Review: taking Valium and Hydroxyzine hydrochloride together


Summary

Drug interactions are reported among people who take Valium and Hydroxyzine hydrochloride together. This review analyzes the effectiveness and drug interactions between Valium and Hydroxyzine hydrochloride. It is created by eHealthMe based on reports of 1,575 people who take the same drugs from FDA and social media, and is updated regularly.

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Valium

Valium has active ingredients of diazepam. It is often used in stress and anxiety. (latest outcomes from Valium 29,527 users)

Hydroxyzine Hydrochloride

Hydroxyzine hydrochloride has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. (latest outcomes from Hydroxyzine hydrochloride 1,770 users)

On Sep, 15, 2016

1,575 people who take Valium, Hydroxyzine Hydrochloride are studied.


Number of reports submitted per year:

Valium and Hydroxyzine hydrochloride drug interactions.

Drug effectiveness over time:

Valium:
  • < 1 month: 50.0% - (2 of 4 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 33.0% - (1 of 3 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Hydroxyzine Hydrochloride:
  • < 1 month: 0.0% - (0 of 3 people)
  • 1 - 6 months: 20.0% - (1 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 33.0% - (1 of 3 people)
  • 2 - 5 years: 0.0% - (0 of 2 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Valium:
  • female: 10.0% - (1 of 10 people)
  • male: 60.0% - (3 of 5 people)
Hydroxyzine Hydrochloride:
  • female: 20.0% - (2 of 10 people)
  • male: 0.0% - (0 of 5 people)

Drug effectiveness by age:

Valium:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 25.0% - (2 of 8 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 40.0% - (2 of 5 people)
  • 60+: 0.0% - (0 of 2 people)
Hydroxyzine Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 12.0% - (1 of 8 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 20.0% - (1 of 5 people)
  • 60+: 0.0% - (0 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • drug rash with eosinophilia and systemic symptoms
  • pyrexia
  • coma
  • altered state of consciousness
  • blood albumin decreased
  • aspartate aminotransferase increased
  • gamma-glutamyltransferase increased
  • hepatocellular injury
  • organising pneumonia
  • lymphocyte stimulation test positive
1 - 6 months:
  • dehydration
  • abnormal behaviour
  • agitation
  • decreased appetite
  • somnolence
  • disturbance in attention
  • renal failure acute
  • circadian rhythm sleep disorder
  • convulsion
  • general physical health deterioration
6 - 12 months:
  • dehydration
  • anorexia
  • headache
  • pallor
  • serotonin syndrome
  • tremor
  • weight decreased
  • cerebellar syndrome
  • clonic convulsion
  • foetal exposure during pregnancy
1 - 2 years:
  • serotonin syndrome
  • diabetes mellitus
  • diabetic ketoacidosis
  • alveolar osteitis
  • anxiety
  • arthropathy
  • bacterial test positive
  • blood cholesterol increased
  • blood potassium decreased
  • drug dependence
2 - 5 years:
  • abdominal pain upper
  • adverse event
  • anorexia
  • anxiety
  • drug withdrawal syndrome
  • hypertension
  • influenza like illness
  • loss of consciousness
  • sensory disturbance
  • social avoidant behaviour
5 - 10 years:
  • loss of consciousness
  • lumbar vertebral fracture
  • muscle spasms
  • leukopenia
  • anxiety
  • convulsion
  • discomfort
  • fractured coccyx
  • fractured sacrum
10+ years:
  • headache
  • muscle pain
  • photophobia
  • pyrexia
  • weight gain - unintentional
not specified:
  • anxiety
  • depression
  • nausea
  • headache
  • dyspnoea
  • pain
  • fall
  • back pain
  • dizziness
  • insomnia

Most common drug interactions by gender *:

female:
  • depression
  • anxiety
  • dyspnoea
  • nausea
  • headache
  • fall
  • pain
  • hypertension
  • arthralgia
  • insomnia
male:
  • anxiety
  • back pain
  • headache
  • tremor
  • pain
  • fatigue
  • dizziness
  • depression
  • nausea
  • hypoaesthesia

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • drug withdrawal syndrome neonatal
  • tremor
  • foetal growth restriction
  • respiratory distress
  • withdrawal syndrome
  • drug exposure during pregnancy
  • growth retardation
  • foetal malnutrition
  • hypotonia neonatal
2-9:
  • agitation
  • convulsion
  • hyperthermia
  • tachycardia
  • abnormal behaviour
  • aggression
  • altered state of consciousness
  • blood creatine phosphokinase increased
  • cytolytic hepatitis
  • dehydration
10-19:
  • drug rash with eosinophilia and systemic symptoms
  • completed suicide
  • cardio-respiratory arrest
  • cardiac arrest
  • respiratory arrest
  • electrocardiogram qt prolonged
  • diabetes insipidus
  • electrolyte imbalance
  • lymphocyte stimulation test positive
  • poisoning
20-29:
  • drug withdrawal syndrome
  • suicidal ideation
  • tremor
  • pyrexia
  • anxiety
  • cardiac arrest
  • insomnia
  • vomiting
  • cardiac tamponade
  • fatigue
30-39:
  • anxiety
  • hypertension
  • pain
  • nausea
  • sinusitis
  • arthralgia
  • depression
  • headache
  • drug dependence
  • bronchitis
40-49:
  • depression
  • fall
  • headache
  • back pain
  • anxiety
  • weight increased
  • nausea
  • constipation
  • dizziness
  • pain
50-59:
  • depression
  • anxiety
  • insomnia
  • dyspnoea
  • weight decreased
  • pneumonia
  • cardiac failure congestive
  • fall
  • oedema peripheral
  • nausea
60+:
  • dyspnoea
  • fall
  • headache
  • chest pain
  • back pain
  • pain
  • anxiety
  • fatigue
  • dizziness
  • hypotension

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Valium (diazepam) is often used to treat stress and anxiety. Hydroxyzine hydrochloride (hydroxyzine hydrochloride) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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