Review: taking Tramadol hydrochloride and Gabapentin together


Summary

Drug interactions are reported among people who take Tramadol hydrochloride and Gabapentin together. This review analyzes the effectiveness and drug interactions between Tramadol hydrochloride and Gabapentin. It is created by eHealthMe based on reports of 7,290 people who take the same drugs from FDA and social media, and is updated regularly.

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Tramadol Hydrochloride

Tramadol hydrochloride has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol hydrochloride 7,655 users)

Gabapentin

Gabapentin has active ingredients of gabapentin. It is often used in pain. (latest outcomes from Gabapentin 52,972 users)

On Aug, 27, 2016

7,290 people who take Tramadol Hydrochloride, Gabapentin are studied.


Number of reports submitted per year:

Tramadol hydrochloride and Gabapentin drug interactions.

Drug effectiveness over time:

Tramadol Hydrochloride:
  • < 1 month: 9.0% - (2 of 22 people)
  • 1 - 6 months: 14.0% - (9 of 61 people)
  • 6 - 12 months: 21.0% - (10 of 47 people)
  • 1 - 2 years: 22.0% - (18 of 79 people)
  • 2 - 5 years: 27.0% - (17 of 61 people)
  • 5 - 10 years: 31.0% - (10 of 32 people)
  • 10+ years: 66.0% - (6 of 9 people)
  • not specified: 20.0% - (1 of 5 people)
Gabapentin:
  • < 1 month: 20.0% - (6 of 29 people)
  • 1 - 6 months: 16.0% - (13 of 80 people)
  • 6 - 12 months: 18.0% - (9 of 49 people)
  • 1 - 2 years: 26.0% - (14 of 52 people)
  • 2 - 5 years: 25.0% - (20 of 77 people)
  • 5 - 10 years: 50.0% - (12 of 24 people)
  • 10+ years: 50.0% - (5 of 10 people)
  • not specified: 25.0% - (1 of 4 people)

Drug effectiveness by gender:

Tramadol Hydrochloride:
  • female: 23.0% - (55 of 234 people)
  • male: 21.0% - (18 of 82 people)
Gabapentin:
  • female: 27.0% - (68 of 243 people)
  • male: 14.0% - (12 of 82 people)

Drug effectiveness by age:

Tramadol Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 50.0% - (1 of 2 people)
  • 20-29: 18.0% - (6 of 32 people)
  • 30-39: 18.0% - (10 of 53 people)
  • 40-49: 23.0% - (22 of 92 people)
  • 50-59: 19.0% - (15 of 77 people)
  • 60+: 31.0% - (19 of 60 people)
Gabapentin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (2 of 2 people)
  • 20-29: 18.0% - (6 of 32 people)
  • 30-39: 25.0% - (14 of 55 people)
  • 40-49: 29.0% - (28 of 96 people)
  • 50-59: 22.0% - (18 of 79 people)
  • 60+: 19.0% - (12 of 61 people)

Most common drug interactions over time *:

< 1 month:
  • confusional state
  • somnolence
  • nausea
  • peripheral motor neuropathy
  • drug ineffective
  • hallucination
  • headache
  • vomiting
  • dizziness
  • malaise
1 - 6 months:
  • confusional state
  • pain
  • nausea
  • depression
  • dizziness
  • drug ineffective
  • fatigue
  • disorientation
  • loss of consciousness
  • vasculitic rash
6 - 12 months:
  • depression
  • dizziness
  • dehydration
  • nausea
  • insomnia
  • disorientation
  • loss of consciousness
  • mental status changes
  • muscle twitching
  • bone pain
1 - 2 years:
  • dizziness
  • pain
  • depression
  • chest pain
  • muscle weakness
  • drug ineffective
  • fatigue
  • malaise
  • anxiety
  • leg pain
2 - 5 years:
  • anxiety
  • depression
  • fatigue
  • suicide attempt
  • chronic pain
  • neuropathy
  • chest pain
  • dizziness
  • drug ineffective
  • pain
5 - 10 years:
  • convulsion
  • accidental overdose
  • drug withdrawal syndrome
  • loss of consciousness
  • feeling of body temperature change
  • retching
  • cerebrovascular accident
  • hypoaesthesia
  • inflammatory pain
  • swelling
10+ years:
  • headache
  • insomnia
  • anger
  • anxiety
  • depression
  • dry hair
  • hair thinning
  • irritability
  • restless leg syndrome
  • short-term memory loss
not specified:
  • pain
  • nausea
  • anxiety
  • fatigue
  • dyspnoea
  • depression
  • back pain
  • fall
  • headache
  • drug ineffective

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • fatigue
  • anxiety
  • headache
  • dyspnoea
  • fall
  • pain in extremity
  • depression
  • drug ineffective
male:
  • pain
  • depression
  • anxiety
  • dizziness
  • drug ineffective
  • back pain
  • nausea
  • dyspnoea
  • fatigue
  • fall

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • premature baby
  • type 2 diabetes mellitus
  • blood cholesterol increased
  • blood triglycerides increased
  • chest pain
  • diabetes mellitus
  • encephalopathy
  • haematoma
  • hyperammonaemia
2-9:
  • infection
  • chills
  • convulsion
  • diarrhoea
  • febrile neutropenia
  • hypertonia
  • hypoventilation
  • mucosal inflammation
  • mydriasis
  • overdose
10-19:
  • confusional state
  • flushing
  • rash
  • tremor
  • hallucination, visual
  • headache
  • suicidal ideation
  • emotional distress
  • vomiting
  • febrile neutropenia
20-29:
  • pain
  • insomnia
  • fatigue
  • dizziness
  • abdominal distension
  • depression
  • injury
  • alopecia
  • anxiety
  • headache
30-39:
  • depression
  • anxiety
  • headache
  • dizziness
  • drug ineffective
  • nausea
  • dyspnoea
  • drug withdrawal syndrome
  • pain
  • fatigue
40-49:
  • pain
  • depression
  • anxiety
  • back pain
  • headache
  • fatigue
  • nausea
  • arthralgia
  • chest pain
  • muscle spasms
50-59:
  • pain
  • nausea
  • depression
  • arthralgia
  • anxiety
  • fatigue
  • fall
  • insomnia
  • back pain
  • diarrhoea
60+:
  • pain
  • fall
  • dyspnoea
  • fatigue
  • nausea
  • back pain
  • anxiety
  • pain in extremity
  • dizziness
  • anaemia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Tramadol hydrochloride (tramadol hydrochloride) is often used to treat pain. Gabapentin (gabapentin) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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