Review: taking Vyvanse and Suboxone together


Summary

Drug interactions are reported among people who take Vyvanse and Suboxone together. This review analyzes the effectiveness and drug interactions between Vyvanse and Suboxone. It is created by eHealthMe based on reports of 67 people who take the same drugs from FDA and social media, and is updated regularly.

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Vyvanse

Vyvanse has active ingredients of lisdexamfetamine dimesylate. It is often used in attention deficit hyperactivity disorder. (latest outcomes from Vyvanse 7,909 users)

Suboxone

Suboxone has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is often used in drug dependence. (latest outcomes from Suboxone 8,195 users)

On Jul, 27, 2016

67 people who take Vyvanse, Suboxone are studied.


Number of reports submitted per year:

Vyvanse and Suboxone drug interactions.

Drug effectiveness over time:

Vyvanse:
  • < 1 month: 27.0% - (3 of 11 people)
  • 1 - 6 months: 50.0% - (8 of 16 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 33.0% - (1 of 3 people)
  • 2 - 5 years: 100.0% - (7 of 7 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 2 people)
Suboxone:
  • < 1 month: 40.0% - (2 of 5 people)
  • 1 - 6 months: 100.0% - (8 of 8 people)
  • 6 - 12 months: 100.0% - (11 of 11 people)
  • 1 - 2 years: 66.0% - (4 of 6 people)
  • 2 - 5 years: 100.0% - (9 of 9 people)
  • 5 - 10 years: 100.0% - (2 of 2 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 100.0% - (2 of 2 people)

Drug effectiveness by gender:

Vyvanse:
  • female: 48.0% - (14 of 29 people)
  • male: 58.0% - (7 of 12 people)
Suboxone:
  • female: 90.0% - (29 of 32 people)
  • male: 81.0% - (9 of 11 people)

Drug effectiveness by age:

Vyvanse:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 46.0% - (6 of 13 people)
  • 30-39: 45.0% - (10 of 22 people)
  • 40-49: 75.0% - (3 of 4 people)
  • 50-59: 100.0% - (2 of 2 people)
  • 60+: 0.0% - (0 of 0 people)
Suboxone:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 85.0% - (12 of 14 people)
  • 30-39: 95.0% - (23 of 24 people)
  • 40-49: 33.0% - (1 of 3 people)
  • 50-59: 100.0% - (2 of 2 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • apathy
  • bone loss
  • drug ineffective
  • erythema multiforme
  • sedation
  • somnolence
1 - 6 months:
  • aches and pains in bones
  • belching
  • headache
  • fever
  • gastrointestinal pain
  • bone loss
  • bruxism
  • confusion
  • erythema multiforme
  • euphoric mood
6 - 12 months:
  • appetite decreased
  • constipation
  • sweating - excessive
  • confusion
  • fatigue - chronic
  • hair texture abnormal
  • heart rate increased
  • infection - hair follicle
  • mite bite
  • pinworms
1 - 2 years:
  • gastrointestinal pain
  • bruxism
  • decreased eye contact
  • euphoric mood
  • exacerbation of anxiety
  • impulsive behaviour
  • inappropriate affect
  • insomnia exacerbated
  • obsessive-compulsive disorder
  • pinworms
2 - 5 years:
  • appetite decreased
  • constipation
  • fever
  • sweating - excessive
  • heart rate increased
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • aches and pains in bones
  • belching
  • headache
5 - 10 years:
  • decreased eye contact
  • impulsive behaviour
  • inappropriate affect
  • obsessive-compulsive disorder
  • polydipsia
  • psychotic disorder
not specified:
  • somnolence
  • aggression
  • asthenia
  • asthma
  • constipation
  • disturbance in attention
  • drug intolerance
  • dyspnoea
  • feeling abnormal
  • gait disturbance

Most common drug interactions by gender *:

female:
  • obsessive-compulsive disorder
  • aches and pains in bones
  • asthenia
  • asthma
  • belching
  • constipation
  • disturbance in attention
  • dyspnoea
  • feeling abnormal
  • gait disturbance
male:
  • aggression
  • drug intolerance
  • impaired driving ability
  • intentional overdose
  • mania
  • appetite decreased
  • constipation
  • gastrointestinal pain
  • sweating - excessive
  • abdominal pain upper

Most common drug interactions by age *:

20-29:
  • aggression
  • drug intolerance
  • impaired driving ability
  • intentional overdose
  • mania
  • constipation
  • gastrointestinal pain
  • abdominal pain upper
  • anorexia
  • bone loss
30-39:
  • aches and pains in bones
  • belching
  • headache
  • appetite decreased
  • fever
  • sweating - excessive
  • back disorder
  • drug screen false positive
40-49:
  • depression
  • drug effect decreased
  • drug effect increased
  • insomnia
  • irritability
  • lethargy
  • logorrhoea
  • obsessive-compulsive disorder
  • blister
  • drug withdrawal syndrome
50-59:
  • asthenia
  • asthma
  • constipation
  • disturbance in attention
  • dyspnoea
  • feeling abnormal
  • hallucination
  • oedema peripheral
  • periorbital oedema
  • somnolence

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Vyvanse (lisdexamfetamine dimesylate) is often used to treat attention deficit hyperactivity disorder. Suboxone (buprenorphine hydrochloride; naloxone hydrochloride) is often used to treat drug dependence. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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