Review: taking Valium and Naloxone together


Drug interactions are reported among people who take Valium and Naloxone together. This review analyzes the effectiveness and drug interactions between Valium and Naloxone. It is created by eHealthMe based on reports of 110 people who take the same drugs from FDA and social media, and is updated regularly.

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Valium has active ingredients of diazepam. It is often used in stress and anxiety. (latest outcomes from Valium 23,828 users)


Naloxone has active ingredients of naloxone hydrochloride. It is often used in pain. (latest outcomes from Naloxone 1,270 users)

On Aug, 24, 2016

110 people who take Valium, Naloxone are studied.

Number of reports submitted per year:

Valium and Naloxone drug interactions.

Most common drug interactions over time *:

< 1 month:
  • aspartate aminotransferase increased
  • hypokalaemia
  • liver carcinoma ruptured
  • abdominal pain
  • diarrhoea
  • hepatic failure
  • anaphylactic shock
  • polyarthritis
  • respiratory arrest
  • shock
not specified:
  • pain
  • anxiety
  • arthralgia
  • pain in extremity
  • rash
  • chest pain
  • osteonecrosis of jaw
  • dehydration
  • decreased interest
  • general physical health deterioration

Most common drug interactions by gender *:

  • pain
  • anxiety
  • metastases to bone
  • osteonecrosis of jaw
  • pain in extremity
  • fall
  • metastases to liver
  • cardiac arrest
  • hypotension
  • neoplasm malignant
  • arthralgia
  • pain
  • rash
  • anxiety
  • chest pain
  • paraesthesia
  • pain in extremity
  • diarrhoea
  • dyspepsia
  • pyrexia

Most common drug interactions by age *:

  • neonatal apnoeic attack
  • sedation
  • somnolence neonatal
  • autonomic failure syndrome
  • body temperature fluctuation
  • brain death
  • diabetes insipidus
  • drug screen positive
  • drug toxicity
  • hyperhidrosis
  • loss of consciousness
  • nosocomial infection
  • respiratory failure
  • alanine aminotransferase decreased
  • anion gap increased
  • ascites
  • aspartate aminotransferase increased
  • atelectasis
  • blood albumin decreased
  • blood alkaline phosphatase decreased
  • blood calcium decreased
  • blood chloride decreased
  • blood glucose increased
  • accidental overdose (non therapeutic agent or chemical)
  • accidental overdose (therapeutic agent)
  • agitation
  • blood creatine phosphokinase increased
  • cardiac arrest
  • cardio-respiratory arrest
  • depressed level of consciousness
  • disseminated intravascular coagulation
  • drug screen positive
  • dystonia
  • arthralgia
  • paraesthesia
  • coma
  • delirium
  • drug withdrawal syndrome
  • dyspepsia
  • ecchymosis
  • generalised oedema
  • hypoaesthesia
  • nephrogenic systemic fibrosis
  • pain in extremity
  • anxiety
  • pain
  • osteonecrosis of jaw
  • chest pain
  • diarrhoea
  • dizziness
  • decreased interest
  • dehydration
  • dyspnoea
  • anxiety
  • adrenal insufficiency
  • anaemia
  • anhedonia
  • breath odour
  • cachexia
  • exostosis
  • fistula discharge
  • injury
  • jaw fracture
  • cardiac arrest
  • anger
  • depressed mood
  • hallucination, auditory
  • hostility
  • hypertensive crisis
  • impaired self-care
  • coma
  • septic shock
  • bradypnoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Valium (diazepam) is often used to treat stress and anxiety. Naloxone (naloxone hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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