Review: taking Tramadol and Clonazepam together


Summary

Drug interactions are reported among people who take Tramadol and Clonazepam together. This review analyzes the effectiveness and drug interactions between Tramadol and Clonazepam. It is created by eHealthMe based on reports of 2,642 people who take the same drugs from FDA and social media, and is updated regularly.

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Tramadol

Tramadol has active ingredients of tramadol. It is often used in pain. (latest outcomes from Tramadol 42,204 users)

Clonazepam

Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from Clonazepam 39,941 users)

On Jul, 20, 2016

2,642 people who take Tramadol, Clonazepam are studied.


Number of reports submitted per year:

Tramadol and Clonazepam drug interactions.

Drug effectiveness over time:

Tramadol:
  • < 1 month: 56.0% - (18 of 32 people)
  • 1 - 6 months: 10.0% - (4 of 40 people)
  • 6 - 12 months: 12.0% - (4 of 31 people)
  • 1 - 2 years: 40.0% - (10 of 25 people)
  • 2 - 5 years: 37.0% - (14 of 37 people)
  • 5 - 10 years: 53.0% - (15 of 28 people)
  • 10+ years: 57.0% - (4 of 7 people)
  • not specified: 0.0% - (0 of 1 people)
Clonazepam:
  • < 1 month: 20.0% - (5 of 25 people)
  • 1 - 6 months: 46.0% - (13 of 28 people)
  • 6 - 12 months: 38.0% - (7 of 18 people)
  • 1 - 2 years: 76.0% - (16 of 21 people)
  • 2 - 5 years: 54.0% - (27 of 50 people)
  • 5 - 10 years: 60.0% - (21 of 35 people)
  • 10+ years: 50.0% - (8 of 16 people)
  • not specified: 0.0% - (0 of 4 people)

Drug effectiveness by gender:

Tramadol:
  • female: 32.0% - (46 of 142 people)
  • male: 38.0% - (23 of 59 people)
Clonazepam:
  • female: 47.0% - (68 of 142 people)
  • male: 52.0% - (29 of 55 people)

Drug effectiveness by age:

Tramadol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 2 people)
  • 20-29: 29.0% - (7 of 24 people)
  • 30-39: 38.0% - (15 of 39 people)
  • 40-49: 35.0% - (19 of 54 people)
  • 50-59: 35.0% - (17 of 48 people)
  • 60+: 32.0% - (11 of 34 people)
Clonazepam:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 2 people)
  • 20-29: 54.0% - (13 of 24 people)
  • 30-39: 41.0% - (18 of 43 people)
  • 40-49: 64.0% - (35 of 54 people)
  • 50-59: 44.0% - (19 of 43 people)
  • 60+: 38.0% - (12 of 31 people)

Most common drug interactions over time *:

< 1 month:
  • gastric ulcer
  • urinary tract infection
  • varices oesophageal
  • drug ineffective
  • tremor
  • confusional state
  • weight decreased
  • asthenia
  • back pain
  • febrile bone marrow aplasia
1 - 6 months:
  • anxiety
  • cyanosis
  • dizziness
  • pyrexia
  • serotonin syndrome
  • agitation
  • depression
  • restlessness
  • arthralgia
  • blood sodium decreased
6 - 12 months:
  • disorientation
  • dizziness
  • fatigue
  • hypotension
  • loss of consciousness
  • mental status changes
  • headache - mixed tension migraine
  • lightheadedness - dizzy
  • post-thoracotomy pain syndrome
  • pneumonia
1 - 2 years:
  • emotional distress
  • anxiety
  • depression
  • pain
  • short-term memory loss
  • cyanosis
  • hypersexuality
  • obsessive-compulsive personality disorder
  • pathological gambling
  • peripheral ischaemia
2 - 5 years:
  • fatigue
  • anxiety
  • depression
  • headache
  • sleep disorder
  • suicidal ideation
  • arthralgia
  • convulsion
  • dizziness
  • mood swings
5 - 10 years:
  • anxiety
  • depression
  • pain
  • paranoia
  • cholecystitis
  • deep vein thrombosis
  • emotional distress
  • fatigue
  • gallbladder disorder
  • headache
10+ years:
  • abdominal pain
  • addicted to drugs
  • affective disorder
  • ankylosing spondylitis
  • atrial flutter
  • chest pain
  • cholecystitis
  • cholelithiasis
  • chronic depression
  • chronic fatigue syndrome
not specified:
  • pain
  • depression
  • nausea
  • anxiety
  • headache
  • arthralgia
  • fatigue
  • dyspnoea
  • dizziness
  • fall

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • depression
  • nausea
  • arthralgia
  • headache
  • fatigue
  • vomiting
  • dyspnoea
  • dizziness
male:
  • depression
  • fall
  • pain
  • anxiety
  • dizziness
  • headache
  • drug ineffective
  • nausea
  • fatigue
  • dyspnoea

Most common drug interactions by age *:

0-1:
  • blood chromogranin a increased
  • diabetes mellitus
  • encephalopathy
  • hyperammonaemia
2-9:
  • death
  • hallucination, visual
  • panic disorder
10-19:
  • febrile bone marrow aplasia
  • febrile neutropenia
  • mucosal inflammation
  • weight decreased
  • vomiting
  • cholecystitis chronic
  • nausea
  • gallbladder disorder
  • pain
  • drug toxicity
20-29:
  • headache
  • overdose
  • depression
  • vomiting
  • anxiety
  • dyspnoea
  • abdominal pain
  • convulsion
  • diarrhoea
  • dizziness
30-39:
  • headache
  • depression
  • anxiety
  • dizziness
  • vomiting
  • dyspnoea
  • arthralgia
  • hyperhidrosis
  • asthenia
  • agitation
40-49:
  • pain
  • nausea
  • anxiety
  • headache
  • depression
  • fatigue
  • arthralgia
  • dizziness
  • insomnia
  • vomiting
50-59:
  • nausea
  • fatigue
  • insomnia
  • depression
  • arthralgia
  • diarrhoea
  • pain
  • back pain
  • anxiety
  • completed suicide
60+:
  • pain
  • fall
  • dyspnoea
  • anxiety
  • asthenia
  • back pain
  • confusional state
  • pain in extremity
  • nausea
  • chest pain

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Tramadol (tramadol) is often used to treat pain. Clonazepam (clonazepam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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