Tramadol and Ibuprofen drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Tramadol and Ibuprofen together. This review analyzes the effectiveness and drug interactions between Tramadol and Ibuprofen. It is created by eHealthMe based on reports of 6,082 people who take the same drugs from FDA, and is updated regularly.

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Tramadol

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol 77,309 users)

Ibuprofen

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from Ibuprofen 96,242 users)

On Feb, 26, 2017

6,082 people who take Tramadol, Ibuprofen are studied.


Number of reports submitted per year:

Tramadol and Ibuprofen drug interactions.

Most common drug interactions over time *:

< 1 month:
  • vomiting
  • nausea
  • pain
  • melaena
  • diarrhoea
  • hypotension
  • malaise
  • confusional state
  • headache
  • asthenia
1 - 6 months:
  • hyperuricaemia
  • blood uric acid increased
  • dyspepsia
  • asthenia
  • diarrhoea
  • haemorrhoids
  • agranulocytosis
  • dyspnoea
  • rectal haemorrhage
  • abdominal distension
6 - 12 months:
  • nausea
  • mental status changes
  • drug intolerance
  • hot flush
  • lymphoedema
  • dizziness
  • disorientation
  • epilepsy
  • hyperthermia
  • hypotension
1 - 2 years:
  • pain
  • deep vein thrombosis
  • haemorrhage
  • international normalised ratio increased
  • gastrointestinal haemorrhage
  • haematemesis
  • retroperitoneal haematoma
  • general physical health deterioration
  • pulmonary embolism
  • anaemia
2 - 5 years:
  • pain
  • anaemia
  • deep vein thrombosis
  • depression
  • anxiety
  • oedema peripheral
  • pain in extremity
  • pancytopenia
  • renal impairment
  • feeling hot
5 - 10 years:
  • depression
  • anaemia
  • anxiety
  • constipation
  • gastrooesophageal reflux disease
  • insomnia
  • pancytopenia
  • renal impairment
  • abdominal distension
  • drug ineffective
10+ years:
  • liver disorder
  • anxiety
  • blood pressure increased
  • depression
  • gastrointestinal haemorrhage
  • headache
  • malaise
  • neuropathy peripheral
  • pain
  • perineurial cyst
not specified:
  • pain
  • nausea
  • fatigue
  • anxiety
  • headache
  • drug ineffective
  • vomiting
  • dyspnoea
  • back pain
  • depression

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • anxiety
  • fatigue
  • headache
  • drug ineffective
  • vomiting
  • pain in extremity
  • injury
  • arthralgia
male:
  • nausea
  • pain
  • fatigue
  • depression
  • dyspnoea
  • back pain
  • vomiting
  • anxiety
  • asthenia
  • drug ineffective

Most common drug interactions by age *:

0-1:
  • atrial septal defect
  • macrocephaly
  • neonatal respiratory distress syndrome
  • pulmonary artery stenosis congenital
  • foetal exposure during pregnancy
  • maternal drugs affecting foetus
  • adjustment disorder
  • apgar score low
  • bradycardia neonatal
  • cyanosis neonatal
2-9:
  • abdominal pain
  • actinic keratosis
  • anaemia
  • appendicitis
  • bone disorder
  • cardiac failure congestive
  • cardiac murmur
  • cardiomyopathy
  • carpal tunnel syndrome
  • cerebral calcification
10-19:
  • pain
  • anxiety
  • cholecystitis chronic
  • completed suicide
  • headache
  • injury
  • vomiting
  • abdominal pain
  • gallbladder disorder
  • nausea
20-29:
  • pain
  • injury
  • deep vein thrombosis
  • anxiety
  • pulmonary embolism
  • nausea
  • cholelithiasis
  • cholecystitis chronic
  • depression
  • gallbladder disorder
30-39:
  • pain
  • anxiety
  • depression
  • pulmonary embolism
  • injury
  • nausea
  • deep vein thrombosis
  • headache
  • pain in extremity
  • chest pain
40-49:
  • pain
  • nausea
  • headache
  • anxiety
  • back pain
  • depression
  • dyspnoea
  • fatigue
  • arthralgia
  • vomiting
50-59:
  • nausea
  • pain
  • anxiety
  • diarrhoea
  • fatigue
  • back pain
  • insomnia
  • depression
  • fall
  • vomiting
60+:
  • fatigue
  • nausea
  • pain
  • dyspnoea
  • asthenia
  • drug ineffective
  • back pain
  • diarrhoea
  • vomiting
  • dizziness

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Tramadol and Ibuprofen?

Interactions between Tramadol and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Ibuprofen and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Tramadol (tramadol hydrochloride) is often used to treat pain. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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More questions for: Tramadol, Ibuprofen

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