Review: taking Suboxone and Methadone hydrochloride together


Summary

Drug interactions are reported among people who take Suboxone and Methadone hydrochloride together. This review analyzes the effectiveness and drug interactions between Suboxone and Methadone hydrochloride. It is created by eHealthMe based on reports of 112 people who take the same drugs from FDA and social media, and is updated regularly.

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Suboxone

Suboxone has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is often used in drug dependence. (latest outcomes from Suboxone 8,195 users)

Methadone Hydrochloride

Methadone hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. (latest outcomes from Methadone hydrochloride 2,744 users)

On Jul, 24, 2016

112 people who take Suboxone, Methadone Hydrochloride are studied.


Number of reports submitted per year:

Suboxone and Methadone hydrochloride drug interactions.

Drug effectiveness over time:

Suboxone:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 66.0% - (2 of 3 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Methadone Hydrochloride:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Suboxone:
  • female: 50.0% - (1 of 2 people)
  • male: 50.0% - (1 of 2 people)
Methadone Hydrochloride:
  • female: 0.0% - (0 of 3 people)
  • male: 0.0% - (0 of 1 people)

Drug effectiveness by age:

Suboxone:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 50.0% - (1 of 2 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 0 people)
Methadone Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 2 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • drug exposure during pregnancy
  • insomnia
  • nausea
  • drug withdrawal syndrome
  • nephrolithiasis
  • pain
  • electrocardiogram qt prolonged
  • haematochezia
  • malaise
  • agitation
1 - 6 months:
  • drug exposure during pregnancy
  • drug withdrawal syndrome neonatal
  • completed suicide
  • drug withdrawal syndrome
  • headache
  • intentional overdose
  • pneumonia
  • abdominal pain
  • abortion spontaneous
  • appetite disorder
6 - 12 months:
  • abortion spontaneous
  • drug dependence
  • drug exposure during pregnancy
  • maternal exposure during pregnancy
  • premature baby
1 - 2 years:
  • intentional overdose
  • completed suicide
  • cerebral ischaemia
  • depression
  • drug abuse
  • drug dependence
  • drug exposure during pregnancy
  • fatigue
  • hallucination
  • maternal exposure during pregnancy
2 - 5 years:
  • appetite disorder
  • convulsion
  • drug withdrawal syndrome
  • headache
  • insomnia
  • pneumonia
  • accidental overdose
  • amnesia
  • drug toxicity
  • elevated mood
5 - 10 years:
  • blood pressure increased
  • cardiac arrest
  • cardiac failure congestive
  • cardiac valve disease
  • chest pain
  • coma
  • fatigue
  • heart rate irregular
  • migraine
  • rib fracture
not specified:
  • drug withdrawal syndrome
  • overdose
  • drug abuse
  • vomiting
  • insomnia
  • malaise
  • dehydration
  • pain
  • blood pressure increased
  • cardiac arrest

Most common drug interactions by gender *:

female:
  • drug exposure during pregnancy
  • drug withdrawal syndrome
  • substance abuse
  • blood pressure increased
  • insomnia
  • maternal exposure during pregnancy
  • nausea
  • vomiting
  • fatigue
  • pneumonia
male:
  • drug withdrawal syndrome
  • convulsion
  • insomnia
  • overdose
  • drug abuse
  • malaise
  • amnesia
  • intentional overdose
  • pain
  • tremor

Most common drug interactions by age *:

0-1:
  • drug exposure during pregnancy
  • drug withdrawal syndrome neonatal
10-19:
  • accidental overdose
  • brain oedema
  • drug toxicity
  • headache
  • papilloedema
  • drug screen positive
  • vision blurred
20-29:
  • drug abuse
  • cardiac arrest
  • respiratory arrest
  • abdominal pain
  • cholelithiasis
  • decreased appetite
  • gallbladder disorder
  • gallbladder pain
  • hypoglycaemia
  • maternal exposure during pregnancy
30-39:
  • drug exposure during pregnancy
  • vomiting
  • fatigue
  • drug withdrawal syndrome
  • premature labour
  • blood pressure increased
  • cardiac arrest
  • cardiac failure congestive
  • cardiac valve disease
  • chest pain
40-49:
  • insomnia
  • drug withdrawal syndrome
  • overdose
  • somnolence
  • anxiety
  • apathy
  • appetite disorder
  • confusional state
  • convulsion
  • cystitis
50-59:
  • dehydration
  • drug withdrawal syndrome
  • insomnia
  • malaise
  • pain
  • drug abuse
  • amnesia
  • bruxism
  • cold sweat
  • convulsion
60+:
  • drug withdrawal syndrome
  • electrocardiogram qt prolonged
  • blindness transient
  • blood pressure increased
  • glycosylated haemoglobin increased
  • stupor
  • surgery
  • depression
  • drug dependence
  • fatigue

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Suboxone (buprenorphine hydrochloride; naloxone hydrochloride) is often used to treat drug dependence. Methadone hydrochloride (methadone hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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