Review: taking Valium and Hydroxyzine hydrochloride together


Summary

Drug interactions are reported among people who take Valium and Hydroxyzine hydrochloride together. This review analyzes the effectiveness and drug interactions between Valium and Hydroxyzine hydrochloride. It is created by eHealthMe based on reports of 1,250 people who take the same drugs from FDA and social media, and is updated regularly.

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Valium

Valium has active ingredients of diazepam. It is often used in stress and anxiety. (latest outcomes from Valium 23,828 users)

Hydroxyzine Hydrochloride

Hydroxyzine hydrochloride has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. (latest outcomes from Hydroxyzine hydrochloride 1,397 users)

On Aug, 22, 2016

1,250 people who take Valium, Hydroxyzine Hydrochloride are studied.


Number of reports submitted per year:

Valium and Hydroxyzine hydrochloride drug interactions.

Drug effectiveness over time:

Valium:
  • < 1 month: 50.0% - (2 of 4 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 33.0% - (1 of 3 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Hydroxyzine Hydrochloride:
  • < 1 month: 0.0% - (0 of 3 people)
  • 1 - 6 months: 20.0% - (1 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 33.0% - (1 of 3 people)
  • 2 - 5 years: 0.0% - (0 of 2 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Valium:
  • female: 10.0% - (1 of 10 people)
  • male: 60.0% - (3 of 5 people)
Hydroxyzine Hydrochloride:
  • female: 20.0% - (2 of 10 people)
  • male: 0.0% - (0 of 5 people)

Drug effectiveness by age:

Valium:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 25.0% - (2 of 8 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 40.0% - (2 of 5 people)
  • 60+: 0.0% - (0 of 2 people)
Hydroxyzine Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 12.0% - (1 of 8 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 20.0% - (1 of 5 people)
  • 60+: 0.0% - (0 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • drug rash with eosinophilia and systemic symptoms
  • pyrexia
  • coma
  • organising pneumonia
  • lymphocyte stimulation test positive
  • stevens johnson syndrome
  • cardio-respiratory arrest
  • constipation
  • hepatic function abnormal
  • insomnia
1 - 6 months:
  • dehydration
  • abnormal behaviour
  • agitation
  • decreased appetite
  • somnolence
  • disturbance in attention
  • renal failure acute
  • circadian rhythm sleep disorder
  • convulsion
  • general physical health deterioration
6 - 12 months:
  • dehydration
  • anorexia
  • headache
  • pallor
  • serotonin syndrome
  • tremor
  • weight decreased
  • cerebellar syndrome
  • clonic convulsion
  • orthostatic hypotension
1 - 2 years:
  • serotonin syndrome
  • diabetes mellitus
  • diabetic ketoacidosis
  • bacterial test positive
  • blood cholesterol increased
  • blood potassium decreased
  • fungal test positive
  • hyperlipidaemia
  • multiple injuries
  • muscle pain
2 - 5 years:
  • abdominal pain upper
  • adverse event
  • anorexia
  • anxiety
  • drug withdrawal syndrome
  • hypertension
  • influenza like illness
  • loss of consciousness
  • sensory disturbance
  • social avoidant behaviour
5 - 10 years:
  • leukopenia
  • anxiety
  • convulsion
  • discomfort
  • fractured coccyx
  • fractured sacrum
  • loss of consciousness
  • lumbar vertebral fracture
  • muscle spasms
10+ years:
  • muscle pain
  • weight gain - unintentional
not specified:
  • anxiety
  • depression
  • dyspnoea
  • nausea
  • headache
  • pain
  • fall
  • back pain
  • dizziness
  • insomnia

Most common drug interactions by gender *:

female:
  • depression
  • anxiety
  • dyspnoea
  • nausea
  • headache
  • fall
  • hypertension
  • pain
  • arthralgia
  • dizziness
male:
  • anxiety
  • back pain
  • headache
  • pain
  • tremor
  • depression
  • fatigue
  • hypoaesthesia
  • dizziness
  • insomnia

Most common drug interactions by age *:

0-1:
  • drug withdrawal syndrome neonatal
  • foetal exposure during pregnancy
  • foetal growth restriction
  • respiratory distress
  • tremor
  • withdrawal syndrome
  • drug exposure during pregnancy
  • foetal malnutrition
  • hypotonia neonatal
  • hypoventilation
2-9:
  • agitation
  • convulsion
  • hyperthermia
  • tachycardia
  • abnormal behaviour
  • aggression
  • altered state of consciousness
  • blood creatine phosphokinase increased
  • cytolytic hepatitis
  • dehydration
10-19:
  • drug rash with eosinophilia and systemic symptoms
  • completed suicide
  • cardio-respiratory arrest
  • electrocardiogram qt prolonged
  • cardiac arrest
  • respiratory arrest
  • diabetes insipidus
  • electrolyte imbalance
  • lymphocyte stimulation test positive
  • affective disorder
20-29:
  • suicidal ideation
  • pyrexia
  • drug withdrawal syndrome
  • anxiety
  • insomnia
  • tremor
  • vomiting
  • cardiac arrest
  • cardiac tamponade
  • pericardial effusion
30-39:
  • anxiety
  • hypertension
  • pain
  • nausea
  • arthralgia
  • depression
  • sinusitis
  • bronchitis
  • dysarthria
  • agitation
40-49:
  • fall
  • back pain
  • depression
  • headache
  • anxiety
  • dizziness
  • weight increased
  • constipation
  • pain
  • insomnia
50-59:
  • depression
  • anxiety
  • insomnia
  • weight decreased
  • dyspnoea
  • cardiac failure congestive
  • pneumonia
  • oedema peripheral
  • nausea
  • headache
60+:
  • dyspnoea
  • fall
  • chest pain
  • headache
  • back pain
  • anxiety
  • fatigue
  • hypotension
  • pain
  • dizziness

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Valium (diazepam) is often used to treat stress and anxiety. Hydroxyzine hydrochloride (hydroxyzine hydrochloride) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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