Review: taking Tramadol and Vicodin together


Summary

Drug interactions are reported among people who take Tramadol and Vicodin together. This review analyzes the effectiveness and drug interactions between Tramadol and Vicodin. It is created by eHealthMe based on reports of 6,908 people who take the same drugs from FDA and social media, and is updated regularly.

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Tramadol

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol 73,714 users)

Vicodin

Vicodin has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. (latest outcomes from Vicodin 45,484 users)

On Sep, 15, 2016

6,908 people who take Tramadol, Vicodin are studied.


Number of reports submitted per year:

Tramadol and Vicodin drug interactions.

Drug effectiveness over time:

Tramadol:
  • < 1 month: 20.0% - (7 of 35 people)
  • 1 - 6 months: 12.0% - (4 of 31 people)
  • 6 - 12 months: 0.0% - (0 of 24 people)
  • 1 - 2 years: 21.0% - (9 of 41 people)
  • 2 - 5 years: 28.0% - (12 of 42 people)
  • 5 - 10 years: 27.0% - (5 of 18 people)
  • 10+ years: 28.0% - (2 of 7 people)
  • not specified: 0.0% - (0 of 0 people)
Vicodin:
  • < 1 month: 48.0% - (18 of 37 people)
  • 1 - 6 months: 36.0% - (9 of 25 people)
  • 6 - 12 months: 35.0% - (7 of 20 people)
  • 1 - 2 years: 26.0% - (9 of 34 people)
  • 2 - 5 years: 48.0% - (24 of 50 people)
  • 5 - 10 years: 44.0% - (11 of 25 people)
  • 10+ years: 44.0% - (4 of 9 people)
  • not specified: 100.0% - (2 of 2 people)

Drug effectiveness by gender:

Tramadol:
  • female: 21.0% - (30 of 137 people)
  • male: 14.0% - (9 of 61 people)
Vicodin:
  • female: 45.0% - (65 of 143 people)
  • male: 32.0% - (19 of 59 people)

Drug effectiveness by age:

Tramadol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 30.0% - (6 of 20 people)
  • 30-39: 20.0% - (9 of 45 people)
  • 40-49: 15.0% - (8 of 51 people)
  • 50-59: 17.0% - (9 of 51 people)
  • 60+: 22.0% - (7 of 31 people)
Vicodin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 40.0% - (8 of 20 people)
  • 30-39: 46.0% - (22 of 47 people)
  • 40-49: 47.0% - (25 of 53 people)
  • 50-59: 38.0% - (19 of 50 people)
  • 60+: 31.0% - (10 of 32 people)

Most common drug interactions over time *:

< 1 month:
  • chest pain
  • loss of consciousness
  • cardiac arrest
  • drug ineffective
  • dyspnoea
  • dizziness
  • intervertebral disc protrusion
  • depression
  • pain
  • pain in extremity
1 - 6 months:
  • pain
  • depression
  • injury
  • drug ineffective
  • dizziness
  • mental status changes
  • nausea
  • dyspnoea
  • headache
  • anxiety
6 - 12 months:
  • dizziness
  • depression
  • disorientation
  • fatigue
  • hypotension
  • loss of consciousness
  • mental status changes
  • post-thoracotomy pain syndrome
  • anxiety
  • fall
1 - 2 years:
  • chest pain
  • headache
  • injury
  • depression
  • myocardial infarction
  • arthritis
  • helicobacter infection
  • hypoaesthesia
  • insomnia
  • migraine
2 - 5 years:
  • fatigue
  • chronic pain
  • neuropathy
  • anxiety
  • depression
  • dizziness
  • nausea
  • vertigo
  • suicidal ideation
  • headache
5 - 10 years:
  • anxiety
  • depression
  • breast cancer female
  • gastroparesis
  • loss of consciousness
  • nausea
  • pain
  • suicidal ideation
  • emotional distress
  • esophageal spasm
10+ years:
  • eye floaters
  • fatigue - chronic
  • high blood sugar
  • numbness in feet
  • pain
  • po2 increased
  • sweating - excessive
  • tearing - increased
  • weight gain poor
  • abdominal pain
not specified:
  • pain
  • nausea
  • anxiety
  • back pain
  • fatigue
  • dyspnoea
  • arthralgia
  • fall
  • depression
  • headache

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • anxiety
  • back pain
  • fatigue
  • fall
  • arthralgia
  • headache
  • dyspnoea
  • depression
male:
  • pain
  • anxiety
  • nausea
  • dyspnoea
  • back pain
  • fatigue
  • depression
  • asthenia
  • drug ineffective
  • chest pain

Most common drug interactions by age *:

0-1:
  • cardio-respiratory arrest
  • convulsion
  • apnoea
  • coma
  • accidental drug intake by child
  • death
  • foetal exposure during pregnancy
  • abdominal distension
  • abdominal pain upper
  • accidental exposure
2-9:
  • abdominal pain
  • actinic keratosis
  • anaemia
  • appendicitis
  • bone disorder
  • cardiac failure congestive
  • cardiac murmur
  • cardiomyopathy
  • carpal tunnel syndrome
  • cerebral calcification
10-19:
  • cholecystitis chronic
  • pain
  • nausea
  • gallbladder disorder
  • deep vein thrombosis
  • vomiting
  • abdominal pain
  • injury
  • cholelithiasis
  • anxiety
20-29:
  • pain
  • injury
  • anxiety
  • deep vein thrombosis
  • pulmonary embolism
  • depression
  • nausea
  • cholelithiasis
  • cholecystitis chronic
  • emotional distress
30-39:
  • pain
  • anxiety
  • depression
  • nausea
  • headache
  • dizziness
  • deep vein thrombosis
  • pain in extremity
  • arthralgia
  • chest pain
40-49:
  • pain
  • back pain
  • nausea
  • depression
  • arthralgia
  • anxiety
  • headache
  • chest pain
  • fatigue
  • pain in extremity
50-59:
  • pain
  • anxiety
  • fatigue
  • nausea
  • headache
  • insomnia
  • fall
  • arthralgia
  • back pain
  • depression
60+:
  • pain
  • fall
  • dyspnoea
  • back pain
  • nausea
  • fatigue
  • anxiety
  • diarrhoea
  • asthenia
  • arthralgia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Tramadol (tramadol hydrochloride) is often used to treat pain. Vicodin (acetaminophen; hydrocodone bitartrate) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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