Review: taking Warfarin sodium and Clonazepam together


Summary

Drug interactions are reported among people who take Warfarin sodium and Clonazepam together. This review analyzes the effectiveness and drug interactions between Warfarin sodium and Clonazepam. It is created by eHealthMe based on reports of 2,405 people who take the same drugs from FDA and social media, and is updated regularly.

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Warfarin Sodium

Warfarin sodium has active ingredients of warfarin sodium. It is often used in atrial fibrillation/flutter. (latest outcomes from Warfarin sodium 49,826 users)

Clonazepam

Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from Clonazepam 45,597 users)

On Aug, 24, 2016

2,405 people who take Warfarin Sodium, Clonazepam are studied.


Number of reports submitted per year:

Warfarin sodium and Clonazepam drug interactions.

Drug effectiveness over time:

Warfarin Sodium:
  • < 1 month: 25.0% - (1 of 4 people)
  • 1 - 6 months: 25.0% - (3 of 12 people)
  • 6 - 12 months: 80.0% - (4 of 5 people)
  • 1 - 2 years: 50.0% - (4 of 8 people)
  • 2 - 5 years: 44.0% - (4 of 9 people)
  • 5 - 10 years: 80.0% - (4 of 5 people)
  • 10+ years: 66.0% - (4 of 6 people)
  • not specified: 0.0% - (0 of 0 people)
Clonazepam:
  • < 1 month: 25.0% - (1 of 4 people)
  • 1 - 6 months: 11.0% - (1 of 9 people)
  • 6 - 12 months: 50.0% - (2 of 4 people)
  • 1 - 2 years: 42.0% - (3 of 7 people)
  • 2 - 5 years: 41.0% - (5 of 12 people)
  • 5 - 10 years: 42.0% - (3 of 7 people)
  • 10+ years: 42.0% - (3 of 7 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Warfarin Sodium:
  • female: 48.0% - (13 of 27 people)
  • male: 50.0% - (11 of 22 people)
Clonazepam:
  • female: 39.0% - (11 of 28 people)
  • male: 31.0% - (7 of 22 people)

Drug effectiveness by age:

Warfarin Sodium:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 33.0% - (2 of 6 people)
  • 40-49: 50.0% - (5 of 10 people)
  • 50-59: 60.0% - (6 of 10 people)
  • 60+: 50.0% - (11 of 22 people)
Clonazepam:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 33.0% - (2 of 6 people)
  • 40-49: 45.0% - (5 of 11 people)
  • 50-59: 33.0% - (3 of 9 people)
  • 60+: 34.0% - (8 of 23 people)

Most common drug interactions over time *:

< 1 month:
  • international normalised ratio increased
  • anxiety
  • depression
  • pain
  • fall
  • headache
  • international normalised ratio decreased
  • nausea
  • anal cancer
  • aplasia pure red cell
1 - 6 months:
  • cardiac failure congestive
  • haemorrhage
  • malaise
  • nausea
  • international normalised ratio increased
  • pain
  • cough
  • fatigue
  • gastrointestinal haemorrhage
  • gastrooesophageal reflux disease
6 - 12 months:
  • petechiae
  • transient ischaemic attack
  • depression
  • thrombosis
  • balance disorder
  • bleeding time shortened
  • blood creatine phosphokinase increased
  • cardiac arrest
  • cerebrovascular accident
  • chills
1 - 2 years:
  • depression
  • emotional distress
  • hypersexuality
  • obsessive-compulsive personality disorder
  • pathological gambling
  • suicidal ideation
  • cholecystitis acute
  • haematoma
  • pneumonia
  • septic shock
2 - 5 years:
  • dental caries
  • drooling
  • enamel anomaly
  • oral pain
  • tooth extraction
  • tooth fracture
  • toothache
  • diarrhoea
  • tooth loss
  • anxiety
5 - 10 years:
  • headache
  • suicidal ideation
  • confusional state
  • bradykinesia
  • bradyphrenia
  • hysterectomy
  • nephrogenic systemic fibrosis
  • anhedonia
  • anxiety
  • emotional distress
10+ years:
  • transient ischaemic attack
  • depression
  • skin blushing/flushing
  • abdominal pain
  • anhedonia
  • anxiety
  • anxiety and stress
  • anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension
  • asthma late onset
  • atrial fibrillation aggravated
not specified:
  • pain
  • anxiety
  • dyspnoea
  • fatigue
  • fall
  • nausea
  • depression
  • back pain
  • pneumonia
  • oedema peripheral

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • dyspnoea
  • fatigue
  • nausea
  • depression
  • fall
  • headache
  • arthralgia
  • back pain
male:
  • pain
  • anxiety
  • fall
  • dyspnoea
  • fatigue
  • atrial fibrillation
  • anaemia
  • nausea
  • depression
  • oedema peripheral

Most common drug interactions by age *:

0-1:
  • deep vein thrombosis
  • neuroleptic malignant syndrome
  • pulmonary embolism
  • suicide attempt
  • systemic lupus erythematosus
  • type 2 diabetes mellitus
2-9:
  • suicide attempt
  • irritability
  • cardiovascular disorder
  • electrolyte imbalance
  • intentional overdose
  • mental disorder
  • clostridium difficile colitis
  • withdrawal syndrome
  • anxiety
  • balance disorder
10-19:
  • anaemia
  • anxiety
  • arthralgia
  • back pain
  • bronchitis
  • contusion
  • cough
  • dyspnoea
  • gastrooesophageal reflux disease
  • hiatus hernia
20-29:
  • fatigue
  • insomnia
  • cardiac failure congestive
  • pain
  • bronchitis
  • influenza like illness
  • sinusitis
  • urinary tract infection
  • cholecystitis
  • fall
30-39:
  • nausea
  • pain
  • anxiety
  • headache
  • neuroleptic malignant syndrome
  • dyspnoea
  • asthenia
  • back pain
  • circulatory collapse
  • hypoaesthesia
40-49:
  • fatigue
  • pain
  • weight decreased
  • anxiety
  • dyspnoea
  • pneumonia
  • headache
  • suicidal ideation
  • deep vein thrombosis
  • gastrooesophageal reflux disease
50-59:
  • pain
  • anxiety
  • depression
  • fatigue
  • fall
  • dyspnoea
  • pyrexia
  • osteonecrosis of jaw
  • osteomyelitis
  • arthralgia
60+:
  • pain
  • fall
  • nausea
  • atrial fibrillation
  • anxiety
  • dyspnoea
  • international normalised ratio increased
  • oedema peripheral
  • cardiac failure congestive
  • depression

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Warfarin sodium (warfarin sodium) is often used to treat atrial fibrillation/flutter. Clonazepam (clonazepam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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