Review: taking Tramadol hydrochloride and Codeine sulfate together


Summary

Drug interactions are reported among people who take Tramadol hydrochloride and Codeine sulfate together. This review analyzes the effectiveness and drug interactions between Tramadol hydrochloride and Codeine sulfate. It is created by eHealthMe based on reports of 184 people who take the same drugs from FDA and social media, and is updated regularly.

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Tramadol Hydrochloride

Tramadol hydrochloride has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol hydrochloride 6,089 users)

Codeine Sulfate

Codeine sulfate has active ingredients of codeine sulfate. It is often used in pain. (latest outcomes from Codeine sulfate 2,024 users)

On Jul, 29, 2016

184 people who take Tramadol Hydrochloride, Codeine Sulfate are studied.


Number of reports submitted per year:

Tramadol hydrochloride and Codeine sulfate drug interactions.

Drug effectiveness over time:

Tramadol Hydrochloride:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 100.0% - (1 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 50.0% - (1 of 2 people)
  • 2 - 5 years: 0.0% - (0 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Codeine Sulfate:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 50.0% - (1 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 33.0% - (1 of 3 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Tramadol Hydrochloride:
  • female: 25.0% - (1 of 4 people)
  • male: 50.0% - (1 of 2 people)
Codeine Sulfate:
  • female: 25.0% - (1 of 4 people)
  • male: 33.0% - (1 of 3 people)

Drug effectiveness by age:

Tramadol Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 0.0% - (0 of 2 people)
  • 60+: 0.0% - (0 of 1 people)
Codeine Sulfate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 0.0% - (0 of 2 people)
  • 60+: 0.0% - (0 of 1 people)

Most common drug interactions over time *:

< 1 month:
  • neutropenia
  • pneumonia
  • hyperbilirubinaemia
  • thrombocytopenia
  • convulsion
  • dyskinesia
  • jaundice cholestatic
  • muscle rigidity
  • syncope
  • malaise
1 - 6 months:
  • gait disturbance
  • balance disorder
  • agitation
  • anxiety
  • arthralgia
  • blood sodium decreased
  • cogwheel rigidity
  • contusion
  • convulsion
  • delirium
1 - 2 years:
  • acid reflux
  • balance disorder
  • gait disturbance
  • joint range of motion decreased
  • joint stiffness
  • joint swelling
  • liver function test abnormal
  • muscle contracture
  • muscle tightness
  • musculoskeletal stiffness
2 - 5 years:
  • agitation
  • anxiety
  • arthralgia
  • blood sodium decreased
  • cogwheel rigidity
  • contusion
  • convulsion
  • delirium
  • depression
  • dizziness
not specified:
  • dyspnoea
  • vomiting
  • arthralgia
  • anxiety
  • serotonin syndrome
  • pruritus
  • depression
  • dizziness
  • malaise
  • hyperhidrosis

Most common drug interactions by gender *:

female:
  • vomiting
  • arthralgia
  • serotonin syndrome
  • anxiety
  • dizziness
  • dyspnoea
  • pruritus
  • malaise
  • hyperhidrosis
  • asthenia
male:
  • pneumonia
  • dyspnoea
  • depression
  • neutropenia
  • anxiety
  • drug toxicity
  • malaise
  • tremor
  • back pain
  • convulsion

Most common drug interactions by age *:

20-29:
  • convulsion
  • dizziness
  • dyskinesia
  • anxiety
  • dyspnoea
  • headache
  • malaise
  • pruritus
  • balance disorder
  • depression
30-39:
  • serotonin syndrome
  • arthralgia
  • blood sodium decreased
  • contusion
  • headache
  • malaise
  • nightmare
  • sleep disorder
  • suicidal ideation
  • visual impairment
40-49:
  • serotonin syndrome
  • pain
  • skin burning sensation
  • arthralgia
  • hypersensitivity
  • myalgia
  • pruritus
  • brain oedema
  • pulmonary oedema
  • fatigue
50-59:
  • bacterial sepsis
  • completed suicide
  • depression
  • drug level increased
  • encephalitis
  • multiple drug overdose
  • activated partial thromboplastin time prolonged
  • blood albumin decreased
  • blood alkaline phosphatase increased
  • blood fibrinogen increased
60+:
  • back pain
  • vomiting
  • pain
  • dizziness
  • drug hypersensitivity
  • dyspnoea
  • fatigue
  • gait disturbance
  • neutropenia
  • osteoarthritis

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Tramadol hydrochloride and Codeine sulfate?

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On eHealthMe, Tramadol hydrochloride (tramadol hydrochloride) is often used to treat pain. Codeine sulfate (codeine sulfate) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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