Review: taking Tramadol and Adderall together


Summary

Drug interactions are reported among people who take Tramadol and Adderall together. This review analyzes the effectiveness and drug interactions between Tramadol and Adderall. It is created by eHealthMe based on reports of 424 people who take the same drugs from FDA and social media, and is updated regularly.

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Tramadol

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol 49,036 users)

Adderall

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. (latest outcomes from Adderall 18,354 users)

On Aug, 21, 2016

424 people who take Tramadol, Adderall are studied.


Number of reports submitted per year:

Tramadol and Adderall drug interactions.

Drug effectiveness over time:

Tramadol:
  • < 1 month: 9.0% - (2 of 21 people)
  • 1 - 6 months: 31.0% - (6 of 19 people)
  • 6 - 12 months: 11.0% - (2 of 17 people)
  • 1 - 2 years: 35.0% - (7 of 20 people)
  • 2 - 5 years: 20.0% - (3 of 15 people)
  • 5 - 10 years: 38.0% - (5 of 13 people)
  • 10+ years: 0.0% - (0 of 2 people)
  • not specified: 100.0% - (1 of 1 people)
Adderall:
  • < 1 month: 33.0% - (5 of 15 people)
  • 1 - 6 months: 47.0% - (9 of 19 people)
  • 6 - 12 months: 46.0% - (7 of 15 people)
  • 1 - 2 years: 65.0% - (15 of 23 people)
  • 2 - 5 years: 56.0% - (13 of 23 people)
  • 5 - 10 years: 75.0% - (3 of 4 people)
  • 10+ years: 80.0% - (4 of 5 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Tramadol:
  • female: 24.0% - (20 of 83 people)
  • male: 24.0% - (6 of 25 people)
Adderall:
  • female: 59.0% - (48 of 81 people)
  • male: 37.0% - (9 of 24 people)

Drug effectiveness by age:

Tramadol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 31.0% - (9 of 29 people)
  • 30-39: 28.0% - (12 of 42 people)
  • 40-49: 14.0% - (3 of 21 people)
  • 50-59: 15.0% - (2 of 13 people)
  • 60+: 0.0% - (0 of 2 people)
Adderall:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 41.0% - (12 of 29 people)
  • 30-39: 62.0% - (25 of 40 people)
  • 40-49: 52.0% - (11 of 21 people)
  • 50-59: 69.0% - (9 of 13 people)
  • 60+: 0.0% - (0 of 1 people)

Most common drug interactions over time *:

< 1 month:
  • breathing difficulty
  • rash erythematous aggravated
  • dizziness
  • mental status changes
  • nausea and vomiting
  • abnormal behaviour
  • application site pruritus
  • blood potassium decreased
  • blood thyroid stimulating hormone decreased
  • carpal tunnel syndrome
1 - 6 months:
  • cluster headache
  • eye pain
  • pain in jaw
  • swallowing difficulty
  • acne
  • anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension
  • apathy
  • chest pain
  • deep vein thrombosis
  • erectile dysfunction
6 - 12 months:
  • cognitive deterioration
  • memory impairment
  • fatigue
  • agitation
  • dizziness
  • dyspnoea
  • hot flashes
  • migraine
  • nausea
  • nerve damage - diabetic
1 - 2 years:
  • obesity
  • depression
  • injury
  • insomnia
  • lung consolidation
  • nausea and vomiting
  • pulmonary embolism
  • chest pain
  • constipation
  • cytogenetic analysis abnormal
2 - 5 years:
  • pain
  • depression
  • nausea
  • breathing difficulty
  • chest pain
  • cognitive deterioration
  • deep vein thrombosis
  • dyspnoea
  • memory impairment
  • pain in extremity
5 - 10 years:
  • bile duct stone
  • cholecystitis chronic
  • deformity
  • disability
  • dizziness
  • nerve damage - diabetic
  • neuropathy - sciatic nerve
  • pain - back
  • peripheral neuropathy
  • anxiety
10+ years:
  • dizziness
  • euphoric mood
  • high blood pressure
  • muscle fatigue
  • sweating - excessive
not specified:
  • fatigue
  • pain
  • headache
  • nausea
  • anxiety
  • dyspnoea
  • arthralgia
  • dyspepsia
  • pain in extremity
  • back pain

Most common drug interactions by gender *:

female:
  • pain
  • fatigue
  • headache
  • anxiety
  • nausea
  • pulmonary embolism
  • dyspnoea
  • hypoaesthesia
  • pain in extremity
  • deep vein thrombosis
male:
  • fatigue
  • nausea
  • rheumatoid arthritis
  • arthralgia
  • chest discomfort
  • headache
  • completed suicide
  • dyspnoea
  • depression
  • pain

Most common drug interactions by age *:

10-19:
  • cholecystitis chronic
  • gallbladder disorder
  • pain
  • pancreatitis
  • sphincter of oddi dysfunction
  • fatigue
  • migraine
  • nausea
  • abdominal pain
  • abdominal pain upper
20-29:
  • nausea
  • gallbladder disorder
  • pain
  • injury
  • anxiety
  • pulmonary embolism
  • cholecystitis chronic
  • abdominal discomfort
  • dyspnoea
  • emotional distress
30-39:
  • pain
  • pulmonary embolism
  • hypoaesthesia
  • pain in extremity
  • chest pain
  • bone marrow disorder
  • deep vein thrombosis
  • dyspnoea
  • fatigue
  • livedo reticularis
40-49:
  • headache
  • fatigue
  • dyspepsia
  • pain
  • anxiety
  • catatonia
  • nausea
  • blood potassium decreased
  • chest discomfort
  • dyspnoea
50-59:
  • fatigue
  • insomnia
  • nausea
  • hypoaesthesia
  • anxiety
  • back pain
  • hypertension
  • muscle spasms
  • paraesthesia
  • weight decreased
60+:
  • rheumatoid arthritis
  • depression
  • affect lability
  • fall
  • nausea
  • pain in extremity
  • anxiety
  • body mass index increased
  • memory impairment
  • mouth ulceration

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Tramadol (tramadol hydrochloride) is often used to treat pain. Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) is often used to treat attention deficit hyperactivity disorder. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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