Review: taking Unisom and Prozac together


Summary

Drug interactions are reported among people who take Unisom and Prozac together. This review analyzes the effectiveness and drug interactions between Unisom and Prozac. It is created by eHealthMe based on reports of 216 people who take the same drugs from FDA and social media, and is updated regularly.

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Unisom

Unisom has active ingredients of doxylamine succinate. It is often used in insomnia. (latest outcomes from Unisom 1,362 users)

Prozac

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. (latest outcomes from Prozac 55,554 users)

On Sep, 16, 2016

216 people who take Unisom, Prozac are studied.


Number of reports submitted per year:

Unisom and Prozac drug interactions.

Drug effectiveness over time:

Unisom:
  • < 1 month: 50.0% - (1 of 2 people)
  • 1 - 6 months: 0.0% - (0 of 3 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Prozac:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 75.0% - (3 of 4 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 3 people)
  • 2 - 5 years: 50.0% - (1 of 2 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Unisom:
  • female: 20.0% - (1 of 5 people)
  • male: 50.0% - (1 of 2 people)
Prozac:
  • female: 40.0% - (4 of 10 people)
  • male: 100.0% - (2 of 2 people)

Drug effectiveness by age:

Unisom:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 0.0% - (0 of 2 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 2 people)
Prozac:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 0.0% - (0 of 4 people)
  • 40-49: 66.0% - (2 of 3 people)
  • 50-59: 100.0% - (1 of 1 people)
  • 60+: 50.0% - (1 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • frequent or urgent urination
  • muscle pain
  • restless legs syndrome
  • sleep disorder due to general medical condition, insomnia type
  • blood pressure decreased
  • blood pressure increased
  • chest pain
  • completed suicide
  • depression
  • dizziness
1 - 6 months:
  • frequent or urgent urination
  • muscle pain
  • restless legs syndrome
  • sleep disorder due to general medical condition, insomnia type
1 - 2 years:
  • akathisia
  • drug ineffective
  • hepatocellular damage
  • multiple drug overdose
  • nausea
  • suicide attempt
2 - 5 years:
  • suicide attempt
  • abdominal pain lower
  • drug ineffective
  • hepatocellular damage
  • multiple drug overdose
  • nausea
  • ovarian cysts
  • polycystic ovarian syndrome (pcos)
5 - 10 years:
  • abdominal pain lower
  • ovarian cysts
  • polycystic ovarian syndrome (pcos)
not specified:
  • completed suicide
  • drug abuse
  • unresponsive to stimuli
  • pain in extremity
  • anaemia
  • pneumonia
  • arthropathy
  • asthenia
  • muscle spasms
  • headache

Most common drug interactions by gender *:

female:
  • drug abuse
  • completed suicide
  • cardiac arrest
  • cardio-respiratory arrest
  • respiratory arrest
  • unresponsive to stimuli
  • accidental death
  • death
  • malaise
  • pulmonary oedema
male:
  • completed suicide
  • overdose
  • asthenia
  • cardiomegaly
  • dyspnoea
  • ejection fraction decreased
  • haemoptysis
  • hyperhidrosis
  • pain
  • pneumonia

Most common drug interactions by age *:

0-1:
  • brain malformation
  • cerebral ventricle dilatation
  • congenital central nervous system anomaly
  • foetal exposure during pregnancy
  • plagiocephaly
  • polyhydramnios
  • seizure like phenomena
10-19:
  • allodynia
  • death
  • skin maceration
  • wound
  • cardio-respiratory arrest
  • completed suicide
20-29:
  • unresponsive to stimuli
  • pulmonary oedema
  • accidental death
  • drug screen positive
  • malaise
  • vomiting
  • pulmonary congestion
  • coronary artery occlusion
  • body temperature increased
  • cardiac arrest
30-39:
  • drug abuse
  • death
  • cardio-respiratory arrest
  • abdominal pain lower
  • completed suicide
  • akathisia
  • abdominal distension
  • abdominal pain upper
  • asthenia
  • blister
40-49:
  • anaemia
  • colitis
  • haematochezia
  • muscular weakness
  • pain in extremity
  • sensation of heaviness
  • balance disorder
  • dizziness
  • abdominal distension
  • abdominal pain
50-59:
  • completed suicide
  • cardiac arrest
  • respiratory arrest
  • cardio-respiratory arrest
  • death
  • pneumonia
  • suicide attempt
  • depression
  • fatigue
  • mental disorder
60+:
  • anaemia
  • arthropathy
  • muscle spasms
  • pain in extremity
  • cardiomegaly
  • musculoskeletal pain
  • osteoarthritis
  • overdose
  • dizziness
  • dyspnoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Unisom (doxylamine succinate) is often used to treat insomnia. Prozac (fluoxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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