Review: taking Tramadol and Ambien together


Summary

Drug interactions are reported among people who take Tramadol and Ambien together. This review analyzes the effectiveness and drug interactions between Tramadol and Ambien. It is created by eHealthMe based on reports of 3,251 people who take the same drugs from FDA and social media, and is updated regularly.

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Tramadol

Tramadol has active ingredients of tramadol. It is often used in pain. (latest outcomes from Tramadol 42,204 users)

Ambien

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. (latest outcomes from Ambien 46,184 users)

On Jul, 19, 2016

3,251 people who take Tramadol, Ambien are studied.


Number of reports submitted per year:

Tramadol and Ambien drug interactions.

Drug effectiveness over time:

Tramadol:
  • < 1 month: 11.0% - (2 of 18 people)
  • 1 - 6 months: 13.0% - (7 of 53 people)
  • 6 - 12 months: 16.0% - (4 of 25 people)
  • 1 - 2 years: 21.0% - (8 of 38 people)
  • 2 - 5 years: 39.0% - (18 of 46 people)
  • 5 - 10 years: 48.0% - (19 of 39 people)
  • 10+ years: 18.0% - (3 of 16 people)
  • not specified: 0.0% - (0 of 0 people)
Ambien:
  • < 1 month: 6.0% - (1 of 15 people)
  • 1 - 6 months: 46.0% - (18 of 39 people)
  • 6 - 12 months: 61.0% - (16 of 26 people)
  • 1 - 2 years: 63.0% - (21 of 33 people)
  • 2 - 5 years: 50.0% - (28 of 55 people)
  • 5 - 10 years: 70.0% - (31 of 44 people)
  • 10+ years: 65.0% - (13 of 20 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Tramadol:
  • female: 27.0% - (50 of 179 people)
  • male: 19.0% - (11 of 56 people)
Ambien:
  • female: 55.0% - (100 of 179 people)
  • male: 52.0% - (28 of 53 people)

Drug effectiveness by age:

Tramadol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 3 people)
  • 20-29: 9.0% - (2 of 21 people)
  • 30-39: 29.0% - (14 of 47 people)
  • 40-49: 12.0% - (6 of 48 people)
  • 50-59: 38.0% - (27 of 71 people)
  • 60+: 26.0% - (12 of 45 people)
Ambien:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 3 people)
  • 20-29: 66.0% - (14 of 21 people)
  • 30-39: 46.0% - (23 of 50 people)
  • 40-49: 54.0% - (26 of 48 people)
  • 50-59: 60.0% - (40 of 66 people)
  • 60+: 56.0% - (25 of 44 people)

Most common drug interactions over time *:

< 1 month:
  • diarrhoea
  • pneumonia
  • drug rash with eosinophilia and systemic symptoms
  • liver injury
  • neutropenia
  • rash
  • urinary tract infection
  • dermatitis exfoliative
  • gastric ulcer
  • varices oesophageal
1 - 6 months:
  • pain
  • abdominal pain
  • headache
  • depression
  • dizziness
  • insomnia
  • nausea
  • skin burning sensation
  • constipation
  • muscle tightness
6 - 12 months:
  • depression
  • dizziness
  • chest pain
  • dehydration
  • fatigue
  • lip dry
  • mitral valve incompetence
  • myocardial infarction
  • short-term memory loss
  • cognitive disorder
1 - 2 years:
  • dizziness
  • anxiety
  • injury
  • depression
  • mitral valve incompetence
  • myocardial infarction
  • asthenia
  • deep vein thrombosis
  • dry mouth
  • hepatic encephalopathy
2 - 5 years:
  • cognitive deterioration
  • basilar migraine
  • head injury
  • occipital neuralgia
  • memory impairment
  • depression
  • fatigue
  • urinary tract infection
  • abdominal pain
  • abdominal pain upper
5 - 10 years:
  • pain
  • anxiety
  • fatigue
  • cholecystitis
  • deep vein thrombosis
  • emotional distress
  • gallbladder disorder
  • libido decreased
  • neuropathy - sciatic nerve
  • pain - back
10+ years:
  • diazepam overdose
  • insomnia exacerbated
  • anxiety disorder
  • body dysmorphic disorder
  • body temperature fluctuation
  • borderline personality disorder
  • confusion
  • degenerative joint disease
  • drug-induced tremor
  • fatigue aggravated
not specified:
  • pain
  • nausea
  • anxiety
  • dyspnoea
  • fatigue
  • fall
  • back pain
  • arthralgia
  • diarrhoea
  • chest pain

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • anxiety
  • fatigue
  • back pain
  • fall
  • dyspnoea
  • arthralgia
  • diarrhoea
  • constipation
male:
  • dyspnoea
  • nausea
  • depression
  • chest pain
  • anxiety
  • fall
  • fatigue
  • pain
  • dizziness
  • pneumonia

Most common drug interactions by age *:

0-1:
  • blood cholesterol increased
  • blood triglycerides increased
  • cerebrovascular accident
  • diabetes mellitus
  • drug exposure during pregnancy
  • hyperprolactinaemia
  • leiomyoma
  • obesity
  • osteoarthritis
  • patellofemoral pain syndrome
10-19:
  • abdominal pain
  • nausea
  • vomiting
  • arthralgia
  • cholecystitis chronic
  • fatigue
  • headache
  • ill-defined disorder
  • systemic lupus erythematosus
  • allergen nos skin test positive
20-29:
  • torsade de pointes
  • cardiac arrest
  • pain
  • abdominal pain upper
  • loss of consciousness
  • nausea
  • ventricular fibrillation
  • vomiting
  • anxiety
  • coma
30-39:
  • arthralgia
  • nausea
  • pain
  • headache
  • drug dependence
  • depression
  • anxiety
  • drug withdrawal syndrome
  • hypertension
  • pyrexia
40-49:
  • nausea
  • back pain
  • fatigue
  • chest pain
  • pain
  • dyspnoea
  • depression
  • headache
  • fall
  • gastrooesophageal reflux disease
50-59:
  • nausea
  • pain
  • anxiety
  • oedema peripheral
  • fall
  • diarrhoea
  • arthralgia
  • depression
  • fatigue
  • anaemia
60+:
  • pain
  • dyspnoea
  • anxiety
  • fatigue
  • fall
  • back pain
  • diarrhoea
  • nausea
  • anaemia
  • asthenia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Tramadol (tramadol) is often used to treat pain. Ambien (zolpidem tartrate) is often used to treat insomnia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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