Review: taking Valium and Methadone hydrochloride together


Summary

Drug interactions are reported among people who take Valium and Methadone hydrochloride together. This review analyzes the effectiveness and drug interactions between Valium and Methadone hydrochloride. It is created by eHealthMe based on reports of 2,644 people who take the same drugs from FDA and social media, and is updated regularly.

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Valium

Valium has active ingredients of diazepam. It is often used in stress and anxiety. (latest outcomes from Valium 23,828 users)

Methadone Hydrochloride

Methadone hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. (latest outcomes from Methadone hydrochloride 2,951 users)

On Aug, 24, 2016

2,644 people who take Valium, Methadone Hydrochloride are studied.


Number of reports submitted per year:

Valium and Methadone hydrochloride drug interactions.

Drug effectiveness over time:

Valium:
  • < 1 month: 42.0% - (3 of 7 people)
  • 1 - 6 months: 55.0% - (5 of 9 people)
  • 6 - 12 months: 66.0% - (2 of 3 people)
  • 1 - 2 years: 33.0% - (1 of 3 people)
  • 2 - 5 years: 28.0% - (2 of 7 people)
  • 5 - 10 years: 33.0% - (1 of 3 people)
  • 10+ years: 54.0% - (6 of 11 people)
  • not specified: 100.0% - (1 of 1 people)
Methadone Hydrochloride:
  • < 1 month: 40.0% - (2 of 5 people)
  • 1 - 6 months: 50.0% - (2 of 4 people)
  • 6 - 12 months: 83.0% - (5 of 6 people)
  • 1 - 2 years: 80.0% - (4 of 5 people)
  • 2 - 5 years: 58.0% - (7 of 12 people)
  • 5 - 10 years: 42.0% - (3 of 7 people)
  • 10+ years: 50.0% - (3 of 6 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Valium:
  • female: 50.0% - (11 of 22 people)
  • male: 45.0% - (10 of 22 people)
Methadone Hydrochloride:
  • female: 62.0% - (15 of 24 people)
  • male: 54.0% - (12 of 22 people)

Drug effectiveness by age:

Valium:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 63.0% - (7 of 11 people)
  • 30-39: 36.0% - (4 of 11 people)
  • 40-49: 38.0% - (5 of 13 people)
  • 50-59: 55.0% - (5 of 9 people)
  • 60+: 0.0% - (0 of 0 people)
Methadone Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 66.0% - (8 of 12 people)
  • 30-39: 58.0% - (7 of 12 people)
  • 40-49: 53.0% - (7 of 13 people)
  • 50-59: 55.0% - (5 of 9 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • vomiting
  • headache
  • dysarthria
  • malaise
  • hyperhidrosis
  • oropharyngeal pain
  • dysuria
  • somnolence
  • crohn's disease
  • diffuse alveolar damage
1 - 6 months:
  • drug ineffective
  • psychomotor retardation
  • sopor
  • vomiting
  • death
  • dysgeusia
  • headache
  • malaise
  • nausea
  • alanine aminotransferase increased
6 - 12 months:
  • back injury
  • arnold-chiari malformation
  • sciatic nerve neuropathy
  • abnormal behaviour
  • atrial septal defect
  • dental caries
  • depression
  • drug dependence
  • drug exposure during pregnancy
  • drug withdrawal syndrome neonatal
1 - 2 years:
  • dental caries
  • drug abuse
  • abnormal behaviour
  • depression
  • drug dependence
  • dysarthria
  • tooth abscess
  • overdose
  • cholecystitis acute
  • drug ineffective
2 - 5 years:
  • arnold-chiari malformation
  • back injury
  • sciatic nerve neuropathy
  • syncope
  • depression
  • electrocardiogram qt prolonged
  • abdominal pain
  • abnormal behaviour
  • aggression
  • anxiety
5 - 10 years:
  • confusional state
  • anxiety
  • bipolar disorder
  • renal failure
  • abnormal behaviour
  • aggression
  • chronic pain
  • depression
  • depression aggravated
  • mental disorder
10+ years:
  • drug withdrawal syndrome
  • depressed mood
  • renal failure
  • abasia
  • abdominal bloating
  • acarodermatitis
  • addiction
  • arthralgia
  • cardiac arrest
  • coma
not specified:
  • drug abuse
  • completed suicide
  • cardiac arrest
  • pain
  • respiratory arrest
  • death
  • drug toxicity
  • vomiting
  • cardio-respiratory arrest
  • headache

Most common drug interactions by gender *:

female:
  • pain
  • drug abuse
  • vomiting
  • headache
  • anxiety
  • depression
  • death
  • dizziness
  • constipation
  • cardiac arrest
male:
  • drug abuse
  • drug toxicity
  • pain
  • death
  • cardiac arrest
  • completed suicide
  • back pain
  • vomiting
  • drug ineffective
  • headache

Most common drug interactions by age *:

0-1:
  • nystagmus
  • visual acuity reduced
  • developmental delay
  • strabismus
  • congenital nystagmus
  • foetal exposure during pregnancy
  • optic nerve hypoplasia
  • maternal exposure during pregnancy
  • strabismus congenital
  • drug exposure during pregnancy
2-9:
  • nystagmus
  • developmental delay
  • drug exposure during pregnancy
  • strabismus
  • visual acuity reduced
  • congenital nystagmus
  • visual impairment
  • posture abnormal
  • drug withdrawal syndrome neonatal
  • maternal exposure during pregnancy
10-19:
  • hypotension
  • acute respiratory distress syndrome
  • blood bilirubin increased
  • hypernatraemia
  • pneumonia respiratory syncytial viral
  • pneumonitis
  • cardiac arrest
  • overdose
  • respiratory arrest
  • drug screen positive
20-29:
  • drug abuse
  • drug toxicity
  • completed suicide
  • respiratory arrest
  • overdose
  • cardiac arrest
  • cardio-respiratory arrest
  • multiple drug overdose
  • therapeutic agent toxicity
  • death
30-39:
  • arthralgia
  • drug abuse
  • completed suicide
  • pain in extremity
  • cardiac arrest
  • oedema peripheral
  • respiratory arrest
  • impaired healing
  • wound dehiscence
  • back pain
40-49:
  • pain
  • headache
  • depression
  • constipation
  • vomiting
  • anxiety
  • drug dependence
  • drug abuse
  • fatigue
  • dizziness
50-59:
  • drug abuse
  • completed suicide
  • cardiac arrest
  • death
  • respiratory arrest
  • dyspnoea
  • poisoning
  • pain
  • anxiety
  • cardio-respiratory arrest
60+:
  • cardiac arrest
  • respiratory arrest
  • death
  • completed suicide
  • pain
  • vomiting
  • dehydration
  • cardio-respiratory arrest
  • anxiety
  • fall

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Valium (diazepam) is often used to treat stress and anxiety. Methadone hydrochloride (methadone hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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