Review: taking Tramadol hydrochloride and Ibuprofen together


Summary

Drug interactions are reported among people who take Tramadol hydrochloride and Ibuprofen together. This review analyzes the effectiveness and drug interactions between Tramadol hydrochloride and Ibuprofen. It is created by eHealthMe based on reports of 5,970 people who take the same drugs from FDA and social media, and is updated regularly.

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Tramadol Hydrochloride

Tramadol hydrochloride has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol hydrochloride 9,980 users)

Ibuprofen

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from Ibuprofen 92,739 users)

On Sep, 16, 2016

5,970 people who take Tramadol Hydrochloride, Ibuprofen are studied.


Number of reports submitted per year:

Tramadol hydrochloride and Ibuprofen drug interactions.

Drug effectiveness over time:

Tramadol Hydrochloride:
  • < 1 month: 40.0% - (10 of 25 people)
  • 1 - 6 months: 12.0% - (2 of 16 people)
  • 6 - 12 months: 26.0% - (6 of 23 people)
  • 1 - 2 years: 23.0% - (6 of 26 people)
  • 2 - 5 years: 35.0% - (6 of 17 people)
  • 5 - 10 years: 46.0% - (6 of 13 people)
  • 10+ years: 0.0% - (0 of 3 people)
  • not specified: 50.0% - (2 of 4 people)
Ibuprofen:
  • < 1 month: 42.0% - (8 of 19 people)
  • 1 - 6 months: 22.0% - (4 of 18 people)
  • 6 - 12 months: 18.0% - (2 of 11 people)
  • 1 - 2 years: 18.0% - (2 of 11 people)
  • 2 - 5 years: 13.0% - (3 of 23 people)
  • 5 - 10 years: 45.0% - (9 of 20 people)
  • 10+ years: 38.0% - (8 of 21 people)
  • not specified: 25.0% - (1 of 4 people)

Drug effectiveness by gender:

Tramadol Hydrochloride:
  • female: 30.0% - (27 of 90 people)
  • male: 29.0% - (11 of 37 people)
Ibuprofen:
  • female: 33.0% - (30 of 90 people)
  • male: 18.0% - (7 of 37 people)

Drug effectiveness by age:

Tramadol Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 23.0% - (4 of 17 people)
  • 30-39: 39.0% - (9 of 23 people)
  • 40-49: 38.0% - (17 of 44 people)
  • 50-59: 15.0% - (5 of 32 people)
  • 60+: 30.0% - (3 of 10 people)
Ibuprofen:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 35.0% - (6 of 17 people)
  • 30-39: 25.0% - (6 of 24 people)
  • 40-49: 31.0% - (14 of 44 people)
  • 50-59: 25.0% - (8 of 31 people)
  • 60+: 30.0% - (3 of 10 people)

Most common drug interactions over time *:

< 1 month:
  • vomiting
  • nausea
  • pain
  • melaena
  • diarrhoea
  • asthenia
  • dyspnoea
  • headache
  • malaise
  • renal failure acute
1 - 6 months:
  • hyperuricaemia
  • blood uric acid increased
  • dyspepsia
  • asthenia
  • diarrhoea
  • haemorrhoids
  • nausea
  • agranulocytosis
  • dyspnoea
  • rectal haemorrhage
6 - 12 months:
  • nausea
  • mental status changes
  • drug intolerance
  • hot flush
  • lymphoedema
  • constipation
  • depression
  • disorientation
  • dizziness
  • epilepsy
1 - 2 years:
  • pain
  • deep vein thrombosis
  • haemorrhage
  • international normalised ratio increased
  • fatigue
  • gastrointestinal haemorrhage
  • haematemesis
  • depression
  • retroperitoneal haematoma
  • anxiety aggravated
2 - 5 years:
  • depression
  • pain
  • anaemia
  • deep vein thrombosis
  • anxiety
  • oedema peripheral
  • pain in extremity
  • pancytopenia
  • renal impairment
  • feeling hot
5 - 10 years:
  • depression
  • anaemia
  • anxiety
  • constipation
  • fatigue
  • gastrooesophageal reflux disease
  • pancytopenia
  • renal impairment
  • abdominal distension
  • dyspepsia
10+ years:
  • liver disorder
  • fatigue
  • muscle twitching
  • nausea
  • anxiety
  • apraxia
  • confusion
  • depression
  • headache
  • memory impairment
not specified:
  • pain
  • nausea
  • fatigue
  • anxiety
  • headache
  • drug ineffective
  • dyspnoea
  • back pain
  • depression
  • vomiting

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • anxiety
  • fatigue
  • headache
  • drug ineffective
  • depression
  • injury
  • vomiting
  • pain in extremity
male:
  • nausea
  • pain
  • dyspnoea
  • depression
  • fatigue
  • asthenia
  • back pain
  • anxiety
  • vomiting
  • drug ineffective

Most common drug interactions by age *:

0-1:
  • atrial septal defect
  • macrocephaly
  • neonatal respiratory distress syndrome
  • pulmonary artery stenosis congenital
  • foetal exposure during pregnancy
  • maternal drugs affecting foetus
  • adjustment disorder
  • apgar score low
  • bradycardia neonatal
  • cyanosis neonatal
2-9:
  • abdominal pain
  • actinic keratosis
  • anaemia
  • appendicitis
  • bone disorder
  • cardiac failure congestive
  • cardiac murmur
  • cardiomyopathy
  • carpal tunnel syndrome
  • cerebral calcification
10-19:
  • pain
  • anxiety
  • cholecystitis chronic
  • completed suicide
  • headache
  • injury
  • vomiting
  • abdominal pain
  • gallbladder disorder
  • nausea
20-29:
  • pain
  • injury
  • deep vein thrombosis
  • anxiety
  • pulmonary embolism
  • nausea
  • cholelithiasis
  • cholecystitis chronic
  • depression
  • gallbladder disorder
30-39:
  • pain
  • anxiety
  • depression
  • pulmonary embolism
  • nausea
  • injury
  • deep vein thrombosis
  • headache
  • pain in extremity
  • chest pain
40-49:
  • pain
  • nausea
  • headache
  • anxiety
  • back pain
  • depression
  • dyspnoea
  • fatigue
  • arthralgia
  • injury
50-59:
  • nausea
  • pain
  • anxiety
  • diarrhoea
  • fatigue
  • depression
  • back pain
  • insomnia
  • fall
  • cough
60+:
  • fatigue
  • nausea
  • dyspnoea
  • pain
  • asthenia
  • drug ineffective
  • back pain
  • diarrhoea
  • vomiting
  • dizziness

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Tramadol hydrochloride (tramadol hydrochloride) is often used to treat pain. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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