Review: taking Tizanidine hydrochloride and Gabapentin together


Summary

Drug interactions are reported among people who take Tizanidine hydrochloride and Gabapentin together. This review analyzes the effectiveness and drug interactions between Tizanidine hydrochloride and Gabapentin. It is created by eHealthMe based on reports of 4,479 people who take the same drugs from FDA and social media, and is updated regularly.

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Tizanidine Hydrochloride

Tizanidine hydrochloride has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. (latest outcomes from Tizanidine hydrochloride 1,917 users)

Gabapentin

Gabapentin has active ingredients of gabapentin. It is often used in pain. (latest outcomes from Gabapentin 83,499 users)

On Sep, 17, 2016

4,479 people who take Tizanidine Hydrochloride, Gabapentin are studied.


Number of reports submitted per year:

Tizanidine hydrochloride and Gabapentin drug interactions.

Drug effectiveness over time:

Tizanidine Hydrochloride:
  • < 1 month: 25.0% - (3 of 12 people)
  • 1 - 6 months: 17.0% - (4 of 23 people)
  • 6 - 12 months: 21.0% - (5 of 23 people)
  • 1 - 2 years: 38.0% - (10 of 26 people)
  • 2 - 5 years: 42.0% - (9 of 21 people)
  • 5 - 10 years: 40.0% - (4 of 10 people)
  • 10+ years: 75.0% - (3 of 4 people)
  • not specified: 0.0% - (0 of 0 people)
Gabapentin:
  • < 1 month: 18.0% - (2 of 11 people)
  • 1 - 6 months: 23.0% - (6 of 26 people)
  • 6 - 12 months: 8.0% - (1 of 12 people)
  • 1 - 2 years: 22.0% - (5 of 22 people)
  • 2 - 5 years: 33.0% - (10 of 30 people)
  • 5 - 10 years: 23.0% - (3 of 13 people)
  • 10+ years: 60.0% - (3 of 5 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Tizanidine Hydrochloride:
  • female: 31.0% - (31 of 98 people)
  • male: 33.0% - (7 of 21 people)
Gabapentin:
  • female: 26.0% - (26 of 98 people)
  • male: 19.0% - (4 of 21 people)

Drug effectiveness by age:

Tizanidine Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 44.0% - (4 of 9 people)
  • 30-39: 26.0% - (7 of 26 people)
  • 40-49: 30.0% - (11 of 36 people)
  • 50-59: 41.0% - (16 of 39 people)
  • 60+: 0.0% - (0 of 9 people)
Gabapentin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 30.0% - (3 of 10 people)
  • 30-39: 26.0% - (7 of 26 people)
  • 40-49: 13.0% - (5 of 36 people)
  • 50-59: 34.0% - (13 of 38 people)
  • 60+: 22.0% - (2 of 9 people)

Most common drug interactions over time *:

< 1 month:
  • fall
  • nausea
  • somnolence
  • confusional state
  • drug ineffective
  • headache
  • weight increased
  • dehydration
  • dizziness
  • dry mouth
1 - 6 months:
  • pain
  • depression
  • dysarthria
  • fall
  • anxiety
  • headache
  • hyperhidrosis
  • drug ineffective
  • nausea
  • pulmonary embolism
6 - 12 months:
  • anxiety
  • arthralgia
  • dehydration
  • drug withdrawal syndrome
  • cushingoid
  • duodenal ulcer
  • dyspnoea
  • emotional distress
  • fatigue
  • insomnia
1 - 2 years:
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • iron deficiency anemia
  • pain inflammation activated
  • weight loss
  • anxiety
  • vertigo
  • neck pain
  • rigors
  • acid reflux
  • allergy to animal
2 - 5 years:
  • pain
  • insomnia
  • suicide attempt
  • depression
  • pain inflammation activated
  • anxiety
  • drug ineffective
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • iron deficiency anemia
  • road traffic accident
5 - 10 years:
  • mottled skin
  • skin burning sensation
  • fall
  • depression
  • loss of consciousness
  • anxiety
  • concussion
  • fatigue
  • hypotension
  • neuralgia
10+ years:
  • accidental overdose
  • activities of daily living impaired
  • adverse reaction
  • ankylosing spondylitis
  • anorexia
  • bladder prolapse
  • blood pressure increased
  • hypersensitivity
  • muscle atrophy
  • oedema
not specified:
  • pain
  • fall
  • nausea
  • depression
  • drug ineffective
  • headache
  • anxiety
  • fatigue
  • asthenia
  • dyspnoea

Most common drug interactions by gender *:

female:
  • pain
  • fall
  • nausea
  • fatigue
  • headache
  • drug ineffective
  • asthenia
  • depression
  • anxiety
  • dizziness
male:
  • pain
  • anxiety
  • depression
  • back pain
  • drug ineffective
  • headache
  • dyspnoea
  • pain in extremity
  • hypoaesthesia
  • asthenia

Most common drug interactions by age *:

0-1:
  • hepatitis c virus test positive
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • blood alkaline phosphatase increased
  • blood lactate dehydrogenase increased
  • bradycardia
  • dehydration
  • diarrhoea
  • drug effect decreased
  • epilepsy
2-9:
  • gait disturbance
  • multiple sclerosis relapse
  • nephrolithiasis
  • pneumonia staphylococcal
  • wisdom teeth removal
  • disturbance in attention
  • disturbance in social behaviour
  • drug ineffective
10-19:
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • blood alkaline phosphatase increased
  • blood lactate dehydrogenase increased
  • liver function test abnormal
  • headache
  • lethargy
  • constipation
  • dystonia
  • ileus
20-29:
  • muscle spasms
  • anxiety
  • drug ineffective
  • nausea
  • completed suicide
  • depression
  • vomiting
  • headache
  • injection site erythema
  • memory impairment
30-39:
  • pain
  • headache
  • anxiety
  • arthralgia
  • nausea
  • depression
  • dyspnoea
  • fatigue
  • asthenia
  • dizziness
40-49:
  • pain
  • depression
  • nausea
  • headache
  • fall
  • anxiety
  • drug ineffective
  • asthenia
  • muscle spasms
  • chest pain
50-59:
  • pain
  • fall
  • depression
  • fatigue
  • anxiety
  • back pain
  • headache
  • dyspnoea
  • nausea
  • asthenia
60+:
  • pain
  • fall
  • anxiety
  • drug ineffective
  • dyspnoea
  • fatigue
  • nausea
  • asthenia
  • dizziness
  • malaise

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Tizanidine hydrochloride (tizanidine hydrochloride) is often used to treat muscle spasms. Gabapentin (gabapentin) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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