Review: taking Topamax and Norco together


Summary

Drug interactions are reported among people who take Topamax and Norco together. This review analyzes the effectiveness and drug interactions between Topamax and Norco. It is created by eHealthMe based on reports of 1,544 people who take the same drugs from FDA and social media, and is updated regularly.

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Topamax

Topamax has active ingredients of topiramate. It is often used in migraine. (latest outcomes from Topamax 24,312 users)

Norco

Norco has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. (latest outcomes from Norco 6,733 users)

On Jul, 27, 2016

1,544 people who take Topamax, Norco are studied.


Number of reports submitted per year:

Topamax and Norco drug interactions.

Drug effectiveness over time:

Topamax:
  • < 1 month: 23.0% - (3 of 13 people)
  • 1 - 6 months: 18.0% - (6 of 32 people)
  • 6 - 12 months: 47.0% - (10 of 21 people)
  • 1 - 2 years: 53.0% - (8 of 15 people)
  • 2 - 5 years: 45.0% - (20 of 44 people)
  • 5 - 10 years: 63.0% - (14 of 22 people)
  • 10+ years: 40.0% - (6 of 15 people)
  • not specified: 50.0% - (1 of 2 people)
Norco:
  • < 1 month: 28.0% - (7 of 25 people)
  • 1 - 6 months: 33.0% - (5 of 15 people)
  • 6 - 12 months: 45.0% - (5 of 11 people)
  • 1 - 2 years: 43.0% - (13 of 30 people)
  • 2 - 5 years: 56.0% - (26 of 46 people)
  • 5 - 10 years: 30.0% - (7 of 23 people)
  • 10+ years: 35.0% - (6 of 17 people)
  • not specified: 33.0% - (1 of 3 people)

Drug effectiveness by gender:

Topamax:
  • female: 43.0% - (64 of 147 people)
  • male: 23.0% - (4 of 17 people)
Norco:
  • female: 42.0% - (65 of 153 people)
  • male: 29.0% - (5 of 17 people)

Drug effectiveness by age:

Topamax:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 50.0% - (1 of 2 people)
  • 20-29: 33.0% - (6 of 18 people)
  • 30-39: 38.0% - (24 of 62 people)
  • 40-49: 47.0% - (21 of 44 people)
  • 50-59: 48.0% - (16 of 33 people)
  • 60+: 0.0% - (0 of 5 people)
Norco:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 2 people)
  • 20-29: 50.0% - (9 of 18 people)
  • 30-39: 52.0% - (34 of 65 people)
  • 40-49: 26.0% - (12 of 46 people)
  • 50-59: 42.0% - (15 of 35 people)
  • 60+: 0.0% - (0 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • depression
  • pain
  • confusional state
  • drug ineffective
  • agitation
  • dyspnoea
  • feeling abnormal
  • headache
  • injury
  • memory impairment
1 - 6 months:
  • depression
  • headache
  • pain
  • nausea
  • anxiety
  • gastrooesophageal reflux disease
  • balance disorder
  • chest pain
  • drug abuse
  • fall
6 - 12 months:
  • fatigue
  • weight increased
  • anaemia
  • calculus urethral
  • complications of transplanted kidney
  • confusional state
  • dyspnoea
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • flank pain
  • obstruction gastric
1 - 2 years:
  • depression
  • memory impairment
  • anxiety
  • blood alkaline phosphatase increased
  • cancer
  • confusional state
  • dyspnoea
  • insomnia
  • paraesthesia
  • pulmonary embolism
2 - 5 years:
  • anxiety disorder
  • fibromyalgia
  • menopause
  • migraine with aura
  • pain
  • vertigo
  • chest pain
  • depression
  • memory impairment
  • back pain
5 - 10 years:
  • depression
  • dizziness
  • fumbling
  • lack of strength, muscle weakness, weakness
  • loss of hearing
  • low back pain
  • muscle pain
  • nerve pain
  • noises or buzzing in the ears
  • numbness in hands or feet
10+ years:
  • blue toe syndrome
  • cold intolerance
  • muscle weakness
  • numbness and tingling
  • painful response to normal stimuli
  • deep vein thrombosis
  • pulmonary embolism
  • dizziness postural
  • constipation aggravated
  • exhaustion, fatigue, lethargy, tiredness, weariness
not specified:
  • pain
  • nausea
  • headache
  • depression
  • anxiety
  • vomiting
  • dyspnoea
  • fatigue
  • back pain
  • insomnia

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • depression
  • headache
  • anxiety
  • migraine
  • vomiting
  • fatigue
  • weight increased
  • oedema peripheral
male:
  • headache
  • pain
  • depression
  • nausea
  • insomnia
  • drug dependence
  • anxiety
  • suicidal ideation
  • confusional state
  • drug ineffective

Most common drug interactions by age *:

0-1:
  • death
  • foetal exposure during pregnancy
  • deep vein thrombosis
  • diabetic complication
  • neuroleptic malignant syndrome
  • pancreatitis
  • pancreatitis chronic
  • pulmonary embolism
  • suicide attempt
  • systemic lupus erythematosus
10-19:
  • pain
  • nephrogenic systemic fibrosis
  • cholecystitis chronic
  • cardiac arrest
  • anxiety
  • emotional distress
  • fibrosis
  • metaplasia
  • mobility decreased
  • myocardial fibrosis
20-29:
  • pain
  • depression
  • injury
  • anxiety
  • cholecystitis chronic
  • deep vein thrombosis
  • pulmonary embolism
  • dyspnoea
  • migraine
  • emotional distress
30-39:
  • pain
  • headache
  • nausea
  • vomiting
  • depression
  • migraine
  • paraesthesia
  • suicidal ideation
  • deep vein thrombosis
  • weight increased
40-49:
  • headache
  • nausea
  • depression
  • pain
  • fatigue
  • back pain
  • insomnia
  • vomiting
  • anxiety
  • drug dependence
50-59:
  • pain
  • headache
  • dyspnoea
  • fatigue
  • chest pain
  • dizziness
  • fall
  • nausea
  • weight decreased
  • weight increased
60+:
  • pain
  • myocardial infarction
  • asthenia
  • pneumonia
  • nausea
  • dyspnoea
  • oedema peripheral
  • convulsion
  • fall
  • diarrhoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Topamax (topiramate) is often used to treat migraine. Norco (acetaminophen; hydrocodone bitartrate) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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