Review: taking Tramadol hydrochloride and Wellbutrin together


Summary

Drug interactions are reported among people who take Tramadol hydrochloride and Wellbutrin together. This review analyzes the effectiveness and drug interactions between Tramadol hydrochloride and Wellbutrin. It is created by eHealthMe based on reports of 2,734 people who take the same drugs from FDA and social media, and is updated regularly.

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Tramadol Hydrochloride

Tramadol hydrochloride has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol hydrochloride 9,979 users)

Wellbutrin

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from Wellbutrin 69,048 users)

On Sep, 17, 2016

2,734 people who take Tramadol Hydrochloride, Wellbutrin are studied.


Number of reports submitted per year:

Tramadol hydrochloride and Wellbutrin drug interactions.

Drug effectiveness over time:

Tramadol Hydrochloride:
  • < 1 month: 24.0% - (6 of 25 people)
  • 1 - 6 months: 14.0% - (5 of 34 people)
  • 6 - 12 months: 23.0% - (4 of 17 people)
  • 1 - 2 years: 31.0% - (11 of 35 people)
  • 2 - 5 years: 38.0% - (8 of 21 people)
  • 5 - 10 years: 42.0% - (8 of 19 people)
  • 10+ years: 16.0% - (1 of 6 people)
  • not specified: 0.0% - (0 of 0 people)
Wellbutrin:
  • < 1 month: 27.0% - (3 of 11 people)
  • 1 - 6 months: 25.0% - (7 of 28 people)
  • 6 - 12 months: 26.0% - (6 of 23 people)
  • 1 - 2 years: 29.0% - (8 of 27 people)
  • 2 - 5 years: 36.0% - (14 of 38 people)
  • 5 - 10 years: 50.0% - (11 of 22 people)
  • 10+ years: 37.0% - (6 of 16 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Tramadol Hydrochloride:
  • female: 28.0% - (36 of 125 people)
  • male: 21.0% - (7 of 32 people)
Wellbutrin:
  • female: 31.0% - (41 of 131 people)
  • male: 42.0% - (15 of 35 people)

Drug effectiveness by age:

Tramadol Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 50.0% - (1 of 2 people)
  • 20-29: 33.0% - (4 of 12 people)
  • 30-39: 31.0% - (13 of 41 people)
  • 40-49: 27.0% - (13 of 47 people)
  • 50-59: 14.0% - (5 of 34 people)
  • 60+: 33.0% - (7 of 21 people)
Wellbutrin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 36.0% - (4 of 11 people)
  • 30-39: 34.0% - (15 of 43 people)
  • 40-49: 29.0% - (16 of 54 people)
  • 50-59: 39.0% - (13 of 33 people)
  • 60+: 29.0% - (7 of 24 people)

Most common drug interactions over time *:

< 1 month:
  • nausea
  • cardiac arrest
  • feeling abnormal
  • headache
  • anxiety
  • grand mal convulsion
  • fall
  • convulsion
  • dysarthria
  • feeling jittery
1 - 6 months:
  • pain
  • anxiety
  • cholecystitis chronic
  • emotional distress
  • grand mal convulsion
  • injury
  • nausea
  • abdominal pain
  • alanine aminotransferase increased
  • convulsion
6 - 12 months:
  • convulsion
  • nausea
  • abdominal pain upper
  • asthenia
  • cholecystitis
  • cholelithiasis
  • pancreatitis
  • pyrexia
  • vomiting
  • drug withdrawal syndrome
1 - 2 years:
  • convulsion
  • fatigue
  • deep vein thrombosis
  • insomnia
  • short-term memory loss
  • sleep disorder
  • diarrhoea
  • high blood cholesterol
  • low thyroid
  • muscle weakness
2 - 5 years:
  • anxiety
  • pain
  • abdominal pain
  • cardiac disorder
  • cerebrovascular accident
  • chest pain
  • myocardial infarction
  • abdominal pain upper
  • arthritis
  • back injury
5 - 10 years:
  • depression
  • suicidal ideation
  • anxiety
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • paranoia
  • weight gain
  • convulsion
  • loss of consciousness
  • suicide attempt
  • abnormal behaviour
10+ years:
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • abdominal pain
  • dizziness
  • dry mouth
  • heart pounding
  • heart racing
  • insomnia
  • migraine without aura
  • po2 increased
  • weight gain poor
not specified:
  • pain
  • anxiety
  • nausea
  • fall
  • fatigue
  • dyspnoea
  • depression
  • headache
  • back pain
  • diarrhoea

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • anxiety
  • fall
  • fatigue
  • diarrhoea
  • headache
  • dyspnoea
  • constipation
  • cough
male:
  • anxiety
  • pain
  • fatigue
  • depression
  • back pain
  • fall
  • nausea
  • insomnia
  • dyspnoea
  • headache

Most common drug interactions by age *:

0-1:
  • diabetes mellitus
2-9:
  • accidental exposure
  • blood pressure decreased
  • hallucination, auditory
  • heart rate increased
  • rhinorrhoea
  • upper respiratory tract infection
  • white blood cell count decreased
10-19:
  • nausea
  • vomiting
  • abdominal pain
  • cholecystitis chronic
  • completed suicide
  • arthropathy
  • cardiac arrest
  • cardio-respiratory arrest
  • deafness
  • fatigue
20-29:
  • nausea
  • anxiety
  • cholelithiasis
  • depression
  • abdominal pain upper
  • headache
  • pain
  • cardiac arrest
  • drug ineffective
  • gallbladder disorder
30-39:
  • diabetes mellitus
  • anxiety
  • nausea
  • dizziness
  • neuropathy peripheral
  • deep vein thrombosis
  • pain
  • back pain
  • convulsion
  • hypertension
40-49:
  • pain
  • fall
  • anxiety
  • nausea
  • back pain
  • dyspnoea
  • constipation
  • fatigue
  • depression
  • arthralgia
50-59:
  • pain
  • fall
  • nausea
  • anxiety
  • diarrhoea
  • fatigue
  • pyrexia
  • cough
  • emotional distress
  • anaemia
60+:
  • fatigue
  • fall
  • anxiety
  • diarrhoea
  • pain
  • nausea
  • serotonin syndrome
  • completed suicide
  • depression
  • hypertension

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Tramadol hydrochloride (tramadol hydrochloride) is often used to treat pain. Wellbutrin (bupropion hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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