Review: taking Tramadol and Clonazepam together


Summary

Drug interactions are reported among people who take Tramadol and Clonazepam together. This review analyzes the effectiveness and drug interactions between Tramadol and Clonazepam. It is created by eHealthMe based on reports of 4,541 people who take the same drugs from FDA and social media, and is updated regularly.

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Tramadol

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol 73,714 users)

Clonazepam

Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from Clonazepam 60,448 users)

On Sep, 16, 2016

4,541 people who take Tramadol, Clonazepam are studied.


Number of reports submitted per year:

Tramadol and Clonazepam drug interactions.

Drug effectiveness over time:

Tramadol:
  • < 1 month: 44.0% - (11 of 25 people)
  • 1 - 6 months: 11.0% - (4 of 36 people)
  • 6 - 12 months: 19.0% - (4 of 21 people)
  • 1 - 2 years: 39.0% - (9 of 23 people)
  • 2 - 5 years: 35.0% - (12 of 34 people)
  • 5 - 10 years: 47.0% - (8 of 17 people)
  • 10+ years: 42.0% - (3 of 7 people)
  • not specified: 0.0% - (0 of 1 people)
Clonazepam:
  • < 1 month: 29.0% - (5 of 17 people)
  • 1 - 6 months: 44.0% - (11 of 25 people)
  • 6 - 12 months: 41.0% - (7 of 17 people)
  • 1 - 2 years: 68.0% - (11 of 16 people)
  • 2 - 5 years: 58.0% - (24 of 41 people)
  • 5 - 10 years: 60.0% - (17 of 28 people)
  • 10+ years: 52.0% - (9 of 17 people)
  • not specified: 0.0% - (0 of 2 people)

Drug effectiveness by gender:

Tramadol:
  • female: 30.0% - (35 of 116 people)
  • male: 33.0% - (16 of 48 people)
Clonazepam:
  • female: 52.0% - (62 of 118 people)
  • male: 48.0% - (22 of 45 people)

Drug effectiveness by age:

Tramadol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 2 people)
  • 20-29: 28.0% - (6 of 21 people)
  • 30-39: 35.0% - (12 of 34 people)
  • 40-49: 30.0% - (14 of 46 people)
  • 50-59: 36.0% - (13 of 36 people)
  • 60+: 24.0% - (6 of 25 people)
Clonazepam:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 2 people)
  • 20-29: 52.0% - (11 of 21 people)
  • 30-39: 48.0% - (18 of 37 people)
  • 40-49: 60.0% - (28 of 46 people)
  • 50-59: 55.0% - (19 of 34 people)
  • 60+: 34.0% - (8 of 23 people)

Most common drug interactions over time *:

< 1 month:
  • urinary tract infection
  • gastric ulcer
  • varices oesophageal
  • drug ineffective
  • back pain
  • confusional state
  • tremor
  • weight decreased
  • dyspnoea
  • nervousness
1 - 6 months:
  • anxiety
  • serotonin syndrome
  • cyanosis
  • dyspnoea
  • dizziness
  • drug withdrawal syndrome
  • headache
  • incontinence
  • pyrexia
  • suicidal ideation
6 - 12 months:
  • fatigue
  • disorientation
  • dizziness
  • hypotension
  • loss of consciousness
  • mental status changes
  • headache - mixed tension migraine
  • lightheadedness - dizzy
  • pneumonia
  • post-thoracotomy pain syndrome
1 - 2 years:
  • emotional distress
  • pain
  • anxiety
  • depression
  • headache
  • pathological gambling
  • suicidal ideation
  • cyanosis
  • peripheral ischaemia
  • short-term memory loss
2 - 5 years:
  • fatigue
  • anxiety
  • depression
  • headache
  • suicidal ideation
  • serotonin syndrome
  • sleep disorder
  • dizziness
  • arthralgia
  • muscle spasms
5 - 10 years:
  • anxiety
  • depression
  • pain
  • paranoia
  • cholecystitis
  • deep vein thrombosis
  • emotional distress
  • fatigue
  • gallbladder disorder
  • headache
10+ years:
  • insomnia
  • sinusitis
  • abdominal pain
  • addicted to drugs
  • affective disorder
  • ammonia increased
  • ankylosing spondylitis
  • atrial flutter
  • body temperature fluctuation
  • chest pain
not specified:
  • pain
  • depression
  • nausea
  • anxiety
  • headache
  • fatigue
  • arthralgia
  • fall
  • dizziness
  • dyspnoea

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • anxiety
  • depression
  • headache
  • arthralgia
  • fatigue
  • dyspnoea
  • dizziness
  • vomiting
male:
  • depression
  • pain
  • fall
  • drug ineffective
  • dizziness
  • anxiety
  • fatigue
  • headache
  • dyspnoea
  • drug abuse

Most common drug interactions by age *:

0-1:
  • drug withdrawal syndrome neonatal
  • feeding disorder neonatal
  • foetal exposure during pregnancy
  • hypoglycaemia
  • oxygen saturation decreased
  • respiratory rate increased
  • abdominal distension
  • abdominal pain upper
  • asthenia
  • blood chromogranin a increased
2-9:
  • death
  • dizziness
  • drug administration error
  • flushing
  • hallucination, visual
  • headache
  • panic disorder
10-19:
  • vomiting
  • febrile bone marrow aplasia
  • febrile neutropenia
  • mucosal inflammation
  • weight decreased
  • completed suicide
  • cholecystitis chronic
  • pain
  • nausea
  • cardiac arrest
20-29:
  • dyspnoea
  • headache
  • gait disturbance
  • depression
  • vomiting
  • serotonin syndrome
  • agitation
  • diarrhoea
  • urinary tract infection
  • overdose
30-39:
  • depression
  • headache
  • anxiety
  • dizziness
  • vomiting
  • dyspnoea
  • arthralgia
  • asthenia
  • fatigue
  • hyperhidrosis
40-49:
  • pain
  • nausea
  • headache
  • fatigue
  • depression
  • anxiety
  • arthralgia
  • dizziness
  • vomiting
  • insomnia
50-59:
  • pain
  • nausea
  • depression
  • fatigue
  • insomnia
  • fall
  • arthralgia
  • diarrhoea
  • drug ineffective
  • back pain
60+:
  • pain
  • fall
  • dyspnoea
  • anxiety
  • nausea
  • asthenia
  • dizziness
  • fatigue
  • pain in extremity
  • back pain

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Tramadol (tramadol hydrochloride) is often used to treat pain. Clonazepam (clonazepam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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