Review: taking Topamax and Ibuprofen together


Summary

Drug interactions are reported among people who take Topamax and Ibuprofen together. This review analyzes the effectiveness and drug interactions between Topamax and Ibuprofen. It is created by eHealthMe based on reports of 1,063 people who take the same drugs from FDA and social media, and is updated regularly.

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Topamax

Topamax has active ingredients of topiramate. It is often used in migraine. (latest outcomes from Topamax 24,312 users)

Ibuprofen

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from Ibuprofen 60,809 users)

On Jul, 27, 2016

1,063 people who take Topamax, Ibuprofen are studied.


Number of reports submitted per year:

Topamax and Ibuprofen drug interactions.

Drug effectiveness over time:

Topamax:
  • < 1 month: 66.0% - (2 of 3 people)
  • 1 - 6 months: 47.0% - (8 of 17 people)
  • 6 - 12 months: 0.0% - (0 of 2 people)
  • 1 - 2 years: 12.0% - (1 of 8 people)
  • 2 - 5 years: 0.0% - (0 of 5 people)
  • 5 - 10 years: 100.0% - (9 of 9 people)
  • 10+ years: 40.0% - (2 of 5 people)
  • not specified: 25.0% - (1 of 4 people)
Ibuprofen:
  • < 1 month: 28.0% - (2 of 7 people)
  • 1 - 6 months: 40.0% - (2 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 7 people)
  • 1 - 2 years: 0.0% - (0 of 5 people)
  • 2 - 5 years: 0.0% - (0 of 2 people)
  • 5 - 10 years: 40.0% - (2 of 5 people)
  • 10+ years: 0.0% - (0 of 14 people)
  • not specified: 66.0% - (4 of 6 people)

Drug effectiveness by gender:

Topamax:
  • female: 44.0% - (23 of 52 people)
  • male: 0.0% - (0 of 1 people)
Ibuprofen:
  • female: 20.0% - (10 of 50 people)
  • male: 0.0% - (0 of 1 people)

Drug effectiveness by age:

Topamax:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 50.0% - (1 of 2 people)
  • 20-29: 54.0% - (6 of 11 people)
  • 30-39: 46.0% - (6 of 13 people)
  • 40-49: 52.0% - (9 of 17 people)
  • 50-59: 16.0% - (1 of 6 people)
  • 60+: 0.0% - (0 of 4 people)
Ibuprofen:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 2 people)
  • 20-29: 18.0% - (2 of 11 people)
  • 30-39: 16.0% - (2 of 12 people)
  • 40-49: 18.0% - (3 of 16 people)
  • 50-59: 16.0% - (1 of 6 people)
  • 60+: 50.0% - (2 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • delirium
  • asthma
  • hair - oily
  • menstrual cycle prolonged
  • migraine with aura
  • migraine without aura
  • oily skin
  • seborrhoeic dermatitis
  • visual disturbance
  • suicide attempt
1 - 6 months:
  • pulmonary embolism
  • anxiety
  • fall
  • gastrooesophageal reflux disease
  • pain
  • weight increased
  • cleft palate
  • craniosynostosis
  • developmental delay
  • dizziness
6 - 12 months:
  • bone marrow depression
  • headache
  • nausea
  • benign intracranial hypertension
  • bone and joint pain
  • csf pressure increased
  • diabetes mellitus
  • dysaesthesia
  • glucose tolerance impaired
  • haemoglobin decreased
1 - 2 years:
  • deep vein thrombosis
  • pulmonary embolism
  • nausea
  • oedema peripheral
  • abdominal pain
  • chills
  • cholelithiasis
  • confusion
  • eye twitch
  • fatigue
2 - 5 years:
  • anxiety
  • pain
  • emotional distress
  • bipolar disorder
  • blood iron decreased
  • cholecystitis chronic
  • major depression
  • pneumonia
  • somnolence
  • suicidal ideation
5 - 10 years:
  • anxiety
  • pain
  • pneumonia
  • pulmonary embolism
  • emotional distress
  • bipolar disorder
  • tachycardia
  • cholecystitis acute
  • cholelithiasis
  • injury
10+ years:
  • constipation aggravated
  • abdominal bloating
  • aphasia - primary progressive
  • apraxia
  • burping
  • confusional state
  • cyclic vomiting syndrome
  • deep vein thrombosis
  • dysphagia aggravated
  • migraine aggravated
not specified:
  • pain
  • headache
  • nausea
  • deep vein thrombosis
  • anxiety
  • dizziness
  • fatigue
  • vomiting
  • pulmonary embolism
  • depression

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • headache
  • anxiety
  • deep vein thrombosis
  • pulmonary embolism
  • depression
  • vomiting
  • migraine
  • dizziness
male:
  • hypoaesthesia
  • headache
  • pneumonia
  • sinusitis
  • neck pain
  • cough
  • emotional disorder
  • cleft palate
  • craniosynostosis
  • deafness

Most common drug interactions by age *:

2-9:
  • convulsion
  • drug ineffective
  • haematemesis
  • inappropriate antidiuretic hormone secretion
  • coma
  • depressed level of consciousness
  • pneumonia
  • pyrexia
  • discomfort
  • feeding disorder neonatal
10-19:
  • convulsion
  • deep vein thrombosis
  • headache
  • cholecystitis chronic
  • dizziness
  • gallbladder disorder
  • migraine
  • psychotic disorder
  • pulmonary embolism
  • anticonvulsant drug level decreased
20-29:
  • pain
  • cholecystitis chronic
  • deep vein thrombosis
  • gallbladder disorder
  • pulmonary embolism
  • anxiety
  • injury
  • abdominal pain
  • depression
  • vomiting
30-39:
  • pain
  • pulmonary embolism
  • headache
  • nausea
  • cholelithiasis
  • deep vein thrombosis
  • depression
  • suicidal ideation
  • cholecystitis chronic
  • anxiety
40-49:
  • pain
  • headache
  • nausea
  • anxiety
  • deep vein thrombosis
  • diabetes mellitus
  • vomiting
  • oedema peripheral
  • pulmonary embolism
  • back pain
50-59:
  • headache
  • nausea
  • hypoaesthesia
  • fatigue
  • dizziness
  • neck pain
  • fall
  • emotional disorder
  • gastric perforation
  • kidney infection
60+:
  • vision blurred
  • pain
  • headache
  • nausea
  • anxiety
  • loss of consciousness
  • scar
  • toothache
  • vertigo
  • vomiting

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Topamax (topiramate) is often used to treat migraine. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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