Review: taking Topamax and Norco together


Summary

Drug interactions are reported among people who take Topamax and Norco together. This review analyzes the effectiveness and drug interactions between Topamax and Norco. It is created by eHealthMe based on reports of 2,524 people who take the same drugs from FDA and social media, and is updated regularly.

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Topamax

Topamax has active ingredients of topiramate. It is often used in migraine. (latest outcomes from Topamax 34,483 users)

Norco

Norco has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. (latest outcomes from Norco 16,353 users)

On Sep, 17, 2016

2,524 people who take Topamax, Norco are studied.


Number of reports submitted per year:

Topamax and Norco drug interactions.

Drug effectiveness over time:

Topamax:
  • < 1 month: 27.0% - (3 of 11 people)
  • 1 - 6 months: 23.0% - (6 of 26 people)
  • 6 - 12 months: 50.0% - (10 of 20 people)
  • 1 - 2 years: 53.0% - (7 of 13 people)
  • 2 - 5 years: 50.0% - (17 of 34 people)
  • 5 - 10 years: 58.0% - (10 of 17 people)
  • 10+ years: 46.0% - (6 of 13 people)
  • not specified: 50.0% - (1 of 2 people)
Norco:
  • < 1 month: 29.0% - (7 of 24 people)
  • 1 - 6 months: 33.0% - (5 of 15 people)
  • 6 - 12 months: 40.0% - (4 of 10 people)
  • 1 - 2 years: 40.0% - (10 of 25 people)
  • 2 - 5 years: 51.0% - (16 of 31 people)
  • 5 - 10 years: 26.0% - (5 of 19 people)
  • 10+ years: 35.0% - (5 of 14 people)
  • not specified: 33.0% - (1 of 3 people)

Drug effectiveness by gender:

Topamax:
  • female: 46.0% - (56 of 121 people)
  • male: 26.0% - (4 of 15 people)
Norco:
  • female: 39.0% - (50 of 126 people)
  • male: 20.0% - (3 of 15 people)

Drug effectiveness by age:

Topamax:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 35.0% - (6 of 17 people)
  • 30-39: 43.0% - (20 of 46 people)
  • 40-49: 48.0% - (19 of 39 people)
  • 50-59: 50.0% - (14 of 28 people)
  • 60+: 0.0% - (0 of 5 people)
Norco:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 47.0% - (8 of 17 people)
  • 30-39: 46.0% - (22 of 47 people)
  • 40-49: 26.0% - (11 of 42 people)
  • 50-59: 40.0% - (12 of 30 people)
  • 60+: 0.0% - (0 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • depression
  • drug ineffective
  • pain
  • confusional state
  • dyspnoea
  • headache
  • insomnia
  • weight decreased
  • emotional distress
  • premature baby
1 - 6 months:
  • depression
  • headache
  • pain
  • migraine
  • pulmonary embolism
  • anxiety
  • gastrooesophageal reflux disease
  • nausea
  • convulsion
  • vomiting
6 - 12 months:
  • back disorder
  • fatigue
  • migraine
  • nausea
  • pain
  • weight increased
  • acute hepatic failure
  • anaemia
  • calculus urethral
  • complications of transplanted kidney
1 - 2 years:
  • depression
  • anxiety
  • maternal exposure during pregnancy
  • paraesthesia
  • memory impairment
  • atrial septal defect
  • congenital anomaly
  • drug ineffective
  • migraine
  • patent ductus arteriosus
2 - 5 years:
  • pain
  • anxiety disorder
  • chest pain
  • fibromyalgia
  • menopause
  • migraine with aura
  • vertigo
  • depression
  • memory impairment
  • anxiety
5 - 10 years:
  • depression
  • dizziness
  • fumbling
  • lack of strength, muscle weakness, weakness
  • loss of hearing
  • low back pain
  • muscle pain
  • nerve pain
  • noises or buzzing in the ears
  • numbness in hands or feet
10+ years:
  • blue toe syndrome
  • cold intolerance
  • muscle weakness
  • numbness and tingling
  • painful response to normal stimuli
  • deep vein thrombosis
  • pulmonary embolism
  • dizziness postural
  • autoimmune thyroiditis
  • constipation aggravated
not specified:
  • pain
  • nausea
  • headache
  • depression
  • fatigue
  • anxiety
  • dyspnoea
  • vomiting
  • migraine
  • fall

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • headache
  • depression
  • anxiety
  • fatigue
  • migraine
  • vomiting
  • fall
  • dyspnoea
male:
  • pain
  • depression
  • headache
  • nausea
  • anxiety
  • insomnia
  • drug ineffective
  • suicidal ideation
  • drug dependence
  • dyspnoea

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • premature baby
  • talipes
  • atrial septal defect
  • cardiomyopathy
  • emotional distress
  • left ventricular hypertrophy
  • low birth weight baby
  • mitral valve incompetence
  • pulmonary artery stenosis
2-9:
  • death
  • atrial septal defect
  • cardio-respiratory arrest
  • cholelithiasis
  • congenital tricuspid valve atresia
  • congenital tricuspid valve stenosis
  • enterocolitis
  • factor vii deficiency
  • failure to thrive
  • foetal exposure during pregnancy
10-19:
  • pain
  • nephrogenic systemic fibrosis
  • cholecystitis chronic
  • cardiac arrest
  • anxiety
  • emotional distress
  • pulmonary embolism
  • fibrosis
  • metaplasia
  • mobility decreased
20-29:
  • pain
  • deep vein thrombosis
  • injury
  • pulmonary embolism
  • depression
  • dyspnoea
  • anxiety
  • cholecystitis chronic
  • emotional distress
  • migraine
30-39:
  • pain
  • nausea
  • headache
  • pulmonary embolism
  • vomiting
  • deep vein thrombosis
  • depression
  • anxiety
  • migraine
  • injury
40-49:
  • nausea
  • pain
  • headache
  • depression
  • fatigue
  • vomiting
  • back pain
  • fall
  • insomnia
  • anxiety
50-59:
  • pain
  • fatigue
  • headache
  • fall
  • nausea
  • weight decreased
  • malaise
  • drug ineffective
  • migraine
  • vomiting
60+:
  • pain
  • headache
  • nausea
  • diarrhoea
  • dyspnoea
  • asthenia
  • pneumonia
  • vomiting
  • myocardial infarction
  • fall

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Topamax (topiramate) is often used to treat migraine. Norco (acetaminophen; hydrocodone bitartrate) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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