Review: taking Tizanidine hydrochloride and Xanax together


Summary

Drug interactions are reported among people who take Tizanidine hydrochloride and Xanax together. This review analyzes the effectiveness and drug interactions between Tizanidine hydrochloride and Xanax. It is created by eHealthMe based on reports of 1,258 people who take the same drugs from FDA and social media, and is updated regularly.

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Tizanidine Hydrochloride

Tizanidine hydrochloride has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. (latest outcomes from Tizanidine hydrochloride 1,352 users)

Xanax

Xanax has active ingredients of alprazolam. It is often used in stress and anxiety. (latest outcomes from Xanax 58,007 users)

On Jul, 27, 2016

1,258 people who take Tizanidine Hydrochloride, Xanax are studied.


Number of reports submitted per year:

Tizanidine hydrochloride and Xanax drug interactions.

Drug effectiveness over time:

Tizanidine Hydrochloride:
  • < 1 month: 50.0% - (2 of 4 people)
  • 1 - 6 months: 71.0% - (23 of 32 people)
  • 6 - 12 months: 23.0% - (4 of 17 people)
  • 1 - 2 years: 29.0% - (5 of 17 people)
  • 2 - 5 years: 61.0% - (11 of 18 people)
  • 5 - 10 years: 75.0% - (3 of 4 people)
  • 10+ years: 50.0% - (2 of 4 people)
  • not specified: 0.0% - (0 of 0 people)
Xanax:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 92.0% - (23 of 25 people)
  • 6 - 12 months: 75.0% - (6 of 8 people)
  • 1 - 2 years: 40.0% - (6 of 15 people)
  • 2 - 5 years: 51.0% - (15 of 29 people)
  • 5 - 10 years: 87.0% - (7 of 8 people)
  • 10+ years: 84.0% - (11 of 13 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Tizanidine Hydrochloride:
  • female: 46.0% - (36 of 78 people)
  • male: 77.0% - (14 of 18 people)
Xanax:
  • female: 67.0% - (55 of 81 people)
  • male: 68.0% - (13 of 19 people)

Drug effectiveness by age:

Tizanidine Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 40.0% - (4 of 10 people)
  • 30-39: 9.0% - (1 of 11 people)
  • 40-49: 37.0% - (11 of 29 people)
  • 50-59: 71.0% - (23 of 32 people)
  • 60+: 78.0% - (11 of 14 people)
Xanax:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 72.0% - (8 of 11 people)
  • 30-39: 35.0% - (5 of 14 people)
  • 40-49: 72.0% - (21 of 29 people)
  • 50-59: 75.0% - (24 of 32 people)
  • 60+: 71.0% - (10 of 14 people)

Most common drug interactions over time *:

< 1 month:
  • hypotension
  • suicide attempt
  • depression
  • aggression
  • bipolar i disorder
  • burns third degree
  • dysphagia
  • emotional distress
  • hypoxia
  • injury
1 - 6 months:
  • pain - back
  • pain - joints
  • drug tolerance increased
  • duodenal ulcer perforation
  • itching
  • acute brain syndrome, acute confusional state, delirium
  • acute myocardial infarction
  • cardiac disorder
  • cardiogenic shock
  • cataract
6 - 12 months:
  • drug withdrawal syndrome
  • emotional distress
  • tremor
  • anxiety
  • arthralgia
  • cushingoid
  • dehydration
  • duodenal ulcer
  • dyspnoea
  • insomnia
1 - 2 years:
  • sudden memory loss
  • dizziness
  • hallucinations
  • personality change
  • change of bowel habit
  • diarrhea
  • anxiety
  • constipation
  • depression
  • abnormal dreams
2 - 5 years:
  • blood pressure increased
  • fatigue
  • headache
  • bleeding time prolonged
  • blood pressure diastolic increased
  • cognitive disorder
  • itching
  • migraine
  • neurotransmitter level altered
  • pain - head
5 - 10 years:
  • fatigue - chronic
  • fibromyalgia
  • night sweats
  • bleeding time prolonged
  • allergic dermatitis
  • seroma
10+ years:
  • hot flushes
  • pain - muscles
  • abscess - skin
  • back pain
  • body temperature fluctuation
  • breath odor
  • breathing difficulty
  • chest tightness or pressure
  • chills
  • cough
not specified:
  • fatigue
  • anxiety
  • nausea
  • pain
  • depression
  • fall
  • headache
  • dyspnoea
  • chest pain
  • dizziness

Most common drug interactions by gender *:

female:
  • nausea
  • fatigue
  • dyspnoea
  • pain
  • headache
  • anxiety
  • vomiting
  • fall
  • depression
  • chest pain
male:
  • depression
  • anxiety
  • insomnia
  • pain
  • fatigue
  • back pain
  • hypoaesthesia
  • drug dependence
  • pain in extremity
  • fall

Most common drug interactions by age *:

0-1:
  • balance disorder
  • bradycardia
  • cholecystitis chronic
  • convulsion
  • diabetic complication
  • dyspnoea
  • hyponatraemia
  • hypotension
  • nervous system disorder
  • orthopnoea
10-19:
  • drug screen positive
  • headache
  • somnolence
20-29:
  • nausea
  • vomiting
  • drug ineffective
  • fatigue
  • drug dependence
  • insomnia
  • pain
  • drug withdrawal syndrome
  • pancreatitis
  • abdominal pain upper
30-39:
  • arthralgia
  • nausea
  • anxiety
  • pain
  • hypoaesthesia
  • dyspnoea
  • drug withdrawal syndrome
  • headache
  • pain in extremity
  • asthenia
40-49:
  • depression
  • anxiety
  • headache
  • dyspnoea
  • chest pain
  • hypoaesthesia
  • fatigue
  • fall
  • pain
  • constipation
50-59:
  • fall
  • fatigue
  • progressive multifocal leukoencephalopathy
  • multiple sclerosis relapse
  • chest pain
  • pneumonia
  • pyrexia
  • back pain
  • pain
  • drug ineffective
60+:
  • fatigue
  • fall
  • urinary tract infection
  • nausea
  • pain
  • dyspnoea
  • tremor
  • anxiety
  • dizziness
  • depression

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Tizanidine hydrochloride (tizanidine hydrochloride) is often used to treat muscle spasms. Xanax (alprazolam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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