Spironolactone and Benadryl drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Spironolactone and Benadryl together. This review analyzes the effectiveness and drug interactions between Spironolactone and Benadryl. It is created by eHealthMe based on reports of 1,111 people who take the same drugs from FDA, and is updated regularly.

What to expect?

If you take Spironolactone and Benadryl, find out what symptoms you could have in 1 year or longer.

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Spironolactone

Spironolactone has active ingredients of spironolactone. It is often used in acne. (latest outcomes from Spironolactone 43,283 users)

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (latest outcomes from Benadryl 44,713 users)

On Feb, 04, 2017

1,111 people who take Spironolactone, Benadryl are studied.


Number of reports submitted per year:

Spironolactone and Benadryl drug interactions.

Most common drug interactions over time *:

< 1 month:
  • dyspnoea
  • diarrhoea
  • asthenia
  • dizziness
  • orthostatic hypotension
  • anaemia
  • chest discomfort
  • lethargy
  • nausea
  • neutrophil count decreased
1 - 6 months:
  • stevens-johnson syndrome
  • nausea
  • vomiting
  • arthralgia
  • oedema peripheral
  • anxiety
  • death
  • diarrhoea
  • drug ineffective
  • malaise
6 - 12 months:
  • abdominal pain
  • accidental overdose
  • agitation
  • anxiety
  • azotaemia
  • cellulitis
  • cholecystitis
  • chronic obstructive pulmonary disease
  • confusional state
  • deep vein thrombosis
1 - 2 years:
  • listeria sepsis
  • pseudomonal bacteraemia
2 - 5 years:
  • oropharyngeal pain
  • tendon disorder
  • weight increased
  • arthralgia
  • arthropathy
  • bone pain
  • bursitis
  • cough
  • death
  • malaise
10+ years:
  • constipation
  • depression
  • road traffic accident
not specified:
  • dyspnoea
  • nausea
  • fatigue
  • pain
  • pneumonia
  • vomiting
  • diarrhoea
  • cardiac failure congestive
  • anxiety
  • headache

Most common drug interactions by gender *:

female:
  • nausea
  • dyspnoea
  • pain
  • fatigue
  • anxiety
  • diarrhoea
  • vomiting
  • asthenia
  • headache
  • dizziness
male:
  • dyspnoea
  • nausea
  • cardiac failure congestive
  • fatigue
  • pneumonia
  • oedema peripheral
  • pain
  • back pain
  • hypotension
  • pulmonary hypertension

Most common drug interactions by age *:

0-1:
  • tachycardia
  • pyrexia
  • wheezing
  • respiratory distress
  • cardio-respiratory arrest
  • infection
  • vomiting
  • general physical health deterioration
  • hepatic failure
  • increased bronchial secretion
2-9:
  • tracheobronchitis
  • gastroenteritis viral
  • diarrhoea
  • fall
  • pseudomonal bacteraemia
  • tracheitis
  • retching
  • central line infection
  • staphylococcal infection
  • upper limb fracture
10-19:
  • nausea
  • vomiting
  • dyspnoea exertional
  • fatigue
  • abdominal pain
  • alanine aminotransferase increased
  • ascites
  • aspartate aminotransferase increased
  • blood alkaline phosphatase increased
  • blood bilirubin increased
20-29:
  • cardiac failure congestive
  • bronchitis
  • atrial fibrillation
  • dyspnoea
  • insomnia
  • sinusitis
  • abdominal pain upper
  • atelectasis
  • back pain
  • cardiomegaly
30-39:
  • cholelithiasis
  • nausea
  • chest pain
  • headache
  • abdominal pain upper
  • diarrhoea
  • injury
  • seizure
  • hereditary angioedema
  • deep vein thrombosis
40-49:
  • pain
  • dyspnoea
  • anxiety
  • oedema peripheral
  • headache
  • back pain
  • diarrhoea
  • hypotension
  • malaise
  • arthralgia
50-59:
  • dyspnoea
  • pain
  • cardiac failure congestive
  • headache
  • cough
  • nausea
  • fatigue
  • pneumonia
  • cholelithiasis
  • hepatic failure
60+:
  • nausea
  • asthenia
  • dyspnoea
  • fatigue
  • hypotension
  • diarrhoea
  • vomiting
  • anaemia
  • dizziness
  • pain

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Spironolactone and Benadryl?

Interactions between Spironolactone and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Benadryl and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Spironolactone (spironolactone) is often used to treat high blood pressure. Benadryl (diphenhydramine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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