Review: taking Suboxone and Methadone hydrochloride together


Summary

Drug interactions are reported among people who take Suboxone and Methadone hydrochloride together. This review analyzes the effectiveness and drug interactions between Suboxone and Methadone hydrochloride. It is created by eHealthMe based on reports of 166 people who take the same drugs from FDA and social media, and is updated regularly.

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Suboxone

Suboxone has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is often used in drug dependence. (latest outcomes from Suboxone 10,832 users)

Methadone Hydrochloride

Methadone hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. (latest outcomes from Methadone hydrochloride 2,998 users)

On Aug, 25, 2016

166 people who take Suboxone, Methadone Hydrochloride are studied.


Number of reports submitted per year:

Suboxone and Methadone hydrochloride drug interactions.

Drug effectiveness over time:

Suboxone:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 66.0% - (2 of 3 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Methadone Hydrochloride:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Suboxone:
  • female: 50.0% - (1 of 2 people)
  • male: 50.0% - (1 of 2 people)
Methadone Hydrochloride:
  • female: 0.0% - (0 of 3 people)
  • male: 0.0% - (0 of 1 people)

Drug effectiveness by age:

Suboxone:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 50.0% - (1 of 2 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 0 people)
Methadone Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 2 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • drug withdrawal syndrome
  • drug exposure during pregnancy
  • foetal exposure during pregnancy
  • insomnia
  • nausea
  • nephrolithiasis
  • pain
  • substance abuse
  • agitation
  • electrocardiogram qt prolonged
1 - 6 months:
  • foetal exposure during pregnancy
  • drug exposure during pregnancy
  • drug withdrawal syndrome neonatal
  • drug withdrawal syndrome
  • abortion spontaneous
  • completed suicide
  • drug abuse
  • headache
  • intentional overdose
  • maternal exposure during pregnancy
6 - 12 months:
  • foetal exposure during pregnancy
  • foetal heart rate decreased
  • premature baby
  • premature delivery
  • premature labour
  • abdominal distension
  • abnormal loss of weight
  • abortion spontaneous
  • arthralgia
  • cryptorchism
1 - 2 years:
  • intentional overdose
  • completed suicide
  • drug abuse
  • substance abuse
  • cerebral ischaemia
  • depression
  • drug dependence
  • drug exposure during pregnancy
  • drug withdrawal syndrome
  • fatigue
2 - 5 years:
  • drug withdrawal syndrome
  • insomnia
  • agitation
  • appetite disorder
  • convulsion
  • hallucination
  • headache
  • pneumonia
  • sensation of heaviness
  • somnolence
5 - 10 years:
  • blood pressure increased
  • cardiac arrest
  • cardiac failure congestive
  • cardiac valve disease
  • chest pain
  • coma
  • fatigue
  • heart rate irregular
  • migraine
  • rib fracture
not specified:
  • drug withdrawal syndrome
  • drug abuse
  • overdose
  • vomiting
  • substance abuse
  • insomnia
  • drug dependence
  • malaise
  • convulsion
  • death

Most common drug interactions by gender *:

female:
  • drug withdrawal syndrome
  • substance abuse
  • drug exposure during pregnancy
  • drug abuse
  • foetal exposure during pregnancy
  • premature delivery
  • vomiting
  • premature labour
  • insomnia
  • maternal exposure during pregnancy
male:
  • drug withdrawal syndrome
  • drug abuse
  • insomnia
  • overdose
  • convulsion
  • vomiting
  • tremor
  • drug dependence
  • malaise
  • accidental overdose

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • cryptorchism
  • drug exposure during pregnancy
  • drug withdrawal syndrome neonatal
  • sudden infant death syndrome
  • talipes
10-19:
  • accidental overdose
  • brain oedema
  • drug toxicity
  • headache
  • papilloedema
  • drug abuse
  • drug screen positive
  • vision blurred
20-29:
  • drug abuse
  • respiratory arrest
  • cardiac arrest
  • maternal exposure during pregnancy
  • substance abuse
  • abdominal pain
  • cholelithiasis
  • decreased appetite
  • gallbladder disorder
  • gallbladder pain
30-39:
  • drug exposure during pregnancy
  • drug withdrawal syndrome
  • vomiting
  • fatigue
  • premature labour
  • substance abuse
  • blood pressure increased
  • cardiac arrest
  • cardiac failure congestive
  • cardiac valve disease
40-49:
  • drug withdrawal syndrome
  • substance abuse
  • insomnia
  • somnolence
  • drug dependence
  • suicidal ideation
  • overdose
  • anxiety
  • apathy
  • appetite disorder
50-59:
  • drug withdrawal syndrome
  • dehydration
  • drug abuse
  • agitation
  • diarrhoea
  • insomnia
  • malaise
  • pain
  • tremor
  • constipation
60+:
  • drug withdrawal syndrome
  • hypertension
  • drug abuse
  • electrocardiogram qt prolonged
  • foetal heart rate decreased
  • premature delivery
  • premature labour
  • vomiting
  • drug dependence
  • nervous system disorder

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Suboxone (buprenorphine hydrochloride; naloxone hydrochloride) is often used to treat drug dependence. Methadone hydrochloride (methadone hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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