Review: taking Wellbutrin and Aleve together


Summary

Drug interactions are reported among people who take Wellbutrin and Aleve together. This review analyzes the effectiveness and drug interactions between Wellbutrin and Aleve. It is created by eHealthMe based on reports of 1,664 people who take the same drugs from FDA and social media, and is updated regularly.

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Wellbutrin

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from Wellbutrin 58,718 users)

Aleve

Aleve has active ingredients of naproxen sodium. It is often used in arthritis. (latest outcomes from Aleve 23,811 users)

On Aug, 18, 2016

1,664 people who take Wellbutrin, Aleve are studied.


Number of reports submitted per year:

Wellbutrin and Aleve drug interactions.

Drug effectiveness over time:

Wellbutrin:
  • < 1 month: 28.0% - (4 of 14 people)
  • 1 - 6 months: 25.0% - (6 of 24 people)
  • 6 - 12 months: 33.0% - (2 of 6 people)
  • 1 - 2 years: 28.0% - (4 of 14 people)
  • 2 - 5 years: 47.0% - (11 of 23 people)
  • 5 - 10 years: 75.0% - (9 of 12 people)
  • 10+ years: 64.0% - (9 of 14 people)
  • not specified: 50.0% - (1 of 2 people)
Aleve:
  • < 1 month: 20.0% - (5 of 24 people)
  • 1 - 6 months: 12.0% - (3 of 24 people)
  • 6 - 12 months: 33.0% - (2 of 6 people)
  • 1 - 2 years: 25.0% - (3 of 12 people)
  • 2 - 5 years: 35.0% - (5 of 14 people)
  • 5 - 10 years: 61.0% - (8 of 13 people)
  • 10+ years: 62.0% - (5 of 8 people)
  • not specified: 50.0% - (1 of 2 people)

Drug effectiveness by gender:

Wellbutrin:
  • female: 43.0% - (39 of 89 people)
  • male: 35.0% - (7 of 20 people)
Aleve:
  • female: 27.0% - (23 of 83 people)
  • male: 45.0% - (9 of 20 people)

Drug effectiveness by age:

Wellbutrin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 42.0% - (6 of 14 people)
  • 30-39: 36.0% - (11 of 30 people)
  • 40-49: 51.0% - (14 of 27 people)
  • 50-59: 38.0% - (10 of 26 people)
  • 60+: 36.0% - (4 of 11 people)
Aleve:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 30.0% - (4 of 13 people)
  • 30-39: 25.0% - (7 of 27 people)
  • 40-49: 32.0% - (9 of 28 people)
  • 50-59: 32.0% - (8 of 25 people)
  • 60+: 40.0% - (4 of 10 people)

Most common drug interactions over time *:

< 1 month:
  • dizziness
  • anxiety
  • pain
  • suicide attempt
  • weakness
  • anger
  • nervousness
  • arthralgia
  • insomnia
  • suicidal ideation
1 - 6 months:
  • abdominal pain diagnosis
  • burning feet syndrome
  • dizziness
  • ibs
  • joint instability
  • loss of sensation, numbness and tingling, paresthesias, sensory loss, tingling and numbness
  • muscle aches
  • skin discoloration - bluish
  • migraine
  • nausea
6 - 12 months:
  • abdominal pain upper
  • cholelithiasis
  • asthenia
  • cholecystitis
  • nausea
  • pancreatitis
  • pyrexia
  • vomiting
  • diabetes mellitus
  • fatigue
1 - 2 years:
  • dizziness
  • anger
  • confusion
  • frustration
  • nervousness
  • vision blurred
  • weakness
  • dark circles under eyes
  • insomnia related to another mental condition
  • movement - uncoordinated
2 - 5 years:
  • pain
  • diverticulitis
  • pulmonary embolism
  • type 2 diabetes mellitus
  • diabetes mellitus
  • anxiety
  • loss of libido
  • altered state of consciousness
  • cholecystitis acute
  • chronic fatigue syndrome
5 - 10 years:
  • depression
  • anxiety
  • vision blurred
  • abdominal pain diagnosis
  • burning feet syndrome
  • ibs
  • joint instability
  • loss of sensation, numbness and tingling, paresthesias, sensory loss, tingling and numbness
  • muscle aches
  • pain - muscles
10+ years:
  • numbness and tingling
  • altered visual depth perception
  • anxiety
  • aphasia
  • depression
  • fatigue
  • irritability
  • suicidal thoughts
  • tinnitus
  • vertigo
not specified:
  • pain
  • anxiety
  • depression
  • back pain
  • dyspnoea
  • nausea
  • fatigue
  • injury
  • fall
  • arthralgia

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • depression
  • back pain
  • fall
  • fatigue
  • nausea
  • injury
  • anaemia
  • pain in extremity
male:
  • anxiety
  • pain
  • dyspnoea
  • depression
  • nausea
  • dizziness
  • vomiting
  • chronic obstructive pulmonary disease
  • diabetes mellitus
  • back pain

Most common drug interactions by age *:

2-9:
  • joint swelling
  • malaise
  • pericardial effusion
  • photophobia
  • pleural effusion
  • pyrexia
  • abasia
  • anaemia
  • anorexia
  • arthralgia
10-19:
  • cholecystitis
  • cholecystitis chronic
  • gallbladder cholesterolosis
  • gallbladder disorder
  • emotional distress
  • pain
  • anxiety
  • general physical health deterioration
  • injury
  • pulmonary embolism
20-29:
  • pain
  • pulmonary embolism
  • cholelithiasis
  • injury
  • deep vein thrombosis
  • cholecystitis chronic
  • anxiety
  • emotional distress
  • gallbladder disorder
  • diabetes mellitus
30-39:
  • diabetes mellitus
  • cholelithiasis
  • nausea
  • dyspnoea
  • type 2 diabetes mellitus
  • abdominal pain upper
  • cholecystitis chronic
  • completed suicide
  • fatigue
  • deep vein thrombosis
40-49:
  • anxiety
  • pain
  • depression
  • diabetes mellitus
  • chest pain
  • dizziness
  • fatigue
  • emotional distress
  • fall
  • back pain
50-59:
  • osteoarthritis
  • back pain
  • dyspnoea
  • pain
  • pain in extremity
  • anxiety
  • anaemia
  • constipation
  • paraesthesia
  • nausea
60+:
  • weight decreased
  • vomiting
  • nausea
  • fatigue
  • diarrhoea
  • fall
  • depression
  • dyspnoea
  • anxiety
  • dizziness

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Wellbutrin (bupropion hydrochloride) is often used to treat depression. Aleve (naproxen sodium) is often used to treat arthritis. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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