Review: taking Tramadol hydrochloride and Gabapentin together


Summary

Drug interactions are reported among people who take Tramadol hydrochloride and Gabapentin together. This review analyzes the effectiveness and drug interactions between Tramadol hydrochloride and Gabapentin. It is created by eHealthMe based on reports of 10,931 people who take the same drugs from FDA and social media, and is updated regularly.

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Tramadol Hydrochloride

Tramadol hydrochloride has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol hydrochloride 9,979 users)

Gabapentin

Gabapentin has active ingredients of gabapentin. It is often used in pain. (latest outcomes from Gabapentin 83,499 users)

On Sep, 18, 2016

10,931 people who take Tramadol Hydrochloride, Gabapentin are studied.


Number of reports submitted per year:

Tramadol hydrochloride and Gabapentin drug interactions.

Drug effectiveness over time:

Tramadol Hydrochloride:
  • < 1 month: 9.0% - (2 of 22 people)
  • 1 - 6 months: 15.0% - (9 of 60 people)
  • 6 - 12 months: 21.0% - (10 of 47 people)
  • 1 - 2 years: 22.0% - (18 of 80 people)
  • 2 - 5 years: 27.0% - (17 of 61 people)
  • 5 - 10 years: 29.0% - (10 of 34 people)
  • 10+ years: 60.0% - (6 of 10 people)
  • not specified: 20.0% - (1 of 5 people)
Gabapentin:
  • < 1 month: 20.0% - (6 of 30 people)
  • 1 - 6 months: 15.0% - (12 of 79 people)
  • 6 - 12 months: 18.0% - (9 of 50 people)
  • 1 - 2 years: 25.0% - (14 of 54 people)
  • 2 - 5 years: 25.0% - (20 of 77 people)
  • 5 - 10 years: 50.0% - (12 of 24 people)
  • 10+ years: 50.0% - (5 of 10 people)
  • not specified: 25.0% - (1 of 4 people)

Drug effectiveness by gender:

Tramadol Hydrochloride:
  • female: 23.0% - (55 of 236 people)
  • male: 21.0% - (18 of 83 people)
Gabapentin:
  • female: 27.0% - (67 of 245 people)
  • male: 14.0% - (12 of 83 people)

Drug effectiveness by age:

Tramadol Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 33.0% - (1 of 3 people)
  • 20-29: 18.0% - (6 of 32 people)
  • 30-39: 18.0% - (10 of 54 people)
  • 40-49: 24.0% - (22 of 91 people)
  • 50-59: 19.0% - (15 of 78 people)
  • 60+: 31.0% - (19 of 61 people)
Gabapentin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 66.0% - (2 of 3 people)
  • 20-29: 18.0% - (6 of 32 people)
  • 30-39: 25.0% - (14 of 56 people)
  • 40-49: 29.0% - (28 of 95 people)
  • 50-59: 22.0% - (18 of 80 people)
  • 60+: 17.0% - (11 of 62 people)

Most common drug interactions over time *:

< 1 month:
  • confusional state
  • hallucination
  • anxiety
  • gait disturbance
  • insomnia
  • memory impairment
  • depression
  • nightmare
  • abdominal pain upper
  • coordination abnormal
1 - 6 months:
  • pain
  • confusional state
  • nausea
  • drug ineffective
  • depression
  • dizziness
  • arthralgia
  • fatigue
  • disorientation
  • fall
6 - 12 months:
  • depression
  • dizziness
  • loss of consciousness
  • dehydration
  • drug ineffective
  • nausea
  • insomnia
  • paraesthesia
  • disorientation
  • hostility
1 - 2 years:
  • dizziness
  • pain
  • depression
  • drug ineffective
  • chest pain
  • muscle weakness
  • malaise
  • fatigue
  • anxiety
  • leg pain
2 - 5 years:
  • anxiety
  • depression
  • fatigue
  • dizziness
  • suicide attempt
  • chronic pain
  • neuropathy
  • aggression
  • chest pain
  • drug ineffective
5 - 10 years:
  • convulsion
  • accidental overdose
  • drug withdrawal syndrome
  • loss of consciousness
  • feeling of body temperature change
  • hypoaesthesia
  • retching
  • cerebrovascular accident
  • swelling
  • inflammatory pain
10+ years:
  • headache
  • insomnia
  • anger
  • anxiety
  • depression
  • drug ineffective
  • dry hair
  • hair thinning
  • irritability
  • restless leg syndrome
not specified:
  • pain
  • nausea
  • drug ineffective
  • fatigue
  • anxiety
  • fall
  • headache
  • dyspnoea
  • depression
  • dizziness

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • fatigue
  • drug ineffective
  • headache
  • anxiety
  • fall
  • dyspnoea
  • pain in extremity
  • diarrhoea
male:
  • pain
  • depression
  • drug ineffective
  • fatigue
  • anxiety
  • dizziness
  • fall
  • dyspnoea
  • back pain
  • nausea

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • premature baby
  • type 2 diabetes mellitus
  • abdominal distension
  • abdominal pain upper
  • asthenia
  • blood cholesterol increased
  • blood triglycerides increased
  • chest pain
  • decreased appetite
2-9:
  • infection
  • chills
  • convulsion
  • diarrhoea
  • febrile neutropenia
  • hypertonia
  • hypoventilation
  • mucosal inflammation
  • mydriasis
  • overdose
10-19:
  • confusional state
  • rash
  • flushing
  • hallucination, visual
  • suicidal ideation
  • tremor
  • headache
  • vomiting
  • emotional distress
  • convulsion
20-29:
  • pain
  • dizziness
  • depression
  • insomnia
  • fatigue
  • injury
  • headache
  • anxiety
  • dyspnoea
  • drug ineffective
30-39:
  • depression
  • headache
  • dizziness
  • completed suicide
  • anxiety
  • drug ineffective
  • nausea
  • pain
  • fatigue
  • dyspnoea
40-49:
  • pain
  • depression
  • anxiety
  • headache
  • nausea
  • back pain
  • fatigue
  • arthralgia
  • drug ineffective
  • dizziness
50-59:
  • pain
  • nausea
  • drug ineffective
  • fatigue
  • diarrhoea
  • depression
  • arthralgia
  • fall
  • headache
  • anxiety
60+:
  • pain
  • fall
  • dyspnoea
  • fatigue
  • nausea
  • pain in extremity
  • anxiety
  • diarrhoea
  • back pain
  • asthenia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Tramadol hydrochloride (tramadol hydrochloride) is often used to treat pain. Gabapentin (gabapentin) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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