Review: taking Valium and Benadryl together


Summary

Drug interactions are reported among people who take Valium and Benadryl together. This review analyzes the effectiveness and drug interactions between Valium and Benadryl. It is created by eHealthMe based on reports of 2,332 people who take the same drugs from FDA and social media, and is updated regularly.

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Valium

Valium has active ingredients of diazepam. It is often used in stress and anxiety. (latest outcomes from Valium 29,527 users)

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Benadryl 43,259 users)

On Sep, 18, 2016

2,332 people who take Valium, Benadryl are studied.


Number of reports submitted per year:

Valium and Benadryl drug interactions.

Drug effectiveness over time:

Valium:
  • < 1 month: 37.0% - (6 of 16 people)
  • 1 - 6 months: 25.0% - (1 of 4 people)
  • 6 - 12 months: 0.0% - (0 of 2 people)
  • 1 - 2 years: 25.0% - (2 of 8 people)
  • 2 - 5 years: 50.0% - (4 of 8 people)
  • 5 - 10 years: 50.0% - (3 of 6 people)
  • 10+ years: 100.0% - (2 of 2 people)
  • not specified: 33.0% - (1 of 3 people)
Benadryl:
  • < 1 month: 25.0% - (4 of 16 people)
  • 1 - 6 months: 0.0% - (0 of 6 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 50.0% - (1 of 2 people)
  • 2 - 5 years: 25.0% - (2 of 8 people)
  • 5 - 10 years: 66.0% - (4 of 6 people)
  • 10+ years: 100.0% - (4 of 4 people)
  • not specified: 0.0% - (0 of 2 people)

Drug effectiveness by gender:

Valium:
  • female: 34.0% - (11 of 32 people)
  • male: 47.0% - (8 of 17 people)
Benadryl:
  • female: 41.0% - (13 of 31 people)
  • male: 12.0% - (2 of 16 people)

Drug effectiveness by age:

Valium:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 1 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 33.0% - (3 of 9 people)
  • 30-39: 40.0% - (6 of 15 people)
  • 40-49: 44.0% - (4 of 9 people)
  • 50-59: 30.0% - (3 of 10 people)
  • 60+: 75.0% - (3 of 4 people)
Benadryl:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 1 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 33.0% - (3 of 9 people)
  • 30-39: 42.0% - (6 of 14 people)
  • 40-49: 11.0% - (1 of 9 people)
  • 50-59: 33.0% - (3 of 9 people)
  • 60+: 50.0% - (2 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • pain
  • renal failure
  • anxiety
  • chest pain
  • multi-organ failure
  • dizziness
  • headache
  • injury
  • nausea
  • death
1 - 6 months:
  • vision blurred
  • muscle tightness
  • acute respiratory distress syndrome
  • anxiety
  • blood bilirubin increased
  • chest tightness
  • diaphoresis
  • dysphagia
  • flushing
  • headache
6 - 12 months:
  • malaise
  • anhedonia
  • fever
  • inflammatory bowel disease
  • nausea postoperative
  • pancreatic pseudocyst
  • pulmonary embolism
  • tardive dyskinesia
  • cough
  • deep vein thrombosis
1 - 2 years:
  • fatigue
  • dizziness
  • insomnia
  • rash
  • back pain
  • constipation
  • hyperlipidaemia
  • loss of libido
  • nausea
  • restlessness
2 - 5 years:
  • constipation
  • anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension
  • burning eyes
  • chronic pain
  • chronic pancreatitis
  • chronic sinusitis
  • cognitive deterioration
  • depression
  • diarrhea
  • dry mouth
5 - 10 years:
  • chest tightness
  • diaphoresis
  • flushing
  • headache
  • hypertension aggravated
  • muscle tightness
  • nervousness
  • reactive arthritis
  • skin burning sensation
  • tachycardia
10+ years:
  • folliculitis
  • insomnia
  • rash
  • adjustment disorder with mixed anxiety and depressed mood
  • adrenal mass
  • anhidrosis
  • appetite - decreased
  • arthritis
  • back pain
  • blepharitis
not specified:
  • pain
  • headache
  • anxiety
  • nausea
  • fatigue
  • drug abuse
  • dyspnoea
  • fall
  • depression
  • insomnia

Most common drug interactions by gender *:

female:
  • pain
  • headache
  • nausea
  • fall
  • dyspnoea
  • anxiety
  • fatigue
  • insomnia
  • back pain
  • drug abuse
male:
  • anxiety
  • pain
  • headache
  • drug abuse
  • fatigue
  • nausea
  • depression
  • pyrexia
  • back pain
  • insomnia

Most common drug interactions by age *:

0-1:
  • constipation
  • vomiting
  • diarrhoea
  • hypoxia
  • tachycardia
  • tachypnoea
  • hypernatraemia
  • decreased appetite
  • diabetes insipidus
  • feeding disorder
2-9:
  • dyskinesia
  • dystonia
  • oculogyric crisis
  • aphasia
  • akinesia
  • dehydration
  • epidermal necrolysis
  • haemorrhagic stroke
  • pyrexia
  • thrombocytopenia
10-19:
  • completed suicide
  • insomnia
  • drug abuse
  • hypotension
  • overdose
  • cardiac arrest
  • drug ineffective
  • acute respiratory distress syndrome
  • blood bilirubin increased
  • death
20-29:
  • drug abuse
  • death
  • pyrexia
  • anxiety
  • pain
  • urticaria
  • cardiac arrest
  • mental disorder
  • poisoning
  • abdominal pain
30-39:
  • drug abuse
  • headache
  • pain
  • nausea
  • death
  • vomiting
  • fatigue
  • weight decreased
  • cardio-respiratory arrest
  • insomnia
40-49:
  • pain
  • depression
  • back pain
  • headache
  • nausea
  • drug abuse
  • asthenia
  • anxiety
  • vomiting
  • fatigue
50-59:
  • pain
  • anxiety
  • nausea
  • drug abuse
  • fall
  • headache
  • chest pain
  • depression
  • insomnia
  • renal failure acute
60+:
  • dyspnoea
  • pain
  • fatigue
  • hypotension
  • fall
  • anxiety
  • diarrhoea
  • headache
  • nausea
  • osteonecrosis of jaw

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Valium and Benadryl?

Can you answer these questions?

More questions for: Valium, Benadryl

You may be interested in these reviews

More reviews for: Valium, Benadryl

On eHealthMe, Valium (diazepam) is often used to treat stress and anxiety. Benadryl (diphenhydramine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.