Review: taking Wellbutrin xl and Bontril together


Summary

Drug interactions are reported among people who take Wellbutrin xl and Bontril together. This review analyzes the effectiveness and drug interactions between Wellbutrin xl and Bontril. It is created by eHealthMe based on reports of 41 people who take the same drugs from FDA and social media, and is updated regularly.

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Wellbutrin Xl

Wellbutrin xl has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from Wellbutrin xl 13,949 users)

Bontril

Bontril has active ingredients of phendimetrazine tartrate. It is often used in weight loss. (latest outcomes from Bontril 133 users)

On Aug, 26, 2016

41 people who take Wellbutrin Xl, Bontril are studied.


Number of reports submitted per year:

Wellbutrin xl and Bontril drug interactions.

Drug effectiveness over time:

Wellbutrin Xl:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 100.0% - (2 of 2 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Bontril:
  • < 1 month: 66.0% - (2 of 3 people)
  • 1 - 6 months: 50.0% - (1 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Wellbutrin Xl:
  • female: 33.0% - (2 of 6 people)
  • male: 100.0% - (1 of 1 people)
Bontril:
  • female: 40.0% - (2 of 5 people)
  • male: 100.0% - (1 of 1 people)

Drug effectiveness by age:

Wellbutrin Xl:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 33.0% - (1 of 3 people)
  • 40-49: 66.0% - (2 of 3 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 0.0% - (0 of 0 people)
Bontril:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 50.0% - (1 of 2 people)
  • 40-49: 66.0% - (2 of 3 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • completed suicide
  • constipation
  • decreased appetite
  • depression
  • gastric ulcer
  • abdominal distension
  • aggression
  • agitated depression
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
1 - 6 months:
  • weight gain
6 - 12 months:
  • heat cramps
1 - 2 years:
  • weight gain
not specified:
  • fatigue
  • decreased appetite
  • depression
  • insomnia
  • abdominal distension
  • abdominal pain
  • blood potassium decreased
  • chest pain
  • constipation
  • convulsion

Most common drug interactions by gender *:

female:
  • weight gain
  • fatigue
  • blood potassium decreased
  • chest pain
  • convulsion
  • depression
  • diarrhoea
  • dysarthria
  • excessive skin
  • headache
male:
  • gastric ulcer
  • decreased appetite
  • depression
  • abdominal distension
  • aggression
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • completed suicide
  • constipation
  • hallucination

Most common drug interactions by age *:

10-19:
  • anal fissure
  • blood cholesterol increased
  • blood glucose increased
  • blood triglycerides increased
  • colitis ulcerative
  • crohn's disease
  • depression
  • inflammatory bowel disease
20-29:
  • fatigue
  • blood potassium decreased
  • chest pain
  • convulsion
  • dysarthria
  • heart rate irregular
  • hypertension
  • malaise
  • nasopharyngitis
  • pyrexia
30-39:
  • agitated depression
  • depression
  • depression suicidal
  • inability to sleep
  • increased tendency to bruise
  • migraine
  • mood swings
  • nausea
  • red blood cell count decreased
40-49:
  • weight gain
  • dysgeusia
  • heat cramps
50-59:
  • gastric ulcer
  • abdominal distension
  • aggression
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • completed suicide
  • constipation
  • decreased appetite
  • depression
  • excessive skin
60+:
  • injection site pain
  • oropharyngeal pain
  • paraesthesia
  • weight decreased

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Wellbutrin xl (bupropion hydrochloride) is often used to treat depression. Bontril (phendimetrazine tartrate) is often used to treat weight loss. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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