Review: taking Topamax and Norco together


Summary

Drug interactions are reported among people who take Topamax and Norco together. This review analyzes the effectiveness and drug interactions between Topamax and Norco. It is created by eHealthMe based on reports of 1,972 people who take the same drugs from FDA and social media, and is updated regularly.

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Topamax

Topamax has active ingredients of topiramate. It is often used in migraine. (latest outcomes from Topamax 28,047 users)

Norco

Norco has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. (latest outcomes from Norco 9,270 users)

On Aug, 26, 2016

1,972 people who take Topamax, Norco are studied.


Number of reports submitted per year:

Topamax and Norco drug interactions.

Drug effectiveness over time:

Topamax:
  • < 1 month: 30.0% - (3 of 10 people)
  • 1 - 6 months: 23.0% - (6 of 26 people)
  • 6 - 12 months: 45.0% - (9 of 20 people)
  • 1 - 2 years: 53.0% - (7 of 13 people)
  • 2 - 5 years: 50.0% - (17 of 34 people)
  • 5 - 10 years: 58.0% - (10 of 17 people)
  • 10+ years: 46.0% - (6 of 13 people)
  • not specified: 50.0% - (1 of 2 people)
Norco:
  • < 1 month: 29.0% - (7 of 24 people)
  • 1 - 6 months: 33.0% - (5 of 15 people)
  • 6 - 12 months: 40.0% - (4 of 10 people)
  • 1 - 2 years: 40.0% - (10 of 25 people)
  • 2 - 5 years: 51.0% - (16 of 31 people)
  • 5 - 10 years: 26.0% - (5 of 19 people)
  • 10+ years: 35.0% - (5 of 14 people)
  • not specified: 33.0% - (1 of 3 people)

Drug effectiveness by gender:

Topamax:
  • female: 45.0% - (55 of 120 people)
  • male: 26.0% - (4 of 15 people)
Norco:
  • female: 39.0% - (50 of 126 people)
  • male: 20.0% - (3 of 15 people)

Drug effectiveness by age:

Topamax:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 50.0% - (1 of 2 people)
  • 20-29: 31.0% - (5 of 16 people)
  • 30-39: 43.0% - (20 of 46 people)
  • 40-49: 48.0% - (19 of 39 people)
  • 50-59: 50.0% - (14 of 28 people)
  • 60+: 0.0% - (0 of 4 people)
Norco:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 2 people)
  • 20-29: 50.0% - (8 of 16 people)
  • 30-39: 46.0% - (22 of 47 people)
  • 40-49: 26.0% - (11 of 42 people)
  • 50-59: 40.0% - (12 of 30 people)
  • 60+: 0.0% - (0 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • depression
  • drug ineffective
  • pain
  • confusional state
  • dyspnoea
  • emotional distress
  • headache
  • agitation
  • anxiety
  • feeling abnormal
1 - 6 months:
  • depression
  • headache
  • pain
  • pulmonary embolism
  • anxiety
  • gastrooesophageal reflux disease
  • nausea
  • convulsion
  • vomiting
  • abdominal pain
6 - 12 months:
  • fatigue
  • pain
  • weight increased
  • anaemia
  • calculus urethral
  • complications of transplanted kidney
  • confusional state
  • decreased appetite
  • depression
  • diarrhoea
1 - 2 years:
  • depression
  • anxiety
  • paraesthesia
  • memory impairment
  • drug ineffective
  • migraine
  • arthralgia
  • blood alkaline phosphatase increased
  • cancer
  • confusional state
2 - 5 years:
  • pain
  • anxiety disorder
  • chest pain
  • fibromyalgia
  • menopause
  • migraine with aura
  • vertigo
  • depression
  • memory impairment
  • anxiety
5 - 10 years:
  • depression
  • dizziness
  • fumbling
  • lack of strength, muscle weakness, weakness
  • loss of hearing
  • low back pain
  • muscle pain
  • nerve pain
  • noises or buzzing in the ears
  • numbness in hands or feet
10+ years:
  • blue toe syndrome
  • cold intolerance
  • muscle weakness
  • numbness and tingling
  • painful response to normal stimuli
  • deep vein thrombosis
  • pulmonary embolism
  • dizziness postural
  • constipation aggravated
  • exhaustion, fatigue, lethargy, tiredness, weariness
not specified:
  • pain
  • nausea
  • headache
  • depression
  • fatigue
  • anxiety
  • dyspnoea
  • vomiting
  • back pain
  • deep vein thrombosis

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • depression
  • headache
  • anxiety
  • fatigue
  • migraine
  • vomiting
  • deep vein thrombosis
  • fall
male:
  • pain
  • headache
  • depression
  • nausea
  • anxiety
  • insomnia
  • drug dependence
  • suicidal ideation
  • drug ineffective
  • paraesthesia

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • premature baby
  • talipes
  • atrial septal defect
  • cardiomyopathy
  • emotional distress
  • left ventricular hypertrophy
  • low birth weight baby
  • mitral valve incompetence
  • pulmonary artery stenosis
2-9:
  • death
  • atrial septal defect
  • cardio-respiratory arrest
  • cholelithiasis
  • congenital tricuspid valve atresia
  • congenital tricuspid valve stenosis
  • enterocolitis
  • factor vii deficiency
  • failure to thrive
  • foetal exposure during pregnancy
10-19:
  • pain
  • nephrogenic systemic fibrosis
  • cholecystitis chronic
  • cardiac arrest
  • anxiety
  • emotional distress
  • fibrosis
  • metaplasia
  • mobility decreased
  • myocardial fibrosis
20-29:
  • pain
  • deep vein thrombosis
  • injury
  • pulmonary embolism
  • cholecystitis chronic
  • depression
  • anxiety
  • dyspnoea
  • migraine
  • emotional distress
30-39:
  • pain
  • headache
  • deep vein thrombosis
  • nausea
  • pulmonary embolism
  • depression
  • injury
  • completed suicide
  • vomiting
  • migraine
40-49:
  • nausea
  • pain
  • headache
  • depression
  • fatigue
  • back pain
  • vomiting
  • fall
  • insomnia
  • migraine
50-59:
  • pain
  • fatigue
  • headache
  • nausea
  • fall
  • weight decreased
  • dyspnoea
  • malaise
  • drug ineffective
  • vomiting
60+:
  • pain
  • nausea
  • diarrhoea
  • dyspnoea
  • pneumonia
  • myocardial infarction
  • asthenia
  • completed suicide
  • vomiting
  • anxiety

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Topamax (topiramate) is often used to treat migraine. Norco (acetaminophen; hydrocodone bitartrate) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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