Review: taking Vistaril and Benadryl together


Summary

Drug interactions are reported among people who take Vistaril and Benadryl together. This review analyzes the effectiveness and drug interactions between Vistaril and Benadryl. It is created by eHealthMe based on reports of 1,732 people who take the same drugs from FDA and social media, and is updated regularly.

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Vistaril

Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. (latest outcomes from Vistaril 5,940 users)

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Benadryl 43,259 users)

On Sep, 19, 2016

1,732 people who take Vistaril, Benadryl are studied.


Number of reports submitted per year:

Vistaril and Benadryl drug interactions.

Drug effectiveness over time:

Vistaril:
  • < 1 month: 10.0% - (1 of 10 people)
  • 1 - 6 months: 11.0% - (1 of 9 people)
  • 6 - 12 months: 50.0% - (1 of 2 people)
  • 1 - 2 years: 0.0% - (0 of 2 people)
  • 2 - 5 years: 66.0% - (2 of 3 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 1 people)
Benadryl:
  • < 1 month: 0.0% - (0 of 7 people)
  • 1 - 6 months: 14.0% - (1 of 7 people)
  • 6 - 12 months: 100.0% - (2 of 2 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 40.0% - (2 of 5 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 25.0% - (1 of 4 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Vistaril:
  • female: 17.0% - (4 of 23 people)
  • male: 20.0% - (1 of 5 people)
Benadryl:
  • female: 27.0% - (6 of 22 people)
  • male: 25.0% - (1 of 4 people)

Drug effectiveness by age:

Vistaril:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 50.0% - (1 of 2 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 33.0% - (1 of 3 people)
  • 30-39: 0.0% - (0 of 9 people)
  • 40-49: 14.0% - (1 of 7 people)
  • 50-59: 25.0% - (1 of 4 people)
  • 60+: 33.0% - (1 of 3 people)
Benadryl:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 1 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 66.0% - (2 of 3 people)
  • 30-39: 11.0% - (1 of 9 people)
  • 40-49: 16.0% - (1 of 6 people)
  • 50-59: 50.0% - (2 of 4 people)
  • 60+: 33.0% - (1 of 3 people)

Most common drug interactions over time *:

< 1 month:
  • hypersensitivity
  • blood calcium decreased
  • dizziness
  • peripheral swelling
  • arteriosclerosis
  • cardiac arrest
  • dyspnoea
  • loss of consciousness
  • weight increased
  • acute myeloid leukaemia
1 - 6 months:
  • tremor
  • aggression
  • anaphylaxis
  • bone marrow failure
  • cerebrovascular accident
  • depressed mood
  • disorientation
  • dysarthria
  • hives
  • homicide
6 - 12 months:
  • convulsion
  • cardiac arrest
  • haemorrhage
  • infusion related reaction
  • abdominal pain upper
  • arthralgia
  • ascites
  • autonomic neuropathy
  • back injury
  • blood pressure systolic decreased
1 - 2 years:
  • convulsion
  • abdominal pain lower
  • cardiac arrest
  • haemorrhage
  • nephrogenic systemic fibrosis
  • agitation
  • ascites
  • blood pressure systolic decreased
  • bruxism
  • coagulopathy
2 - 5 years:
  • anxiety
  • anxiety disorder
  • bipolar disorder
  • crying
  • hypersensitivity
  • hysterectomy
  • insomnia
  • irregular heart beat
  • joint pain
  • tremor
10+ years:
  • breathing difficulty - lying down
  • breathing sounds
  • chronic pain
  • itching
  • abdominal pain lower
  • breast cancer
  • ovarian cysts
  • polycystic ovarian syndrome (pcos)
not specified:
  • fatigue
  • dyspnoea
  • nausea
  • pruritus
  • headache
  • arthralgia
  • pain
  • diarrhoea
  • vomiting
  • back pain

Most common drug interactions by gender *:

female:
  • dyspnoea
  • nausea
  • headache
  • pruritus
  • fatigue
  • arthralgia
  • back pain
  • pain
  • vomiting
  • anxiety
male:
  • fatigue
  • weight decreased
  • dyspnoea
  • diarrhoea
  • pyrexia
  • pruritus
  • nausea
  • rash
  • thrombocytopenia
  • drug abuse

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • abdominal pain
  • blood glucose increased
  • diarrhoea
  • urticaria
  • agitation
  • angioedema
  • apnoea
  • attention deficit/hyperactivity disorder
  • autism spectrum disorder
2-9:
  • diarrhoea
  • swelling face
  • cholecystitis acute
  • rash
  • pain in extremity
  • abdominal pain
  • atrial septal defect
  • cleft lip and palate
  • failure to thrive
  • holoprosencephaly
10-19:
  • rash
  • vomiting
  • blood bilirubin increased
  • histiocytosis haematophagic
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • pyrexia
  • drug abuse
  • rash erythematous
  • renal failure acute
20-29:
  • drug abuse
  • headache
  • blood pressure increased
  • dyspnoea
  • arthralgia
  • eczema
  • pain
  • loss of consciousness
  • lymphadenopathy
  • chest discomfort
30-39:
  • pruritus
  • abdominal pain
  • bronchitis
  • fatigue
  • contusion
  • fall
  • obesity
  • depression
  • joint swelling
  • mycosis fungoides
40-49:
  • pruritus
  • dyspnoea
  • fatigue
  • nausea
  • pyrexia
  • drug abuse
  • depression
  • vomiting
  • insomnia
  • arthralgia
50-59:
  • headache
  • dizziness
  • anxiety
  • dyspnoea
  • pain
  • nausea
  • back pain
  • cough
  • fall
  • pulmonary hypertension
60+:
  • fatigue
  • dyspnoea
  • diarrhoea
  • weight decreased
  • hypotension
  • fall
  • back pain
  • vomiting
  • arthralgia
  • headache

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Vistaril (hydroxyzine hydrochloride) is often used to treat stress and anxiety. Benadryl (diphenhydramine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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