Review: taking Topamax and Ibuprofen together


Summary

Drug interactions are reported among people who take Topamax and Ibuprofen together. This review analyzes the effectiveness and drug interactions between Topamax and Ibuprofen. It is created by eHealthMe based on reports of 1,894 people who take the same drugs from FDA and social media, and is updated regularly.

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Topamax

Topamax has active ingredients of topiramate. It is often used in migraine. (latest outcomes from Topamax 34,483 users)

Ibuprofen

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from Ibuprofen 92,738 users)

On Sep, 16, 2016

1,894 people who take Topamax, Ibuprofen are studied.


Number of reports submitted per year:

Topamax and Ibuprofen drug interactions.

Drug effectiveness over time:

Topamax:
  • < 1 month: 66.0% - (2 of 3 people)
  • 1 - 6 months: 46.0% - (7 of 15 people)
  • 6 - 12 months: 0.0% - (0 of 2 people)
  • 1 - 2 years: 14.0% - (1 of 7 people)
  • 2 - 5 years: 0.0% - (0 of 4 people)
  • 5 - 10 years: 100.0% - (7 of 7 people)
  • 10+ years: 50.0% - (2 of 4 people)
  • not specified: 33.0% - (1 of 3 people)
Ibuprofen:
  • < 1 month: 33.0% - (2 of 6 people)
  • 1 - 6 months: 33.0% - (1 of 3 people)
  • 6 - 12 months: 0.0% - (0 of 6 people)
  • 1 - 2 years: 0.0% - (0 of 4 people)
  • 2 - 5 years: 0.0% - (0 of 2 people)
  • 5 - 10 years: 40.0% - (2 of 5 people)
  • 10+ years: 0.0% - (0 of 12 people)
  • not specified: 60.0% - (3 of 5 people)

Drug effectiveness by gender:

Topamax:
  • female: 45.0% - (20 of 44 people)
  • male: 0.0% - (0 of 1 people)
Ibuprofen:
  • female: 19.0% - (8 of 42 people)
  • male: 0.0% - (0 of 1 people)

Drug effectiveness by age:

Topamax:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 50.0% - (1 of 2 people)
  • 20-29: 55.0% - (5 of 9 people)
  • 30-39: 45.0% - (5 of 11 people)
  • 40-49: 53.0% - (8 of 15 people)
  • 50-59: 16.0% - (1 of 6 people)
  • 60+: 0.0% - (0 of 2 people)
Ibuprofen:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 2 people)
  • 20-29: 11.0% - (1 of 9 people)
  • 30-39: 20.0% - (2 of 10 people)
  • 40-49: 21.0% - (3 of 14 people)
  • 50-59: 16.0% - (1 of 6 people)
  • 60+: 50.0% - (1 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • delirium
  • pneumonia
  • tremor
  • pain
  • asthma
  • chest pain
  • dysgeusia
  • dyspnoea
  • hair - oily
  • hepatic enzyme increased
1 - 6 months:
  • emotional disorder
  • anxiety
  • cleft palate
  • suicidal ideation
  • cardiac murmur
  • migraine
  • attention deficit/hyperactivity disorder
  • cardiac valve disease
  • cleft lip
  • ear disorder
6 - 12 months:
  • bone marrow depression
  • emotional disorder
  • headache
  • nausea
  • anxiety
  • asthma
  • benign intracranial hypertension
  • bipolar i disorder
  • bone and joint pain
  • chest pain
1 - 2 years:
  • deep vein thrombosis
  • pulmonary embolism
  • fatigue
  • pain
  • anxiety
  • calculus ureteric
  • dyspnoea
  • metabolic acidosis
  • nausea
  • oedema peripheral
2 - 5 years:
  • anxiety
  • pain
  • emotional distress
  • major depression
  • cholecystitis chronic
  • bipolar disorder
  • blood iron decreased
  • emotional disorder
  • pneumonia
  • somnolence
5 - 10 years:
  • anxiety
  • pain
  • pneumonia
  • pulmonary embolism
  • emotional distress
  • bipolar disorder
  • tachycardia
  • cholecystitis acute
  • cholelithiasis
  • injury
10+ years:
  • constipation aggravated
  • abdominal bloating
  • aphasia - primary progressive
  • apraxia
  • burping
  • confusional state
  • cyclic vomiting syndrome
  • deep vein thrombosis
  • dysphagia aggravated
  • migraine aggravated
not specified:
  • pain
  • headache
  • nausea
  • anxiety
  • fatigue
  • depression
  • deep vein thrombosis
  • migraine
  • pulmonary embolism
  • injury

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • headache
  • anxiety
  • depression
  • fatigue
  • pulmonary embolism
  • migraine
  • deep vein thrombosis
  • injury
male:
  • emotional disorder
  • headache
  • cleft palate
  • pain
  • pneumonia
  • vomiting
  • hypoaesthesia
  • foetal exposure during pregnancy
  • cough
  • nausea

Most common drug interactions by age *:

0-1:
  • pain
  • decreased appetite
  • hyponatraemia
  • myoclonic epilepsy
  • vomiting
  • constipation
  • diabetes insipidus
  • muscle spasms
  • foetal exposure during pregnancy
  • dehydration
2-9:
  • convulsion
  • drug ineffective
  • haematemesis
  • inappropriate antidiuretic hormone secretion
  • coma
  • decreased activity
  • depressed level of consciousness
  • pneumonia
  • pyrexia
  • discomfort
10-19:
  • convulsion
  • pain
  • headache
  • psychotic disorder
  • deep vein thrombosis
  • migraine
  • pyrexia
  • pulmonary embolism
  • nausea
  • dizziness
20-29:
  • pain
  • deep vein thrombosis
  • anxiety
  • injury
  • cholecystitis chronic
  • pulmonary embolism
  • gallbladder disorder
  • abdominal pain
  • depression
  • emotional distress
30-39:
  • pain
  • headache
  • pulmonary embolism
  • anxiety
  • injury
  • deep vein thrombosis
  • nausea
  • emotional distress
  • depression
  • cholelithiasis
40-49:
  • pain
  • nausea
  • anxiety
  • headache
  • migraine
  • insomnia
  • deep vein thrombosis
  • suicidal ideation
  • type 2 diabetes mellitus
  • vomiting
50-59:
  • nausea
  • headache
  • fatigue
  • fall
  • hypoaesthesia
  • dizziness
  • pain
  • drug ineffective
  • emotional disorder
  • malaise
60+:
  • fatigue
  • pain
  • haemorrhage
  • nausea
  • abdominal distension
  • abdominal pain
  • white blood cell count increased
  • abdominal tenderness
  • back disorder
  • dyspepsia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Topamax (topiramate) is often used to treat migraine. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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