Review: taking Tramadol and Lorazepam together


Summary

Drug interactions are reported among people who take Tramadol and Lorazepam together. This review analyzes the effectiveness and drug interactions between Tramadol and Lorazepam. It is created by eHealthMe based on reports of 2,662 people who take the same drugs from FDA and social media, and is updated regularly.

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Tramadol

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol 42,204 users)

Lorazepam

Lorazepam has active ingredients of lorazepam. It is often used in stress and anxiety. (latest outcomes from Lorazepam 46,073 users)

On Jul, 24, 2016

2,662 people who take Tramadol, Lorazepam are studied.


Number of reports submitted per year:

Tramadol and Lorazepam drug interactions.

Drug effectiveness over time:

Tramadol:
  • < 1 month: 13.0% - (2 of 15 people)
  • 1 - 6 months: 22.0% - (5 of 22 people)
  • 6 - 12 months: 14.0% - (3 of 21 people)
  • 1 - 2 years: 36.0% - (9 of 25 people)
  • 2 - 5 years: 11.0% - (5 of 44 people)
  • 5 - 10 years: 53.0% - (8 of 15 people)
  • 10+ years: 35.0% - (5 of 14 people)
  • not specified: 20.0% - (1 of 5 people)
Lorazepam:
  • < 1 month: 0.0% - (0 of 12 people)
  • 1 - 6 months: 34.0% - (8 of 23 people)
  • 6 - 12 months: 28.0% - (6 of 21 people)
  • 1 - 2 years: 28.0% - (4 of 14 people)
  • 2 - 5 years: 36.0% - (18 of 49 people)
  • 5 - 10 years: 73.0% - (14 of 19 people)
  • 10+ years: 57.0% - (12 of 21 people)
  • not specified: 75.0% - (3 of 4 people)

Drug effectiveness by gender:

Tramadol:
  • female: 22.0% - (28 of 124 people)
  • male: 27.0% - (10 of 37 people)
Lorazepam:
  • female: 42.0% - (54 of 126 people)
  • male: 29.0% - (11 of 37 people)

Drug effectiveness by age:

Tramadol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 23.0% - (5 of 21 people)
  • 30-39: 30.0% - (8 of 26 people)
  • 40-49: 24.0% - (11 of 45 people)
  • 50-59: 17.0% - (6 of 35 people)
  • 60+: 23.0% - (8 of 34 people)
Lorazepam:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 52.0% - (11 of 21 people)
  • 30-39: 55.0% - (16 of 29 people)
  • 40-49: 43.0% - (18 of 41 people)
  • 50-59: 31.0% - (11 of 35 people)
  • 60+: 24.0% - (9 of 37 people)

Most common drug interactions over time *:

< 1 month:
  • urinary tract infection
  • gastric ulcer
  • varices oesophageal
  • sepsis
  • somnolence
  • diverticulitis
  • large intestine perforation
  • confusional state
  • vomiting
  • septic shock
1 - 6 months:
  • malaise
  • dizziness
  • vomiting
  • pyrexia
  • convulsion
  • depression
  • hyperhidrosis
  • serotonin syndrome
  • urinary retention
  • agitation
6 - 12 months:
  • dizziness
  • mental status changes
  • disorientation
  • hypotension
  • loss of consciousness
  • post-thoracotomy pain syndrome
  • depression
  • fatigue
  • insomnia
  • pneumonia
1 - 2 years:
  • bone and joint pain
  • insomnia
  • acromegaly
  • asthma
  • atrial fibrillation
  • back pain
  • cognitive deterioration
  • dry eyes
  • liver scan abnormal
  • mental status changes
2 - 5 years:
  • fatigue
  • anxiety
  • convulsion
  • muscle spasms
  • depression
  • dizziness
  • incontinence
  • agitation
  • arthralgia
  • blood sodium decreased
5 - 10 years:
  • tinnitus
  • loss of consciousness
  • nausea and vomiting
  • ammonia increased
  • anxiety
  • bladder infection
  • confusion
  • convulsion
  • discomfort
  • fatigue
10+ years:
  • headache
  • short-term memory loss
  • nausea
  • depression
  • insomnia exacerbated
  • neuropathy
  • anxiety disorder
  • body dysmorphic disorder
  • body temperature fluctuation
  • borderline personality disorder
not specified:
  • anxiety
  • nausea
  • pain
  • depression
  • asthenia
  • fatigue
  • arthralgia
  • dyspnoea
  • vomiting
  • diarrhoea

Most common drug interactions by gender *:

female:
  • anxiety
  • nausea
  • pain
  • fatigue
  • asthenia
  • dyspnoea
  • vomiting
  • depression
  • arthralgia
  • diarrhoea
male:
  • anxiety
  • nausea
  • depression
  • pain
  • insomnia
  • chest pain
  • asthenia
  • vomiting
  • fatigue
  • dyspnoea

Most common drug interactions by age *:

0-1:
  • type 2 diabetes mellitus
  • blood cholesterol increased
  • blood triglycerides increased
  • chest pain
  • congenital aortic anomaly
  • diabetes mellitus
  • dyspnoea
  • hyperprolactinaemia
  • interstitial lung disease
  • leiomyoma
2-9:
  • arterial thrombosis
  • blood pressure decreased
  • cardio-respiratory arrest
  • dyspnoea
  • general physical health deterioration
  • mesenteric artery embolism
  • renal failure acute
  • subileus
10-19:
  • headache
  • vomiting
  • abdominal pain
  • dehydration
  • drug withdrawal syndrome
  • anxiety
  • biliary dyskinesia
  • coeliac disease
  • cold sweat
  • constipation
20-29:
  • vomiting
  • nausea
  • injury
  • anxiety
  • convulsion
  • pain
  • tachycardia
  • deep vein thrombosis
  • derealisation
  • dyskinesia
30-39:
  • headache
  • arthralgia
  • depression
  • anxiety
  • vomiting
  • asthenia
  • suicidal ideation
  • dizziness
  • dyspnoea
  • hyperhidrosis
40-49:
  • pain
  • anxiety
  • nausea
  • depression
  • back pain
  • fatigue
  • pain in jaw
  • hypoaesthesia
  • vomiting
  • asthenia
50-59:
  • anxiety
  • nausea
  • bone disorder
  • pain
  • anaemia
  • pain in jaw
  • emotional distress
  • oedema peripheral
  • insomnia
  • diarrhoea
60+:
  • nausea
  • pain
  • fatigue
  • anxiety
  • dyspnoea
  • asthenia
  • back pain
  • weight decreased
  • fall
  • diarrhoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Tramadol (tramadol hydrochloride) is often used to treat pain. Lorazepam (lorazepam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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