Review: taking Warfarin sodium and Celebrex together


Summary

Drug interactions are reported among people who take Warfarin sodium and Celebrex together. This review analyzes the effectiveness and drug interactions between Warfarin sodium and Celebrex. It is created by eHealthMe based on reports of 3,736 people who take the same drugs from FDA and social media, and is updated regularly.

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Warfarin Sodium

Warfarin sodium has active ingredients of warfarin sodium. It is often used in atrial fibrillation/flutter. (latest outcomes from Warfarin sodium 48,044 users)

Celebrex

Celebrex has active ingredients of celecoxib. It is often used in arthritis. (latest outcomes from Celebrex 73,555 users)

On Jul, 22, 2016

3,736 people who take Warfarin Sodium, Celebrex are studied.


Number of reports submitted per year:

Warfarin sodium and Celebrex drug interactions.

Drug effectiveness over time:

Warfarin Sodium:
  • < 1 month: 33.0% - (1 of 3 people)
  • 1 - 6 months: 60.0% - (3 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 2 people)
  • 1 - 2 years: 75.0% - (3 of 4 people)
  • 2 - 5 years: 80.0% - (4 of 5 people)
  • 5 - 10 years: 100.0% - (11 of 11 people)
  • 10+ years: 100.0% - (11 of 11 people)
  • not specified: 0.0% - (0 of 0 people)
Celebrex:
  • < 1 month: 50.0% - (2 of 4 people)
  • 1 - 6 months: 66.0% - (6 of 9 people)
  • 6 - 12 months: 0.0% - (0 of 2 people)
  • 1 - 2 years: 20.0% - (1 of 5 people)
  • 2 - 5 years: 43.0% - (7 of 16 people)
  • 5 - 10 years: 20.0% - (1 of 5 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Warfarin Sodium:
  • female: 73.0% - (17 of 23 people)
  • male: 88.0% - (16 of 18 people)
Celebrex:
  • female: 56.0% - (14 of 25 people)
  • male: 17.0% - (3 of 17 people)

Drug effectiveness by age:

Warfarin Sodium:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 75.0% - (3 of 4 people)
  • 40-49: 100.0% - (2 of 2 people)
  • 50-59: 81.0% - (13 of 16 people)
  • 60+: 78.0% - (15 of 19 people)
Celebrex:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 75.0% - (3 of 4 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 25.0% - (4 of 16 people)
  • 60+: 45.0% - (9 of 20 people)

Most common drug interactions over time *:

< 1 month:
  • haemorrhage
  • atrial fibrillation
  • pneumonia
  • cerebrovascular accident
  • arrhythmia
  • myocardial infarction
  • cardiac failure congestive
  • dyspnoea
  • international normalised ratio increased
  • peripheral ischaemia
1 - 6 months:
  • cerebrovascular accident
  • anxiety
  • death
  • chest pain
  • dizziness
  • fall
  • nausea
  • neutropenia
  • thrombocytopenia
  • anhedonia
6 - 12 months:
  • lower gastrointestinal haemorrhage
  • deep vein thrombosis
  • emotional distress
  • injury
  • myocardial infarction
  • pain
  • asthenia
  • atrial fibrillation
  • electrocardiogram qt prolonged
  • gastric ulcer
1 - 2 years:
  • myocardial infarction
  • chest pain
  • dyspnoea
  • cerebrovascular accident
  • dizziness
  • gout
  • international normalised ratio increased
  • back pain
  • blood cholesterol increased
  • fall
2 - 5 years:
  • depression
  • dizziness
  • tremor
  • cerebrovascular accident
  • cognitive deterioration
  • fatigue - chronic
  • gait abnormal
  • hyperacusis
  • hyporeflexia
  • loss of sensation, numbness and tingling, paresthesias, sensory loss, tingling and numbness
5 - 10 years:
  • depression
  • cognitive deterioration
  • dizziness
  • fatigue - chronic
  • gait abnormal
  • hyperacusis
  • hyporeflexia
  • loss of sensation, numbness and tingling, paresthesias, sensory loss, tingling and numbness
  • muscle twitching
  • myelomalacia
10+ years:
  • cardiac disorder
  • haematoma
  • international normalised ratio increased
  • abdominal pain upper
  • coagulopathy
  • drug level increased
  • haemoglobin decreased
  • haemorrhage
  • hypotension
  • international normalised ratio decreased
not specified:
  • pain
  • anxiety
  • osteonecrosis of jaw
  • dyspnoea
  • anaemia
  • injury
  • fatigue
  • nausea
  • back pain
  • osteoarthritis

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • osteonecrosis of jaw
  • fall
  • anaemia
  • osteoarthritis
  • nausea
  • dyspnoea
  • injury
  • arthralgia
male:
  • pain
  • anxiety
  • dyspnoea
  • pneumonia
  • injury
  • osteonecrosis of jaw
  • fatigue
  • anaemia
  • back pain
  • atrial fibrillation

Most common drug interactions by age *:

0-1:
  • arthralgia
  • blood lactate dehydrogenase increased
  • hepatic cancer metastatic
  • myalgia
  • oedema peripheral
  • urine colour abnormal
2-9:
  • disease recurrence
  • drug ineffective
  • herpes zoster
  • mucosal inflammation
  • oesophagitis
10-19:
  • chest pain
  • drug effect decreased
  • oedema peripheral
  • pulmonary embolism
20-29:
  • chest pain
  • dyspnoea
  • pulmonary embolism
  • abdominal pain
  • paraesthesia
  • cerebrovascular accident
  • dizziness
  • international normalised ratio increased
  • angioedema
  • burning sensation
30-39:
  • injury
  • pain
  • anxiety
  • pain in extremity
  • abdominal distension
  • feeling abnormal
  • international normalised ratio increased
  • haematuria
  • pleural fibrosis
  • splenomegaly
40-49:
  • pain
  • bone disorder
  • abdominal pain
  • osteomyelitis
  • pain in extremity
  • deep vein thrombosis
  • oedema peripheral
  • osteonecrosis of jaw
  • osteoarthritis
  • primary sequestrum
50-59:
  • pain
  • anxiety
  • osteonecrosis of jaw
  • nausea
  • anaemia
  • depression
  • fatigue
  • bone lesion
  • pleural effusion
  • infection
60+:
  • pain
  • anxiety
  • anaemia
  • fall
  • dyspnoea
  • injury
  • atrial fibrillation
  • international normalised ratio increased
  • asthenia
  • fatigue

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Warfarin sodium (warfarin sodium) is often used to treat atrial fibrillation/flutter. Celebrex (celecoxib) is often used to treat arthritis. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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