Review: taking Symbicort and Simvastatin together


Summary

Drug interactions are reported among people who take Symbicort and Simvastatin together. This review analyzes the effectiveness and drug interactions between Symbicort and Simvastatin. It is created by eHealthMe based on reports of 1,340 people who take the same drugs from FDA and social media, and is updated regularly.

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Symbicort

Symbicort has active ingredients of budesonide; formoterol fumarate dihydrate. It is often used in asthma. (latest outcomes from Symbicort 24,831 users)

Simvastatin

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. (latest outcomes from Simvastatin 94,390 users)

On Aug, 21, 2016

1,340 people who take Symbicort, Simvastatin are studied.


Number of reports submitted per year:

Symbicort and Simvastatin drug interactions.

Drug effectiveness over time:

Symbicort:
  • < 1 month: 50.0% - (1 of 2 people)
  • 1 - 6 months: 60.0% - (3 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 66.0% - (2 of 3 people)
  • 2 - 5 years: 100.0% - (2 of 2 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 50.0% - (1 of 2 people)
  • not specified: 0.0% - (0 of 0 people)
Simvastatin:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 50.0% - (1 of 2 people)
  • 6 - 12 months: 100.0% - (2 of 2 people)
  • 1 - 2 years: 60.0% - (3 of 5 people)
  • 2 - 5 years: 42.0% - (3 of 7 people)
  • 5 - 10 years: 33.0% - (1 of 3 people)
  • 10+ years: 50.0% - (1 of 2 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Symbicort:
  • female: 66.0% - (6 of 9 people)
  • male: 50.0% - (4 of 8 people)
Simvastatin:
  • female: 44.0% - (4 of 9 people)
  • male: 53.0% - (7 of 13 people)

Drug effectiveness by age:

Symbicort:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 100.0% - (3 of 3 people)
  • 50-59: 57.0% - (4 of 7 people)
  • 60+: 42.0% - (3 of 7 people)
Simvastatin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 100.0% - (1 of 1 people)
  • 40-49: 50.0% - (2 of 4 people)
  • 50-59: 57.0% - (4 of 7 people)
  • 60+: 40.0% - (4 of 10 people)

Most common drug interactions over time *:

< 1 month:
  • oedema mouth
  • eye swelling
  • rash macular
  • cataract
  • dyspnoea
  • dizziness
  • headache
  • diarrhoea
  • pruritus
  • myalgia
1 - 6 months:
  • asthma
  • diarrhoea
  • exercise tolerance decreased
  • headache
  • dyspnoea
  • chronic obstructive pulmonary disease
  • cough
  • neutropenia
  • oropharyngeal pain
  • pharyngeal disorder
6 - 12 months:
  • asthma
  • drug ineffective
  • ecchymosis
  • fibromyalgia
  • frequent headaches
  • haemoglobin decreased
  • platelet count decreased
  • wheezing
1 - 2 years:
  • gastroenteritis norovirus
  • hypotension
  • renal failure acute
  • tachycardia
  • dizziness
  • myocardial infarction
  • rash
  • arthritis
  • asthenia
  • atrial fibrillation
2 - 5 years:
  • cough
  • asthma
  • dyspnoea
  • early morning joint stiffness
  • exomphalos
  • frequent bowel movements
  • hip arthroplasty
  • irritability
  • muscle fatigue
  • drug ineffective
5 - 10 years:
  • extensive interdialytic weight gain
  • muscle cramps aggravated
  • simvastatin
10+ years:
  • fibromuscular dysplasia
  • pancreatitis
  • pyrexia
  • simvastatin
  • speech disorder
  • withdrawal syndrome
not specified:
  • dyspnoea
  • pneumonia
  • chronic obstructive pulmonary disease
  • fatigue
  • cough
  • dizziness
  • chest pain
  • nausea
  • diarrhoea
  • pain

Most common drug interactions by gender *:

female:
  • dyspnoea
  • fatigue
  • chronic obstructive pulmonary disease
  • nausea
  • dizziness
  • cough
  • diarrhoea
  • anxiety
  • arthralgia
  • pain
male:
  • dyspnoea
  • pneumonia
  • chest pain
  • cough
  • dizziness
  • nausea
  • drug ineffective
  • blood glucose increased
  • headache
  • pruritus

Most common drug interactions by age *:

0-1:
  • chronic obstructive pulmonary disease
  • convulsion
  • cough
  • dysphagia
  • enlarged uvula
  • swollen tongue
  • tachycardia
10-19:
  • adverse event
  • blood cholesterol increased
  • body height decreased
  • cardiovascular disorder
  • chronic obstructive pulmonary disease
  • dyspepsia
  • dysphagia
  • dyspnoea
  • gait disturbance
  • gastrooesophageal reflux disease
20-29:
  • diarrhoea
  • local swelling
  • nausea
  • abdominal distension
  • cardiac disorder
  • cough
  • drug ineffective
  • emotional distress
  • gastroenteritis bacterial
  • neutrophil count increased
30-39:
  • abdominal pain lower
  • carcinoembryonic antigen increased
  • helicobacter gastritis
  • iron overload
  • lymphadenitis
  • lymphangioma
  • ovarian cyst
  • trigeminal neuralgia
  • deep vein thrombosis
  • hyperandrogenism
40-49:
  • dyspnoea
  • pain
  • deep vein thrombosis
  • anxiety
  • chest pain
  • diarrhoea
  • dizziness
  • emotional distress
  • chronic obstructive pulmonary disease
  • nausea
50-59:
  • dyspnoea
  • cough
  • nausea
  • vomiting
  • dizziness
  • pneumonia
  • chest pain
  • fatigue
  • malaise
  • asthma
60+:
  • dyspnoea
  • pneumonia
  • cough
  • dizziness
  • chronic obstructive pulmonary disease
  • chest pain
  • arthralgia
  • diarrhoea
  • drug ineffective
  • malaise

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Symbicort (budesonide; formoterol fumarate dihydrate) is often used to treat asthma. Simvastatin (simvastatin) is often used to treat high blood cholesterol. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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