Spironolactone and Omeprazole drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Spironolactone and Omeprazole together. This review analyzes the effectiveness and drug interactions between Spironolactone and Omeprazole. It is created by eHealthMe based on reports of 7,699 people who take the same drugs from FDA, and is updated regularly.

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If you take Spironolactone and Omeprazole, find out what symptoms you could have in 1 year or longer.

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Spironolactone

Spironolactone has active ingredients of spironolactone. It is often used in acne. (latest outcomes from Spironolactone 43,283 users)

Omeprazole

Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. (latest outcomes from Omeprazole 161,243 users)

On Jan, 23, 2017

7,699 people who take Spironolactone, Omeprazole are studied.


Number of reports submitted per year:

Spironolactone and Omeprazole drug interactions.

Most common drug interactions over time *:

< 1 month:
  • drug rash with eosinophilia and systemic symptoms
  • hyperkalaemia
  • pneumonia
  • malaise
  • hepatic encephalopathy
  • dyspnoea
  • decreased appetite
  • pyrexia
  • nausea
  • cardiac failure
1 - 6 months:
  • renal failure acute
  • hyperkalaemia
  • dyspnoea
  • nausea
  • ascites
  • stevens-johnson syndrome
  • constipation
  • pancytopenia
  • vomiting
  • cough
6 - 12 months:
  • renal failure acute
  • fatigue
  • ascites
  • hyperkalaemia
  • myalgia
  • malaise
  • tubulointerstitial nephritis
  • asthenia
  • bone disorder
  • decreased appetite
1 - 2 years:
  • renal failure acute
  • hyperkalaemia
  • hyponatraemia
  • pulmonary embolism
  • fall
  • dyspnoea
  • acidosis
  • anxiety
  • arrhythmia
  • asthenia
2 - 5 years:
  • renal failure acute
  • hyperkalaemia
  • pulmonary embolism
  • pulmonary hypertension
  • hepatic encephalopathy
  • abdominal pain
  • dyspnoea
  • gastrointestinal haemorrhage
  • renal impairment
  • chest pain
5 - 10 years:
  • hypocalcaemia
  • hypokalaemia
  • hypomagnesaemia
  • agitation
  • hallucination
  • muscle disorder
  • hypophosphataemia
  • weight decreased
  • diarrhoea
  • vomiting
10+ years:
  • nephrotic syndrome
  • gastrointestinal haemorrhage
  • fall
  • haematuria
  • upper gastrointestinal haemorrhage
  • hyperkalaemia
  • renal failure
  • acute myocardial infarction
  • atrial fibrillation
  • blood calcium decreased
not specified:
  • dyspnoea
  • nausea
  • fatigue
  • fall
  • pain
  • vomiting
  • diarrhoea
  • oedema peripheral
  • anaemia
  • cardiac failure congestive

Most common drug interactions by gender *:

female:
  • nausea
  • dyspnoea
  • pain
  • fatigue
  • fall
  • diarrhoea
  • vomiting
  • oedema peripheral
  • renal failure acute
  • asthenia
male:
  • dyspnoea
  • nausea
  • fatigue
  • fall
  • cardiac failure congestive
  • hypotension
  • pain
  • vomiting
  • pneumonia
  • renal failure acute

Most common drug interactions by age *:

0-1:
  • blood creatine phosphokinase increased
  • haematuria
  • hypertonia
  • muscle rigidity
  • seizure
  • subdural haemorrhage
  • chronic obstructive pulmonary disease
  • pyrexia
  • acquired methaemoglobinaemia
  • drug withdrawal syndrome neonatal
2-9:
  • abdominal pain
  • cholecystitis acute
  • diarrhoea
  • crying
  • tracheitis
  • nightmare
  • screaming
  • cholelithiasis
  • dehydration
  • pancytopenia
10-19:
  • drug rash with eosinophilia and systemic symptoms
  • malaise
  • hypotension
  • pyrexia
  • ascites
  • abnormal behaviour
  • atelectasis
  • computerised tomogram abnormal
  • convulsion
  • decreased appetite
20-29:
  • anxiety
  • abdominal pain
  • anaemia
  • depression
  • gastrooesophageal reflux disease
  • weight decreased
  • haematochezia
  • dehydration
  • colitis
  • colitis ulcerative
30-39:
  • nausea
  • pain
  • anxiety
  • malaise
  • pyrexia
  • abdominal pain
  • vomiting
  • cholecystitis chronic
  • dyspnoea
  • depression
40-49:
  • nausea
  • pyrexia
  • back pain
  • dehydration
  • gastrooesophageal reflux disease
  • oedema
  • weight increased
  • fatigue
  • hypertension
  • vomiting
50-59:
  • dyspnoea
  • nausea
  • fall
  • fatigue
  • pain
  • vomiting
  • diarrhoea
  • cough
  • ascites
  • abdominal pain
60+:
  • dyspnoea
  • nausea
  • fall
  • renal failure acute
  • fatigue
  • diarrhoea
  • cardiac failure congestive
  • pain
  • vomiting
  • hypotension

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Spironolactone and Omeprazole?

Interactions between Spironolactone and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Omeprazole and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Spironolactone (spironolactone) is often used to treat high blood pressure. Omeprazole (omeprazole) is often used to treat gastrooesophageal reflux disease. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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