Review: taking Tramadol and Omeprazole together


Summary

Drug interactions are reported among people who take Tramadol and Omeprazole together. This review analyzes the effectiveness and drug interactions between Tramadol and Omeprazole. It is created by eHealthMe based on reports of 11,181 people who take the same drugs from FDA and social media, and is updated regularly.

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Tramadol

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol 73,714 users)

Omeprazole

Omeprazole has active ingredients of omeprazole. It is often used in gastrooesophageal reflux disease. (latest outcomes from Omeprazole 154,416 users)

On Sep, 17, 2016

11,181 people who take Tramadol, Omeprazole are studied.


Number of reports submitted per year:

Tramadol and Omeprazole drug interactions.

Drug effectiveness over time:

Tramadol:
  • < 1 month: 18.0% - (3 of 16 people)
  • 1 - 6 months: 35.0% - (11 of 31 people)
  • 6 - 12 months: 20.0% - (6 of 29 people)
  • 1 - 2 years: 37.0% - (13 of 35 people)
  • 2 - 5 years: 30.0% - (7 of 23 people)
  • 5 - 10 years: 16.0% - (3 of 18 people)
  • 10+ years: 20.0% - (2 of 10 people)
  • not specified: 0.0% - (0 of 1 people)
Omeprazole:
  • < 1 month: 40.0% - (2 of 5 people)
  • 1 - 6 months: 31.0% - (7 of 22 people)
  • 6 - 12 months: 41.0% - (7 of 17 people)
  • 1 - 2 years: 65.0% - (17 of 26 people)
  • 2 - 5 years: 62.0% - (25 of 40 people)
  • 5 - 10 years: 79.0% - (23 of 29 people)
  • 10+ years: 66.0% - (16 of 24 people)
  • not specified: 0.0% - (0 of 2 people)

Drug effectiveness by gender:

Tramadol:
  • female: 30.0% - (35 of 115 people)
  • male: 20.0% - (10 of 48 people)
Omeprazole:
  • female: 58.0% - (69 of 117 people)
  • male: 58.0% - (28 of 48 people)

Drug effectiveness by age:

Tramadol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (3 of 3 people)
  • 20-29: 50.0% - (4 of 8 people)
  • 30-39: 40.0% - (10 of 25 people)
  • 40-49: 17.0% - (8 of 45 people)
  • 50-59: 26.0% - (10 of 38 people)
  • 60+: 22.0% - (10 of 44 people)
Omeprazole:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 33.0% - (1 of 3 people)
  • 20-29: 50.0% - (4 of 8 people)
  • 30-39: 48.0% - (12 of 25 people)
  • 40-49: 47.0% - (21 of 44 people)
  • 50-59: 70.0% - (28 of 40 people)
  • 60+: 68.0% - (31 of 45 people)

Most common drug interactions over time *:

< 1 month:
  • confusional state
  • vomiting
  • pneumonia
  • neutropenia
  • anaemia
  • thrombocytopenia
  • sepsis
  • pyrexia
  • dyspnoea
  • abdominal pain upper
1 - 6 months:
  • vomiting
  • abdominal pain
  • serotonin syndrome
  • pain
  • burning sensation
  • paraesthesia
  • pyrexia
  • dehydration
  • myalgia
  • septic shock
6 - 12 months:
  • depression
  • nausea
  • constipation
  • bone pain
  • fibromyalgia
  • rls
  • vomiting
  • multiple fractures
  • osteoporosis
  • pain
1 - 2 years:
  • confusional state
  • depression
  • malaise
  • dizziness
  • palpitations
  • hyperhidrosis
  • loss of consciousness
  • tongue biting
  • muscle rigidity
  • osteoporosis
2 - 5 years:
  • depression
  • dizziness
  • headache
  • anxiety
  • suicidal ideation
  • pyrexia
  • visual impairment
  • convulsion
  • asthenia
  • malaise
5 - 10 years:
  • hyperhidrosis
  • feeling hot
  • tinnitus
  • drug ineffective
  • fibromyalgia
  • pain
  • asthma
  • coagulopathy
  • dementia
  • lung abscess
10+ years:
  • blister
  • depressed mood
  • self-injurious ideation
  • depression
  • headache - mixed tension migraine
  • lightheadedness - dizzy
  • shortness of breath
  • osteoporosis
  • anxiety
  • arthritis
not specified:
  • pain
  • nausea
  • fatigue
  • diarrhoea
  • arthralgia
  • dyspnoea
  • headache
  • fall
  • vomiting
  • anxiety

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • fatigue
  • arthralgia
  • diarrhoea
  • dyspnoea
  • headache
  • vomiting
  • anxiety
  • fall
male:
  • fatigue
  • dyspnoea
  • nausea
  • pain
  • arthralgia
  • diarrhoea
  • depression
  • pneumonia
  • dizziness
  • asthenia

Most common drug interactions by age *:

0-1:
  • leukocytoclastic vasculitis
  • muscular weakness
  • pain
  • pain of skin
  • proteinuria
  • renal failure acute
  • skin swelling
  • skin wrinkling
2-9:
  • sepsis
  • arthralgia
  • bone pain
  • respiratory failure
  • tumour lysis syndrome
  • pneumonia
  • renal failure
  • abdominal pain
  • somnolence
  • hypertension
10-19:
  • headache
  • rash
  • tremor
  • suicidal ideation
  • flushing
  • anxiety
  • hallucination, visual
  • confusional state
  • depression
  • emotional distress
20-29:
  • pain
  • diarrhoea
  • dyspnoea
  • cholecystitis chronic
  • anxiety
  • headache
  • nausea
  • depression
  • dizziness
  • abdominal pain
30-39:
  • headache
  • vomiting
  • arthralgia
  • pyrexia
  • depression
  • dizziness
  • fatigue
  • malaise
  • anxiety
  • convulsion
40-49:
  • pain
  • nausea
  • chest pain
  • depression
  • arthralgia
  • fatigue
  • back pain
  • headache
  • pain in extremity
  • vomiting
50-59:
  • pain
  • nausea
  • fatigue
  • diarrhoea
  • headache
  • dyspnoea
  • arthralgia
  • vomiting
  • fall
  • anxiety
60+:
  • pain
  • fall
  • nausea
  • dyspnoea
  • diarrhoea
  • fatigue
  • arthralgia
  • asthenia
  • vomiting
  • anaemia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Tramadol and Omeprazole?

Can you answer these questions?

More questions for: Tramadol, Omeprazole

You may be interested in these reviews

More reviews for: Tramadol, Omeprazole

On eHealthMe, Tramadol (tramadol hydrochloride) is often used to treat pain. Omeprazole (omeprazole) is often used to treat gastrooesophageal reflux disease. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.