Review: taking Tramadol and Ibuprofen together


Summary

Drug interactions are reported among people who take Tramadol and Ibuprofen together. This review analyzes the effectiveness and drug interactions between Tramadol and Ibuprofen. It is created by eHealthMe based on reports of 3,188 people who take the same drugs from FDA and social media, and is updated regularly.

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Tramadol

Tramadol has active ingredients of tramadol. It is often used in pain. (latest outcomes from Tramadol 42,204 users)

Ibuprofen

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from Ibuprofen 60,808 users)

On Jul, 20, 2016

3,188 people who take Tramadol, Ibuprofen are studied.


Number of reports submitted per year:

Tramadol and Ibuprofen drug interactions.

Drug effectiveness over time:

Tramadol:
  • < 1 month: 37.0% - (10 of 27 people)
  • 1 - 6 months: 12.0% - (2 of 16 people)
  • 6 - 12 months: 25.0% - (7 of 27 people)
  • 1 - 2 years: 20.0% - (6 of 29 people)
  • 2 - 5 years: 48.0% - (12 of 25 people)
  • 5 - 10 years: 50.0% - (8 of 16 people)
  • 10+ years: 0.0% - (0 of 4 people)
  • not specified: 50.0% - (2 of 4 people)
Ibuprofen:
  • < 1 month: 40.0% - (8 of 20 people)
  • 1 - 6 months: 23.0% - (5 of 21 people)
  • 6 - 12 months: 30.0% - (4 of 13 people)
  • 1 - 2 years: 18.0% - (2 of 11 people)
  • 2 - 5 years: 10.0% - (3 of 28 people)
  • 5 - 10 years: 39.0% - (9 of 23 people)
  • 10+ years: 38.0% - (10 of 26 people)
  • not specified: 25.0% - (1 of 4 people)

Drug effectiveness by gender:

Tramadol:
  • female: 32.0% - (34 of 106 people)
  • male: 30.0% - (13 of 42 people)
Ibuprofen:
  • female: 33.0% - (35 of 104 people)
  • male: 16.0% - (7 of 42 people)

Drug effectiveness by age:

Tramadol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 19.0% - (4 of 21 people)
  • 30-39: 42.0% - (14 of 33 people)
  • 40-49: 39.0% - (18 of 46 people)
  • 50-59: 19.0% - (7 of 36 people)
  • 60+: 36.0% - (4 of 11 people)
Ibuprofen:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 30.0% - (6 of 20 people)
  • 30-39: 18.0% - (6 of 33 people)
  • 40-49: 32.0% - (15 of 46 people)
  • 50-59: 31.0% - (11 of 35 people)
  • 60+: 36.0% - (4 of 11 people)

Most common drug interactions over time *:

< 1 month:
  • vomiting
  • melaena
  • nausea
  • pain
  • gastrointestinal haemorrhage
  • diarrhoea
  • peripheral ischaemia
  • pulmonary embolism
  • asthenia
  • death
1 - 6 months:
  • hyperuricaemia
  • blood uric acid increased
  • haemorrhoids
  • agranulocytosis
  • abdominal distension
  • constipation
  • dyspepsia
  • faeces hard
  • gastrooesophageal reflux disease
  • oedema
6 - 12 months:
  • constipation
  • disorientation
  • nausea
  • depression
  • dizziness
  • epilepsy
  • hyperthermia
  • hypotension
  • loss of consciousness
  • mental status changes
1 - 2 years:
  • pain
  • haemorrhage
  • deep vein thrombosis
  • international normalised ratio increased
  • fatigue
  • retroperitoneal haematoma
  • anxiety aggravated
  • depression
  • increased appetite
  • loss of hair
2 - 5 years:
  • depression
  • pain
  • deep vein thrombosis
  • anxiety
  • oedema peripheral
  • pain in extremity
  • feeling hot
  • hypertension
  • injury
  • limb injury
5 - 10 years:
  • depression
  • anxiety
  • constipation
  • gastrooesophageal reflux disease
  • abdominal distension
  • dyspepsia
  • liver disorder
  • nausea
  • suicidal ideation
  • confusion
10+ years:
  • liver disorder
  • fatigue
  • muscle twitching
  • nausea
  • apraxia
  • confusion
  • depression
  • memory impairment
  • mood swings
  • suicidal ideation
not specified:
  • pain
  • nausea
  • anxiety
  • fatigue
  • back pain
  • dyspnoea
  • depression
  • fall
  • vomiting
  • dizziness

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • anxiety
  • fatigue
  • depression
  • back pain
  • pain in extremity
  • injury
  • dyspnoea
  • headache
male:
  • anxiety
  • nausea
  • depression
  • pain
  • dyspnoea
  • back pain
  • fatigue
  • insomnia
  • asthenia
  • vomiting

Most common drug interactions by age *:

0-1:
  • diabetes mellitus
10-19:
  • pain
  • cholecystitis chronic
  • gallbladder disorder
  • abdominal pain
  • anxiety
  • injury
  • pulmonary embolism
  • deep vein thrombosis
  • cholelithiasis
  • headache
20-29:
  • pain
  • nausea
  • cholelithiasis
  • deep vein thrombosis
  • anxiety
  • gallbladder disorder
  • pulmonary embolism
  • cholecystitis chronic
  • injury
  • depression
30-39:
  • depression
  • pain
  • anxiety
  • nausea
  • chest pain
  • headache
  • pain in extremity
  • deep vein thrombosis
  • pulmonary embolism
  • fatigue
40-49:
  • pain
  • anxiety
  • nausea
  • back pain
  • headache
  • dyspnoea
  • depression
  • abdominal pain
  • anaemia
  • injury
50-59:
  • nausea
  • anxiety
  • pain
  • diarrhoea
  • insomnia
  • depression
  • back pain
  • oedema peripheral
  • cough
  • emotional distress
60+:
  • fatigue
  • nausea
  • dyspnoea
  • pain
  • anxiety
  • asthenia
  • back pain
  • vomiting
  • chest pain
  • fall

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Tramadol (tramadol) is often used to treat pain. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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