Review: taking Singulair and Loratadine together


Summary

Drug interactions are reported among people who take Singulair and Loratadine together. This review analyzes the effectiveness and drug interactions between Singulair and Loratadine. It is created by eHealthMe based on reports of 2,820 people who take the same drugs from FDA and social media, and is updated regularly.

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Singulair

Singulair has active ingredients of montelukast sodium. It is often used in asthma. (latest outcomes from Singulair 49,741 users)

Loratadine

Loratadine has active ingredients of loratadine. It is often used in hypersensitivity. (latest outcomes from Loratadine 12,984 users)

On Aug, 25, 2016

2,820 people who take Singulair, Loratadine are studied.


Number of reports submitted per year:

Singulair and Loratadine drug interactions.

Drug effectiveness over time:

Singulair:
  • < 1 month: 23.0% - (3 of 13 people)
  • 1 - 6 months: 18.0% - (3 of 16 people)
  • 6 - 12 months: 37.0% - (3 of 8 people)
  • 1 - 2 years: 38.0% - (7 of 18 people)
  • 2 - 5 years: 51.0% - (14 of 27 people)
  • 5 - 10 years: 66.0% - (12 of 18 people)
  • 10+ years: 50.0% - (8 of 16 people)
  • not specified: 0.0% - (0 of 0 people)
Loratadine:
  • < 1 month: 8.0% - (1 of 12 people)
  • 1 - 6 months: 20.0% - (3 of 15 people)
  • 6 - 12 months: 37.0% - (3 of 8 people)
  • 1 - 2 years: 7.0% - (1 of 13 people)
  • 2 - 5 years: 39.0% - (13 of 33 people)
  • 5 - 10 years: 33.0% - (7 of 21 people)
  • 10+ years: 50.0% - (7 of 14 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Singulair:
  • female: 46.0% - (35 of 76 people)
  • male: 37.0% - (15 of 40 people)
Loratadine:
  • female: 35.0% - (28 of 78 people)
  • male: 18.0% - (7 of 38 people)

Drug effectiveness by age:

Singulair:
  • 0-1: 0.0% - (0 of 1 people)
  • 2-9: 42.0% - (3 of 7 people)
  • 10-19: 25.0% - (2 of 8 people)
  • 20-29: 66.0% - (6 of 9 people)
  • 30-39: 33.0% - (5 of 15 people)
  • 40-49: 60.0% - (17 of 28 people)
  • 50-59: 42.0% - (11 of 26 people)
  • 60+: 27.0% - (6 of 22 people)
Loratadine:
  • 0-1: 0.0% - (0 of 1 people)
  • 2-9: 0.0% - (0 of 7 people)
  • 10-19: 28.0% - (2 of 7 people)
  • 20-29: 22.0% - (2 of 9 people)
  • 30-39: 20.0% - (3 of 15 people)
  • 40-49: 50.0% - (14 of 28 people)
  • 50-59: 37.0% - (10 of 27 people)
  • 60+: 18.0% - (4 of 22 people)

Most common drug interactions over time *:

< 1 month:
  • headache
  • obsessive thoughts
  • abnormal dreams
  • convulsion
  • depression
  • fear
  • appendix disorder
  • completed suicide
  • oropharyngeal pain
  • aggression
1 - 6 months:
  • suicidal ideation
  • hepatic function abnormal
  • mood altered
  • pulmonary eosinophilia
  • cardiac failure congestive
  • constipation
  • depression
  • headache
  • heart rate increased
  • ventricular extrasystoles
6 - 12 months:
  • suicidal ideation
  • hallucination, auditory
  • dizziness
  • fatigue
  • hepatic function abnormal
  • nausea
  • petit mal epilepsy
  • abdominal pain
  • aggression
  • anaemia
1 - 2 years:
  • leukocytoclastic vasculitis
  • tubulointerstitial nephritis
  • allergic granulomatous angiitis
  • anorexia
  • malaise
  • hyperglobulinaemia
  • asthma
  • lymphocyte stimulation test positive
  • nephritis interstitial
  • vasculitis
2 - 5 years:
  • headache
  • syncope
  • suicidal ideation
  • depression
  • dizziness
  • nausea
  • diarrhea
  • dehydration
  • vertigo
  • diarrhoea
5 - 10 years:
  • anxiety
  • pulmonary embolism
  • depression
  • bipolar disorder
  • cardiac disorder
  • cholelithiasis
  • emotional distress
  • mood swings
  • pain
  • psychological trauma
10+ years:
  • anxiety
  • pulmonary embolism
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • pain
  • acute myeloid leukemia (aml)
  • bronchitis acute
  • cholecystitis chronic
  • constipation
  • dementia
  • dizziness
not specified:
  • nausea
  • asthma
  • dyspnoea
  • pain
  • headache
  • fatigue
  • anxiety
  • drug ineffective
  • cough
  • depression

Most common drug interactions by gender *:

female:
  • nausea
  • dyspnoea
  • asthma
  • pain
  • headache
  • anxiety
  • cough
  • fatigue
  • depression
  • dizziness
male:
  • asthma
  • depression
  • dyspnoea
  • pain
  • drug ineffective
  • nausea
  • headache
  • fatigue
  • dizziness
  • chest pain

Most common drug interactions by age *:

0-1:
  • asthma aggravated
  • drug exposure during pregnancy
  • alopecia
  • atelectasis
  • blood pressure increased
  • cardiac murmur
  • chest pain
  • cleft lip and palate
  • complications of maternal exposure to therapeutic drugs
  • congenital cystic lung
2-9:
  • aggression
  • suicidal ideation
  • depression
  • crying
  • vomiting
  • abnormal behaviour
  • pyrexia
  • fear
  • drug ineffective
  • headache
10-19:
  • suicidal ideation
  • asthma
  • headache
  • cholecystitis chronic
  • nausea
  • abdominal pain upper
  • syncope
  • depression
  • cholelithiasis
  • dyspnoea
20-29:
  • cholecystitis chronic
  • pain
  • nausea
  • asthma
  • cholelithiasis
  • gallbladder disorder
  • abdominal pain
  • anxiety
  • convulsion
  • respiratory failure
30-39:
  • anxiety
  • pulmonary embolism
  • pain
  • asthma
  • depression
  • nausea
  • insomnia
  • weight increased
  • emotional distress
  • deep vein thrombosis
40-49:
  • pancreatitis
  • dyspnoea
  • pain
  • headache
  • anxiety
  • asthma
  • dizziness
  • cough
  • chest pain
  • fatigue
50-59:
  • nausea
  • depression
  • asthma
  • headache
  • fall
  • pyrexia
  • fatigue
  • insomnia
  • anxiety
  • diarrhoea
60+:
  • dyspnoea
  • nausea
  • pain
  • chronic obstructive pulmonary disease
  • cough
  • asthma
  • dehydration
  • pneumonia
  • cardiac failure congestive
  • drug ineffective

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Singulair (montelukast sodium) is often used to treat asthma. Loratadine (loratadine) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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