Review: taking Verapamil hydrochloride and Benadryl together


Summary

Drug interactions are reported among people who take Verapamil hydrochloride and Benadryl together. This review analyzes the effectiveness and drug interactions between Verapamil hydrochloride and Benadryl. It is created by eHealthMe based on reports of 398 people who take the same drugs from FDA and social media, and is updated regularly.

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Verapamil Hydrochloride

Verapamil hydrochloride has active ingredients of verapamil. It is often used in high blood pressure. (latest outcomes from Verapamil hydrochloride 2,828 users)

Benadryl

Benadryl has active ingredients of diphenhydramine. It is often used in hypersensitivity. (latest outcomes from Benadryl 29,241 users)

On Jul, 20, 2016

398 people who take Verapamil Hydrochloride, Benadryl are studied.


Number of reports submitted per year:

Verapamil hydrochloride and Benadryl drug interactions.

Drug effectiveness over time:

Verapamil Hydrochloride:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 100.0% - (1 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 50.0% - (1 of 2 people)
  • 5 - 10 years: 100.0% - (2 of 2 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Benadryl:
  • < 1 month: 50.0% - (1 of 2 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 66.0% - (2 of 3 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 100.0% - (2 of 2 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Verapamil Hydrochloride:
  • female: 100.0% - (2 of 2 people)
  • male: 60.0% - (3 of 5 people)
Benadryl:
  • female: 66.0% - (2 of 3 people)
  • male: 75.0% - (3 of 4 people)

Drug effectiveness by age:

Verapamil Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 50.0% - (1 of 2 people)
  • 40-49: 100.0% - (2 of 2 people)
  • 50-59: 100.0% - (1 of 1 people)
  • 60+: 0.0% - (0 of 1 people)
Benadryl:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 50.0% - (1 of 2 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 100.0% - (1 of 1 people)
  • 60+: 100.0% - (1 of 1 people)

Most common drug interactions over time *:

< 1 month:
  • asthenia
  • feeling of body temperature change
  • hallucination
  • headache
  • loss of consciousness
  • malnutrition
  • muscle spasms
  • muscular weakness
  • nausea
  • pain
1 - 6 months:
  • drowsiness
1 - 2 years:
  • death
  • dyspnoea
  • erythema
  • syncope
  • coma
  • flushing
  • haematocrit decreased
  • hypokalaemia
  • infusion related reaction
  • iron overload
2 - 5 years:
  • bradycardia
  • cardiac failure congestive
  • dyspnoea
  • fatigue
  • feeling abnormal
  • hypokalaemia
  • iron overload
  • kidney infection
  • lupus enteritis
  • lupus-like syndrome
5 - 10 years:
  • anger
  • dizziness (excl vertigo)
  • edema
  • nausea in the morning - females
10+ years:
  • ileus
  • anger
  • dizziness (excl vertigo)
  • edema
  • nausea in the morning - females
  • small intestinal obstruction
not specified:
  • nausea
  • dyspnoea
  • pain
  • asthenia
  • vomiting
  • depression
  • anxiety
  • arthralgia
  • chest pain
  • pain in extremity

Most common drug interactions by gender *:

female:
  • nausea
  • vomiting
  • dyspnoea
  • pain
  • chest pain
  • headache
  • status asthmaticus
  • back pain
  • migraine
  • pain in extremity
male:
  • asthenia
  • depression
  • fatigue
  • myalgia
  • anxiety
  • arthralgia
  • muscle spasms
  • weight decreased
  • nausea
  • dyspnoea

Most common drug interactions by age *:

10-19:
  • abdominal distension
  • blood bilirubin increased
  • vaginal haemorrhage
  • ascites
  • blood creatinine increased
  • blood lactate dehydrogenase increased
  • enterococcal bacteraemia
  • pathogen resistance
20-29:
  • cholecystitis chronic
  • gallbladder cholesterolosis
  • subclavian vein thrombosis
  • abdominal pain upper
  • nausea
  • infusion related reaction
  • pruritus
  • anaemia
  • anxiety
  • asthenia
30-39:
  • cardiac arrest
  • status asthmaticus
  • respiratory arrest
  • arthralgia
  • chest pain
  • drug toxicity
  • anxiety
  • coma
  • difficulty in walking
  • dyspnoea
40-49:
  • asthenia
  • hypothyroidism
  • myalgia
  • pain
  • pain in extremity
  • back pain
  • depression
  • fatigue
  • liver function test abnormal
  • oedema peripheral
50-59:
  • completed suicide
  • weight decreased
  • cholelithiasis
  • emotional distress
  • chest pain
  • dyspnoea
  • memory impairment
  • myocardial infarction
  • pain in extremity
  • palpitations
60+:
  • nausea
  • vomiting
  • dyspnoea
  • headache
  • asthenia
  • dizziness
  • chest pain
  • diarrhoea
  • cardiac arrest
  • hypotension

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Verapamil hydrochloride (verapamil) is often used to treat high blood pressure. Benadryl (diphenhydramine) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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