depakote are studied.


Number of reports submitted per year:

Seroquel and Depakote drug interactions.

Drug effectiveness over time:

Seroquel:
  • < 1 month: 42.0% - (9 of 21 people)
  • 1 - 6 months: 26.0% - (8 of 30 people)
  • 6 - 12 months: 40.0% - (6 of 15 people)
  • 1 - 2 years: 35.0% - (7 of 20 people)
  • 2 - 5 years: 36.0% - (9 of 25 people)
  • 5 - 10 years: 75.0% - (9 of 12 people)
  • 10+ years: 40.0% - (2 of 5 people)
  • not specified: 66.0% - (2 of 3 people)
Depakote:
  • < 1 month: 21.0% - (4 of 19 people)
  • 1 - 6 months: 24.0% - (7 of 29 people)
  • 6 - 12 months: 35.0% - (5 of 14 people)
  • 1 - 2 years: 38.0% - (5 of 13 people)
  • 2 - 5 years: 30.0% - (9 of 30 people)
  • 5 - 10 years: 83.0% - (10 of 12 people)
  • 10+ years: 33.0% - (4 of 12 people)
  • not specified: 50.0% - (1 of 2 people)

Drug effectiveness by gender:

Seroquel:
  • female: 45.0% - (29 of 64 people)
  • male: 34.0% - (23 of 67 people)
Depakote:
  • female: 38.0% - (26 of 67 people)
  • male: 29.0% - (19 of 64 people)

Drug effectiveness by age:

Seroquel:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 1 people)
  • 10-19: 15.0% - (3 of 20 people)
  • 20-29: 53.0% - (14 of 26 people)
  • 30-39: 46.0% - (14 of 30 people)
  • 40-49: 54.0% - (13 of 24 people)
  • 50-59: 38.0% - (7 of 18 people)
  • 60+: 8.0% - (1 of 12 people)
Depakote:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 1 people)
  • 10-19: 15.0% - (3 of 20 people)
  • 20-29: 45.0% - (11 of 24 people)
  • 30-39: 46.0% - (14 of 30 people)
  • 40-49: 24.0% - (6 of 25 people)
  • 50-59: 50.0% - (9 of 18 people)
  • 60+: 15.0% - (2 of 13 people)

Most common drug interactions over time *:

< 1 month:
  • diabetes mellitus
  • type 2 diabetes mellitus
  • somnolence
  • depression
  • weight increased
  • suicidal ideation
  • aggression
  • mania
  • vomiting
  • loss of consciousness
1 - 6 months:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • blood cholesterol increased
  • weight increased
  • neuropathy peripheral
  • chest pain
  • diabetes mellitus inadequate control
  • blood triglycerides increased
  • vision blurred
  • depression
6 - 12 months:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • weight increased
  • obesity
  • blood cholesterol increased
  • neuropathy peripheral
  • diabetes mellitus inadequate control
  • hyperglycaemia
  • thrombosis
  • diabetic ketoacidosis
1 - 2 years:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • blood cholesterol increased
  • hyperglycaemia
  • obesity
  • diabetes mellitus inadequate control
  • hyperlipidaemia
  • neuropathy peripheral
  • weight increased
  • blood triglycerides increased
2 - 5 years:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • blood cholesterol increased
  • obesity
  • diabetes mellitus inadequate control
  • diabetic neuropathy
  • blood triglycerides increased
  • hyperglycaemia
  • neuropathy peripheral
  • hyperlipidaemia
5 - 10 years:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • blood cholesterol increased
  • obesity
  • hyperglycaemia
  • diabetes mellitus inadequate control
  • hyperlipidaemia
  • blood triglycerides increased
  • neuropathy peripheral
  • diabetic neuropathy
10+ years:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • obesity
  • renal failure
  • convulsion
  • neuropathy peripheral
  • diabetes mellitus inadequate control
  • diabetic neuropathy
  • insomnia
  • diabetic nephropathy
not specified:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • insomnia
  • weight increased
  • depression
  • somnolence
  • blood cholesterol increased
  • fall
  • fatigue
  • drug ineffective

Most common drug interactions by gender *:

female:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • insomnia
  • blood cholesterol increased
  • depression
  • weight increased
  • fall
  • somnolence
  • tremor
  • malaise
male:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • weight increased
  • insomnia
  • diabetes mellitus inadequate control
  • blood cholesterol increased
  • neuropathy peripheral
  • diabetic neuropathy
  • depression
  • obesity

Most common drug interactions by age *:

0-1:
  • convulsion
  • pancreatitis
  • diabetes mellitus
  • type 2 diabetes mellitus
  • neutropenia
  • thrombocytopenia
  • anaemia
  • cerebrovascular accident
  • hyperlipidaemia
  • type 1 diabetes mellitus
2-9:
  • hyperglycaemia
  • overdose
  • arrhythmia
  • drug ineffective
  • weight increased
  • convulsion
  • suicidal ideation
  • tardive dyskinesia
  • obesity
  • aggression
10-19:
  • type 2 diabetes mellitus
  • type 1 diabetes mellitus
  • abnormal behaviour
  • diabetes mellitus
  • weight increased
  • diabetic ketoacidosis
  • suicidal ideation
  • blood triglycerides increased
  • hyperglycaemia
  • aggression
20-29:
  • diabetes mellitus
  • type 2 diabetes mellitus
  • weight increased
  • blood cholesterol increased
  • suicidal ideation
  • diabetic ketoacidosis
  • blood triglycerides increased
  • obesity
  • pancreatitis
  • suicide attempt
30-39:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • blood cholesterol increased
  • obesity
  • weight increased
  • diabetes mellitus inadequate control
  • pancreatitis
  • diabetic neuropathy
  • hyperglycaemia
  • diabetic ketoacidosis
40-49:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • blood cholesterol increased
  • neuropathy peripheral
  • diabetes mellitus inadequate control
  • blood triglycerides increased
  • diabetic neuropathy
  • hyperlipidaemia
  • chest pain
  • obesity
50-59:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • insomnia
  • fall
  • depression
  • bipolar disorder
  • weight decreased
  • feeling abnormal
  • convulsion
  • somnolence
60+:
  • diabetes mellitus
  • insomnia
  • weight increased
  • gait disturbance
  • fatigue
  • type 2 diabetes mellitus
  • pain in extremity
  • malaise
  • confusional state
  • somnolence

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Seroquel and Depakote?

Can you answer these questions?

More questions for: Seroquel, Depakote

You may be interested in these reviews

More reviews for: Seroquel, Depakote

On eHealthMe, Seroquel (quetiapine fumarate) is often used to treat bipolar disorder. Depakote (divalproex sodium) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.