Review: taking Vitamin b12 and Plavix together


Summary

Drug interactions are reported among people who take Vitamin b12 and Plavix together. This review analyzes the effectiveness and drug interactions between Vitamin b12 and Plavix. It is created by eHealthMe based on reports of 244 people who take the same drugs from FDA and social media, and is updated regularly.

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Vitamin B12

Vitamin b12 has active ingredients of cobalamin. It is often used in vitamin supplementation. (latest outcomes from Vitamin b12 7,665 users)

Plavix

Plavix has active ingredients of clopidogrel bisulfate. It is often used in stent. (latest outcomes from Plavix 80,069 users)

On Aug, 26, 2016

244 people who take Vitamin B12, Plavix are studied.


Number of reports submitted per year:

Vitamin b12 and Plavix drug interactions.

Drug effectiveness over time:

Vitamin B12:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 2 people)
  • 2 - 5 years: 16.0% - (1 of 6 people)
  • 5 - 10 years: 100.0% - (5 of 5 people)
  • 10+ years: 25.0% - (1 of 4 people)
  • not specified: 0.0% - (0 of 0 people)
Plavix:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 100.0% - (1 of 1 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 75.0% - (3 of 4 people)
  • 5 - 10 years: 100.0% - (4 of 4 people)
  • 10+ years: 50.0% - (2 of 4 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Vitamin B12:
  • female: 40.0% - (4 of 10 people)
  • male: 37.0% - (3 of 8 people)
Plavix:
  • female: 66.0% - (6 of 9 people)
  • male: 62.0% - (5 of 8 people)

Drug effectiveness by age:

Vitamin B12:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 100.0% - (2 of 2 people)
  • 50-59: 42.0% - (3 of 7 people)
  • 60+: 22.0% - (2 of 9 people)
Plavix:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 100.0% - (5 of 5 people)
  • 60+: 50.0% - (5 of 10 people)

Most common drug interactions over time *:

< 1 month:
  • hepatic function abnormal
  • iron deficiency anaemia
  • nausea
  • arthralgia
  • diarrhoea
  • gastrointestinal haemorrhage
  • headache
  • pancreatitis acute
  • sepsis
  • upper gastrointestinal haemorrhage
1 - 6 months:
  • anaemia
  • arthropathy
  • dermatitis exfoliative
  • frequent or urgent urination
  • po2 increased
  • toxic skin eruption
6 - 12 months:
  • atrial flutter
  • chronic depression
  • chronic fatigue syndrome
  • headache
  • insomnia
  • numbness in hands or feet
  • pain - muscles
  • stress and anxiety
  • gastrointestinal haemorrhage
1 - 2 years:
  • high blood cholesterol
  • high blood sugar
  • hepatic function abnormal
  • pancreatitis acute
  • sepsis
2 - 5 years:
  • angina unstable
  • arthritis
  • blood pressure increased
  • chronic fatigue syndrome
  • confusion
  • disorientation
  • diuretic effect
  • eyes - dry
  • frequent or urgent urination
  • gouty arthritis
5 - 10 years:
  • high blood cholesterol
  • high blood pressure
  • arthritis
  • blood pressure increased
  • compulsive shopping
  • diuretic effect
  • fibromyalgia
  • gastrointestinal haemorrhage
  • gouty arthritis
  • high blood glucose level - infants
10+ years:
  • high blood cholesterol
  • high blood sugar
  • low platelet count
  • abdominal pain
  • diarrhoea
  • fatigue
  • frequent or urgent urination
  • gastrointestinal haemorrhage
  • haematochezia
  • hot flush
not specified:
  • nausea
  • dyspnoea
  • dehydration
  • fatigue
  • dyspepsia
  • anxiety
  • weight decreased
  • depression
  • drug ineffective
  • malaise

Most common drug interactions by gender *:

female:
  • nausea
  • dyspnoea
  • fall
  • fatigue
  • vomiting
  • drug ineffective
  • asthma
  • dyspepsia
  • gastrooesophageal reflux disease
  • hypertension
male:
  • weight decreased
  • dehydration
  • dyspnoea
  • malaise
  • insomnia
  • crohn's disease
  • dyspepsia
  • muscle spasms
  • angina unstable
  • anxiety

Most common drug interactions by age *:

2-9:
  • abdominal pain
  • anal haemorrhage
  • asthenia
  • blood 1,25-dihydroxycholecalciferol increased
  • blood creatine increased
  • blood iron decreased
  • blood pressure fluctuation
  • dyspnoea
  • epistaxis
  • haemoglobin decreased
10-19:
  • cold intolerance
  • heat syncope
  • injection site pain
20-29:
  • transient ischaemic attack
30-39:
  • thrombosis
  • rash
  • renal failure
  • stevens-johnson syndrome
  • swelling face
40-49:
  • agranulocytosis
  • angina pectoris
  • arthralgia
  • blood glucose fluctuation
  • coronary artery occlusion
  • cough
  • depression
  • diabetic ketoacidosis
  • granulocytopenia
  • gynaecomastia
50-59:
  • dyspepsia
  • anxiety
  • depression
  • dyspnoea
  • nausea
  • angina unstable
  • insomnia
  • malaise
  • pyrexia
  • weight decreased
60+:
  • nausea
  • dehydration
  • pneumonia
  • fall
  • fatigue
  • anaemia
  • high blood cholesterol
  • hypertension
  • atrial fibrillation
  • dyspnoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Vitamin b12 (cobalamin) is often used to treat vitamin supplementation. Plavix (clopidogrel bisulfate) is often used to treat stent. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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