Synthroid and Melatonin drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Synthroid and Melatonin together. This review analyzes the effectiveness and drug interactions between Synthroid and Melatonin. It is created by eHealthMe based on reports of 1,265 people who take the same drugs from FDA, and is updated regularly.

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Synthroid

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. (latest outcomes from Synthroid 137,580 users)

Melatonin

Melatonin has active ingredients of melatonin. It is often used in insomnia. (latest outcomes from Melatonin 9,321 users)

On Feb, 05, 2017

1,265 people who take Synthroid, Melatonin are studied.


Number of reports submitted per year:

Synthroid and Melatonin drug interactions.

Most common drug interactions over time *:

< 1 month:
  • antepartum haemorrhage
  • headache
  • arrhythmia
  • dehydration
  • fatigue
  • nasopharyngitis
  • plasma cell myeloma
  • pruritus
  • rash maculo-papular
  • subchorionic haemorrhage
1 - 6 months:
  • alopecia
  • anxiety
  • constipation
  • diarrhoea
  • dry eye
  • dry mouth
  • insomnia
  • arthralgia
  • blood thyroid stimulating hormone increased
  • dry skin
6 - 12 months:
  • alopecia
  • change of bowel habit
  • constipation
  • diarrhoea
  • flatulence
  • irritable bowel syndrome
  • blood thyroid stimulating hormone increased
  • drug ineffective
  • metrorrhagia
  • weight decreased
1 - 2 years:
  • dry mouth
  • fall
  • insomnia
  • alopecia
  • anxiety
  • apnoea
  • arthralgia
  • balance disorder
  • blood thyroid stimulating hormone increased
  • constipation
2 - 5 years:
  • abdominal discomfort
  • cholecystitis
  • gallbladder cholesterolosis
  • gallbladder disorder
  • influenza like illness
  • organ failure
5 - 10 years:
  • alopecia
  • anxiety
  • feeling abnormal
  • gastrooesophageal reflux disease
  • insomnia
  • mood swings
10+ years:
  • insomnia
  • alopecia
  • anxiety
  • arthropathy
  • drug ineffective
  • exercise tolerance decreased
  • fatigue
  • feeling abnormal
  • gastrooesophageal reflux disease
  • mood swings
not specified:
  • fatigue
  • nausea
  • headache
  • diarrhoea
  • drug ineffective
  • pain
  • fall
  • insomnia
  • dyspnoea
  • malaise

Most common drug interactions by gender *:

female:
  • fatigue
  • nausea
  • headache
  • diarrhoea
  • drug ineffective
  • pain
  • insomnia
  • fall
  • dyspnoea
  • dizziness
male:
  • fatigue
  • fall
  • drug ineffective
  • chest pain
  • pain
  • malaise
  • asthenia
  • dyspnoea
  • gastrooesophageal reflux disease
  • pneumonia

Most common drug interactions by age *:

0-1:
  • blood thyroid stimulating hormone decreased
  • hypopnoea
  • pneumonia
  • respiratory depression
  • respiratory distress
2-9:
  • abdominal pain
  • arterial occlusive disease
  • cerebrovascular accident
  • dehydration
  • diarrhoea
  • pneumonia
  • pulmonary oedema
  • radiation injury
  • skin hypertrophy
  • vasculitis
10-19:
  • pain
  • chest pain
  • drug ineffective
  • dyspepsia
  • gastrooesophageal reflux disease
  • malaise
  • panic attack
  • thyroid disorder
  • fall
  • fatigue
20-29:
  • hyponatraemia
  • seizure
  • gastrooesophageal reflux disease
  • hypothyroidism
  • depression
  • diarrhoea
  • hypotension
  • malaise
  • pyrexia
  • back pain
30-39:
  • headache
  • pain
  • convulsion
  • insomnia
  • abdominal pain upper
  • dizziness
  • dyspnoea
  • nausea
  • ovarian hyperstimulation syndrome
  • somnolence
40-49:
  • fatigue
  • decreased appetite
  • asthenia
  • completed suicide
  • diarrhoea
  • pyrexia
  • hypothyroidism
  • nausea
  • neuropathy peripheral
  • drug ineffective
50-59:
  • gastrooesophageal reflux disease
  • diarrhoea
  • drug ineffective
  • fatigue
  • insomnia
  • chest pain
  • headache
  • nausea
  • hand fracture
  • dyspepsia
60+:
  • nausea
  • fatigue
  • diarrhoea
  • dyspnoea
  • fall
  • headache
  • pain
  • drug ineffective
  • asthenia
  • dizziness

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Synthroid and Melatonin?

Interactions between Synthroid and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Melatonin and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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