Review: taking Vyvanse and Suboxone together


Summary

Drug interactions are reported among people who take Vyvanse and Suboxone together. This review analyzes the effectiveness and drug interactions between Vyvanse and Suboxone. It is created by eHealthMe based on reports of 73 people who take the same drugs from FDA and social media, and is updated regularly.

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Vyvanse

Vyvanse has active ingredients of lisdexamfetamine dimesylate. It is often used in attention deficit hyperactivity disorder. (latest outcomes from Vyvanse 8,869 users)

Suboxone

Suboxone has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is often used in drug dependence. (latest outcomes from Suboxone 10,832 users)

On Aug, 25, 2016

73 people who take Vyvanse, Suboxone are studied.


Number of reports submitted per year:

Vyvanse and Suboxone drug interactions.

Drug effectiveness over time:

Vyvanse:
  • < 1 month: 37.0% - (3 of 8 people)
  • 1 - 6 months: 46.0% - (6 of 13 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 33.0% - (1 of 3 people)
  • 2 - 5 years: 100.0% - (4 of 4 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 1 people)
Suboxone:
  • < 1 month: 40.0% - (2 of 5 people)
  • 1 - 6 months: 100.0% - (5 of 5 people)
  • 6 - 12 months: 100.0% - (8 of 8 people)
  • 1 - 2 years: 50.0% - (2 of 4 people)
  • 2 - 5 years: 100.0% - (6 of 6 people)
  • 5 - 10 years: 100.0% - (2 of 2 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Vyvanse:
  • female: 52.0% - (11 of 21 people)
  • male: 50.0% - (5 of 10 people)
Suboxone:
  • female: 86.0% - (19 of 22 people)
  • male: 77.0% - (7 of 9 people)

Drug effectiveness by age:

Vyvanse:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 45.0% - (5 of 11 people)
  • 30-39: 46.0% - (7 of 15 people)
  • 40-49: 75.0% - (3 of 4 people)
  • 50-59: 100.0% - (1 of 1 people)
  • 60+: 0.0% - (0 of 0 people)
Suboxone:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 83.0% - (10 of 12 people)
  • 30-39: 93.0% - (14 of 15 people)
  • 40-49: 33.0% - (1 of 3 people)
  • 50-59: 100.0% - (1 of 1 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • bronchitis
  • chills
  • hot flush
  • hyperhidrosis
  • hypoacusis
  • nausea
  • neuralgia
  • pain
  • polychondritis
  • therapeutic response unexpected
1 - 6 months:
  • aches and pains in bones
  • belching
  • headache
  • fever
  • gastrointestinal pain
  • abortion spontaneous
  • bone loss
  • bruxism
  • confusion
  • drug withdrawal syndrome neonatal
6 - 12 months:
  • appetite decreased
  • constipation
  • sweating - excessive
  • confusion
  • fatigue - chronic
  • hair texture abnormal
  • heart rate increased
  • infection - hair follicle
  • mite bite
  • pinworms
1 - 2 years:
  • gastrointestinal pain
  • abnormal sleep-related event
  • abortion spontaneous
  • bronchitis
  • bruxism
  • chills
  • decreased eye contact
  • euphoric mood
  • exacerbation of anxiety
  • gastrooesophageal reflux disease
2 - 5 years:
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • aches and pains in bones
  • belching
  • headache
  • appetite decreased
  • constipation
  • fever
  • sweating - excessive
  • heart rate increased
5 - 10 years:
  • abnormal sleep-related event
  • decreased eye contact
  • gastrooesophageal reflux disease
  • hiatus hernia
  • impaired gastric emptying
  • impulsive behaviour
  • inappropriate affect
  • obsessive-compulsive disorder
  • polydipsia
  • psychotic disorder
not specified:
  • feeling abnormal
  • depression
  • drug effect decreased
  • drug effect increased
  • insomnia
  • irritability
  • lethargy
  • logorrhoea
  • obsessive-compulsive disorder
  • somnolence

Most common drug interactions by gender *:

female:
  • hot flush
  • nausea
  • obsessive-compulsive disorder
  • feeling abnormal
  • bronchitis
  • chills
  • depression
  • drug effect decreased
  • drug effect increased
  • hyperhidrosis
male:
  • aggression
  • drug intolerance
  • impaired driving ability
  • intentional overdose
  • mania
  • appetite decreased
  • constipation
  • gastrointestinal pain
  • sweating - excessive
  • abdominal pain upper

Most common drug interactions by age *:

20-29:
  • aggression
  • drug intolerance
  • impaired driving ability
  • intentional overdose
  • mania
  • constipation
  • gastrointestinal pain
  • abdominal pain upper
  • abnormal sleep-related event
  • anorexia
30-39:
  • hot flush
  • nausea
  • bronchitis
  • chills
  • hyperhidrosis
  • hypoacusis
  • neuralgia
  • pain
  • polychondritis
  • therapeutic response unexpected
40-49:
  • depression
  • drug effect decreased
  • drug effect increased
  • insomnia
  • irritability
  • lethargy
  • logorrhoea
  • obsessive-compulsive disorder
  • blister
  • drug withdrawal syndrome
50-59:
  • asthenia
  • asthma
  • constipation
  • disturbance in attention
  • dyspnoea
  • feeling abnormal
  • hallucination
  • oedema peripheral
  • periorbital oedema
  • somnolence

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Vyvanse (lisdexamfetamine dimesylate) is often used to treat attention deficit hyperactivity disorder. Suboxone (buprenorphine hydrochloride; naloxone hydrochloride) is often used to treat drug dependence. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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