Review: taking Vitamin b12 and Plavix together


Summary

Drug interactions are reported among people who take Vitamin b12 and Plavix together. This review analyzes the effectiveness and drug interactions between Vitamin b12 and Plavix. It is created by eHealthMe based on reports of 748 people who take the same drugs from FDA and social media, and is updated regularly.

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Vitamin B12

Vitamin b12 has active ingredients of cobalamin. It is often used in vitamin supplementation. (latest outcomes from Vitamin b12 23,231 users)

Plavix

Plavix has active ingredients of clopidogrel bisulfate. It is often used in stent. (latest outcomes from Plavix 101,521 users)

On Sep, 14, 2016

748 people who take Vitamin B12, Plavix are studied.


Number of reports submitted per year:

Vitamin b12 and Plavix drug interactions.

Drug effectiveness over time:

Vitamin B12:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 2 people)
  • 2 - 5 years: 16.0% - (1 of 6 people)
  • 5 - 10 years: 100.0% - (5 of 5 people)
  • 10+ years: 25.0% - (1 of 4 people)
  • not specified: 0.0% - (0 of 0 people)
Plavix:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 100.0% - (1 of 1 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 75.0% - (3 of 4 people)
  • 5 - 10 years: 100.0% - (4 of 4 people)
  • 10+ years: 50.0% - (2 of 4 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Vitamin B12:
  • female: 40.0% - (4 of 10 people)
  • male: 37.0% - (3 of 8 people)
Plavix:
  • female: 66.0% - (6 of 9 people)
  • male: 62.0% - (5 of 8 people)

Drug effectiveness by age:

Vitamin B12:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 100.0% - (2 of 2 people)
  • 50-59: 42.0% - (3 of 7 people)
  • 60+: 22.0% - (2 of 9 people)
Plavix:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 100.0% - (5 of 5 people)
  • 60+: 50.0% - (5 of 10 people)

Most common drug interactions over time *:

< 1 month:
  • nausea
  • acute hepatic failure
  • acute respiratory failure
  • anaemia
  • cardiogenic shock
  • chest pain
  • chest x-ray abnormal
  • dyspnoea
  • gastrointestinal haemorrhage
  • gastrooesophageal reflux disease
1 - 6 months:
  • activated partial thromboplastin time prolonged
  • acute respiratory failure
  • asthenia
  • deep vein thrombosis
  • dyspnoea
  • fatigue
  • gastrointestinal haemorrhage
  • haemoglobin decreased
  • multiple injuries
  • myocardial infarction
6 - 12 months:
  • atrial flutter
  • chronic depression
  • chronic fatigue syndrome
  • headache
  • insomnia
  • numbness in hands or feet
  • pain - muscles
  • stress and anxiety
  • gastrointestinal haemorrhage
1 - 2 years:
  • high blood cholesterol
  • high blood sugar
  • gastrointestinal haemorrhage
  • myocardial infarction
  • acute respiratory failure
  • deep vein thrombosis
  • hepatic function abnormal
  • pulmonary embolism
  • pulseless electrical activity
  • blood cholesterol increased
2 - 5 years:
  • arthritis
  • angina unstable
  • arthralgia
  • blood pressure increased
  • chronic fatigue syndrome
  • confusion
  • disorientation
  • diuretic effect
  • eyes - dry
  • frequent or urgent urination
5 - 10 years:
  • gastrointestinal haemorrhage
  • high blood cholesterol
  • high blood pressure
  • arthritis
  • blood pressure increased
  • compulsive shopping
  • contusion
  • diuretic effect
  • fall
  • fibromyalgia
10+ years:
  • high blood cholesterol
  • high blood sugar
  • gastrointestinal haemorrhage
  • low platelet count
  • abdominal pain
  • diarrhoea
  • fatigue
  • frequent or urgent urination
  • haematochezia
  • hot flush
not specified:
  • nausea
  • dyspnoea
  • fatigue
  • diarrhoea
  • fall
  • asthenia
  • pain
  • drug ineffective
  • weight decreased
  • dizziness

Most common drug interactions by gender *:

female:
  • nausea
  • fall
  • dizziness
  • diarrhoea
  • dyspnoea
  • fatigue
  • headache
  • pain
  • pneumonia
  • vomiting
male:
  • dyspnoea
  • asthenia
  • gastrointestinal haemorrhage
  • fatigue
  • weight decreased
  • drug ineffective
  • myocardial infarction
  • dehydration
  • malaise
  • nausea

Most common drug interactions by age *:

0-1:
  • chest pain
  • dizziness
  • haematuria
  • heart rate decreased
  • oral discomfort
  • pruritus generalised
  • rash generalised
  • urticaria
  • vaginal haemorrhage
2-9:
  • abdominal pain
  • anal haemorrhage
  • asthenia
  • blood 1,25-dihydroxycholecalciferol increased
  • blood creatine increased
  • blood iron decreased
  • blood pressure fluctuation
  • dyspnoea
  • epistaxis
  • haemoglobin decreased
10-19:
  • cold intolerance
  • heat syncope
  • injection site pain
20-29:
  • transient ischaemic attack
30-39:
  • thrombosis
  • influenza
  • osteonecrosis of jaw
  • rash
  • renal failure
  • stevens-johnson syndrome
  • swelling face
40-49:
  • diarrhoea
  • alopecia
  • asthenia
  • decreased appetite
  • dizziness
  • fracture
  • nausea
  • nerve compression
  • pneumonia
  • acute myocardial infarction
50-59:
  • nausea
  • anxiety
  • chest pain
  • depression
  • oedema peripheral
  • dyspepsia
  • dyspnoea
  • malaise
  • weight decreased
  • angina unstable
60+:
  • dyspnoea
  • gastrointestinal haemorrhage
  • fall
  • fatigue
  • nausea
  • asthenia
  • diarrhoea
  • pneumonia
  • dizziness
  • anaemia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Vitamin b12 (cobalamin) is often used to treat vitamin supplementation. Plavix (clopidogrel bisulfate) is often used to treat stent. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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