Review: taking Tramadol hydrochloride and Gabapentin together


Summary

Drug interactions are reported among people who take Tramadol hydrochloride and Gabapentin together. This review analyzes the effectiveness and drug interactions between Tramadol hydrochloride and Gabapentin. It is created by eHealthMe based on reports of 5,535 people who take the same drugs from FDA and social media, and is updated regularly.

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Tramadol Hydrochloride

Tramadol hydrochloride has active ingredients of tramadol. It is often used in pain. (latest outcomes from Tramadol hydrochloride 7,245 users)

Gabapentin

Gabapentin has active ingredients of gabapentin. It is often used in pain. (latest outcomes from Gabapentin 38,775 users)

On Jul, 20, 2016

5,535 people who take Tramadol Hydrochloride, Gabapentin are studied.


Number of reports submitted per year:

Tramadol hydrochloride and Gabapentin drug interactions.

Drug effectiveness over time:

Tramadol Hydrochloride:
  • < 1 month: 8.0% - (2 of 24 people)
  • 1 - 6 months: 13.0% - (12 of 87 people)
  • 6 - 12 months: 27.0% - (19 of 69 people)
  • 1 - 2 years: 23.0% - (23 of 96 people)
  • 2 - 5 years: 22.0% - (21 of 95 people)
  • 5 - 10 years: 22.0% - (14 of 61 people)
  • 10+ years: 58.0% - (17 of 29 people)
  • not specified: 20.0% - (1 of 5 people)
Gabapentin:
  • < 1 month: 17.0% - (8 of 45 people)
  • 1 - 6 months: 13.0% - (13 of 100 people)
  • 6 - 12 months: 14.0% - (9 of 61 people)
  • 1 - 2 years: 17.0% - (14 of 81 people)
  • 2 - 5 years: 24.0% - (28 of 116 people)
  • 5 - 10 years: 36.0% - (13 of 36 people)
  • 10+ years: 22.0% - (5 of 22 people)
  • not specified: 20.0% - (1 of 5 people)

Drug effectiveness by gender:

Tramadol Hydrochloride:
  • female: 22.0% - (84 of 366 people)
  • male: 25.0% - (25 of 100 people)
Gabapentin:
  • female: 21.0% - (79 of 365 people)
  • male: 11.0% - (12 of 101 people)

Drug effectiveness by age:

Tramadol Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 33.0% - (1 of 3 people)
  • 20-29: 22.0% - (10 of 44 people)
  • 30-39: 17.0% - (13 of 73 people)
  • 40-49: 17.0% - (28 of 156 people)
  • 50-59: 27.0% - (32 of 117 people)
  • 60+: 34.0% - (25 of 73 people)
Gabapentin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 66.0% - (2 of 3 people)
  • 20-29: 13.0% - (6 of 44 people)
  • 30-39: 18.0% - (14 of 76 people)
  • 40-49: 22.0% - (34 of 148 people)
  • 50-59: 19.0% - (23 of 121 people)
  • 60+: 16.0% - (12 of 74 people)

Most common drug interactions over time *:

< 1 month:
  • confusional state
  • somnolence
  • peripheral motor neuropathy
  • hallucination
  • drug ineffective
  • nausea
  • dizziness
  • headache
  • malaise
  • tremor
1 - 6 months:
  • depression
  • pain
  • fatigue
  • confusional state
  • disorientation
  • dizziness
  • nausea
  • vasculitic rash
  • drug ineffective
  • feeling hot
6 - 12 months:
  • depression
  • dizziness
  • dehydration
  • insomnia
  • nausea
  • disorientation
  • loss of consciousness
  • mental status changes
  • muscle twitching
  • bone pain
1 - 2 years:
  • dizziness
  • depression
  • muscle weakness
  • chest pain
  • pain
  • fatigue
  • leg pain
  • menstruation irregular
  • anxiety
  • malaise
2 - 5 years:
  • anxiety
  • depression
  • fatigue
  • suicide attempt
  • chronic pain
  • neuropathy
  • chest pain
  • dizziness
  • drug ineffective
  • suicidal ideation
5 - 10 years:
  • convulsion
  • accidental overdose
  • drug withdrawal syndrome
  • loss of consciousness
  • feeling of body temperature change
  • retching
  • cerebrovascular accident
  • hypoaesthesia
  • inflammatory pain
  • swelling
10+ years:
  • headache
  • insomnia
  • anger
  • anxiety
  • depression
  • dry hair
  • hair thinning
  • irritability
  • restless leg syndrome
  • short-term memory loss
not specified:
  • pain
  • anxiety
  • nausea
  • depression
  • fatigue
  • dyspnoea
  • back pain
  • fall
  • headache
  • arthralgia

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • anxiety
  • fatigue
  • dyspnoea
  • depression
  • fall
  • headache
  • back pain
  • pain in extremity
male:
  • pain
  • depression
  • anxiety
  • dizziness
  • nausea
  • dyspnoea
  • drug ineffective
  • fatigue
  • back pain
  • chest pain

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • premature baby
  • type 2 diabetes mellitus
  • blood cholesterol increased
  • blood triglycerides increased
  • chest pain
  • diabetes mellitus
  • encephalopathy
  • haematoma
  • hyperammonaemia
2-9:
  • arthritis bacterial
  • cardio-respiratory arrest
  • chest pain
  • dyspnoea
  • feeling abnormal
  • influenza like illness
  • insomnia
  • joint swelling
  • myositis
  • sweat gland disorder
10-19:
  • confusional state
  • flushing
  • rash
  • hallucination, visual
  • headache
  • suicidal ideation
  • tremor
  • emotional distress
  • vomiting
  • febrile bone marrow aplasia
20-29:
  • insomnia
  • abdominal distension
  • dizziness
  • depression
  • fatigue
  • mania
  • somnolence
  • pain
  • alopecia
  • balance disorder
30-39:
  • depression
  • anxiety
  • headache
  • drug ineffective
  • dizziness
  • dyspnoea
  • nausea
  • drug withdrawal syndrome
  • drug dependence
  • pain
40-49:
  • pain
  • depression
  • anxiety
  • back pain
  • headache
  • arthralgia
  • fatigue
  • nausea
  • muscle spasms
  • chest pain
50-59:
  • nausea
  • pain
  • anxiety
  • depression
  • insomnia
  • fatigue
  • arthralgia
  • hypoaesthesia
  • diarrhoea
  • back pain
60+:
  • fall
  • pain
  • dyspnoea
  • fatigue
  • nausea
  • anxiety
  • back pain
  • anaemia
  • pain in extremity
  • asthenia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Tramadol hydrochloride (tramadol) is often used to treat pain. Gabapentin (gabapentin) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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