Review: taking Spiriva and Chantix together


Summary

Drug interactions are reported among people who take Spiriva and Chantix together. This review analyzes the effectiveness and drug interactions between Spiriva and Chantix. It is created by eHealthMe based on reports of 1,750 people who take the same drugs from FDA and social media, and is updated regularly.

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Spiriva

Spiriva has active ingredients of tiotropium bromide monohydrate. It is often used in chronic obstructive pulmonary disease. (latest outcomes from Spiriva 88,363 users)

Chantix

Chantix has active ingredients of varenicline tartrate. It is often used in quit smoking. (latest outcomes from Chantix 74,863 users)

On Sep, 15, 2016

1,750 people who take Spiriva, Chantix are studied.


Number of reports submitted per year:

Spiriva and Chantix drug interactions.

Drug effectiveness over time:

Spiriva:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 50.0% - (2 of 4 people)
  • 6 - 12 months: 50.0% - (1 of 2 people)
  • 1 - 2 years: 33.0% - (1 of 3 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Chantix:
  • < 1 month: 66.0% - (2 of 3 people)
  • 1 - 6 months: 80.0% - (4 of 5 people)
  • 6 - 12 months: 100.0% - (2 of 2 people)
  • 1 - 2 years: 50.0% - (1 of 2 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Spiriva:
  • female: 62.0% - (5 of 8 people)
  • male: 20.0% - (1 of 5 people)
Chantix:
  • female: 87.0% - (7 of 8 people)
  • male: 50.0% - (2 of 4 people)

Drug effectiveness by age:

Spiriva:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 100.0% - (1 of 1 people)
  • 50-59: 57.0% - (4 of 7 people)
  • 60+: 25.0% - (1 of 4 people)
Chantix:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 100.0% - (1 of 1 people)
  • 50-59: 66.0% - (4 of 6 people)
  • 60+: 100.0% - (4 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • nausea
  • dyspnoea
  • vomiting
  • abnormal dreams
  • malaise
  • feeling abnormal
  • drug ineffective
  • chronic obstructive pulmonary disease
  • dizziness
  • insomnia
1 - 6 months:
  • depression
  • anxiety
  • nausea
  • suicidal ideation
  • insomnia
  • drug ineffective
  • dyspnoea
  • weight increased
  • abnormal behaviour
  • aggression
6 - 12 months:
  • abnormal dreams
  • depression
  • anxiety
  • nausea
  • aggression
  • chronic obstructive pulmonary disease
  • dyspnoea
  • dysgeusia
  • weight increased
  • abnormal behaviour
1 - 2 years:
  • depression
  • anxiety
  • drug ineffective
  • fatigue
  • oedema peripheral
  • feeling abnormal
  • abnormal dreams
  • dyspnoea
  • insomnia
  • nightmare
2 - 5 years:
  • anxiety
  • depression
  • aggression
  • suicide attempt
  • bipolar disorder
  • intentional overdose
  • suicidal ideation
  • fall
  • insomnia
  • abnormal behaviour
5 - 10 years:
  • abnormal dreams
  • adjustment disorder
  • agitation
  • amnesia
  • cardiac disorder
  • disturbance in attention
  • emotional disorder
  • hypotension
  • insomnia
  • loss of consciousness
not specified:
  • nausea
  • dyspnoea
  • anxiety
  • vomiting
  • chronic obstructive pulmonary disease
  • abnormal dreams
  • pain
  • depression
  • insomnia
  • drug ineffective

Most common drug interactions by gender *:

female:
  • nausea
  • dyspnoea
  • vomiting
  • abnormal dreams
  • anxiety
  • malaise
  • depression
  • weight increased
  • drug ineffective
  • chronic obstructive pulmonary disease
male:
  • dyspnoea
  • anxiety
  • chronic obstructive pulmonary disease
  • nausea
  • depression
  • insomnia
  • pain
  • bronchitis
  • back pain
  • drug ineffective

Most common drug interactions by age *:

2-9:
  • abasia
  • arthralgia
  • bursitis
  • femur fracture
  • pain in extremity
  • stress fracture
  • cardiac disorder
20-29:
  • pharyngeal oedema
  • dysphagia
  • swollen tongue
30-39:
  • anxiety
  • weight increased
  • suicidal ideation
  • diarrhoea
  • malaise
  • neuropathy peripheral
  • fatigue
  • infection
  • neutropenia
  • back pain
40-49:
  • nausea
  • anxiety
  • vomiting
  • dyspnoea
  • depression
  • chest pain
  • chronic obstructive pulmonary disease
  • oedema peripheral
  • suicidal ideation
  • diarrhoea
50-59:
  • nausea
  • drug ineffective
  • abnormal dreams
  • dyspnoea
  • vomiting
  • stress
  • nervousness
  • anxiety
  • malaise
  • dizziness
60+:
  • nausea
  • dyspnoea
  • anxiety
  • chronic obstructive pulmonary disease
  • abnormal dreams
  • insomnia
  • vomiting
  • depression
  • pain
  • tremor

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Spiriva (tiotropium bromide monohydrate) is often used to treat chronic obstructive pulmonary disease. Chantix (varenicline tartrate) is often used to treat quit smoking. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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