Review: taking Wellbutrin and Aleve together


Summary

Drug interactions are reported among people who take Wellbutrin and Aleve together. This review analyzes the effectiveness and drug interactions between Wellbutrin and Aleve. It is created by eHealthMe based on reports of 2,200 people who take the same drugs from FDA and social media, and is updated regularly.

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Wellbutrin

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from Wellbutrin 69,048 users)

Aleve

Aleve has active ingredients of naproxen sodium. It is often used in arthritis. (latest outcomes from Aleve 37,838 users)

On Sep, 16, 2016

2,200 people who take Wellbutrin, Aleve are studied.


Number of reports submitted per year:

Wellbutrin and Aleve drug interactions.

Drug effectiveness over time:

Wellbutrin:
  • < 1 month: 28.0% - (4 of 14 people)
  • 1 - 6 months: 25.0% - (6 of 24 people)
  • 6 - 12 months: 33.0% - (2 of 6 people)
  • 1 - 2 years: 28.0% - (4 of 14 people)
  • 2 - 5 years: 47.0% - (11 of 23 people)
  • 5 - 10 years: 75.0% - (9 of 12 people)
  • 10+ years: 64.0% - (9 of 14 people)
  • not specified: 50.0% - (1 of 2 people)
Aleve:
  • < 1 month: 21.0% - (5 of 23 people)
  • 1 - 6 months: 12.0% - (3 of 24 people)
  • 6 - 12 months: 33.0% - (2 of 6 people)
  • 1 - 2 years: 25.0% - (3 of 12 people)
  • 2 - 5 years: 35.0% - (5 of 14 people)
  • 5 - 10 years: 61.0% - (8 of 13 people)
  • 10+ years: 62.0% - (5 of 8 people)
  • not specified: 50.0% - (1 of 2 people)

Drug effectiveness by gender:

Wellbutrin:
  • female: 43.0% - (39 of 89 people)
  • male: 35.0% - (7 of 20 people)
Aleve:
  • female: 28.0% - (23 of 82 people)
  • male: 45.0% - (9 of 20 people)

Drug effectiveness by age:

Wellbutrin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 42.0% - (6 of 14 people)
  • 30-39: 36.0% - (11 of 30 people)
  • 40-49: 51.0% - (14 of 27 people)
  • 50-59: 38.0% - (10 of 26 people)
  • 60+: 36.0% - (4 of 11 people)
Aleve:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 30.0% - (4 of 13 people)
  • 30-39: 25.0% - (7 of 27 people)
  • 40-49: 33.0% - (9 of 27 people)
  • 50-59: 32.0% - (8 of 25 people)
  • 60+: 40.0% - (4 of 10 people)

Most common drug interactions over time *:

< 1 month:
  • dizziness
  • diarrhoea
  • nausea
  • loss of consciousness
  • anxiety
  • pain
  • suicide attempt
  • paraesthesia
  • weakness
  • anger
1 - 6 months:
  • abdominal pain diagnosis
  • burning feet syndrome
  • dizziness
  • ibs
  • joint instability
  • loss of sensation, numbness and tingling, paresthesias, sensory loss, tingling and numbness
  • muscle aches
  • skin discoloration - bluish
  • insomnia
  • migraine
6 - 12 months:
  • abdominal pain upper
  • cholelithiasis
  • asthenia
  • cholecystitis
  • nausea
  • pancreatitis
  • pyrexia
  • vomiting
  • diabetes mellitus
  • fatigue
1 - 2 years:
  • dizziness
  • vision blurred
  • anger
  • confusion
  • frustration
  • nervousness
  • pain in extremity
  • weakness
  • insomnia
  • nausea
2 - 5 years:
  • pain
  • diverticulitis
  • pulmonary embolism
  • type 2 diabetes mellitus
  • diabetes mellitus
  • anxiety
  • loss of libido
  • altered state of consciousness
  • cholecystitis acute
  • chronic fatigue syndrome
5 - 10 years:
  • depression
  • vision blurred
  • anxiety
  • abdominal pain diagnosis
  • burning feet syndrome
  • ibs
  • joint instability
  • loss of sensation, numbness and tingling, paresthesias, sensory loss, tingling and numbness
  • muscle aches
  • pain - muscles
10+ years:
  • anxiety
  • numbness and tingling
  • altered visual depth perception
  • aphasia
  • depression
  • fatigue
  • irritability
  • suicidal thoughts
  • tinnitus
  • vertigo
not specified:
  • pain
  • anxiety
  • depression
  • fatigue
  • nausea
  • back pain
  • fall
  • dyspnoea
  • arthralgia
  • dizziness

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • depression
  • fatigue
  • fall
  • back pain
  • nausea
  • pain in extremity
  • arthralgia
  • dyspnoea
male:
  • anxiety
  • pain
  • depression
  • dyspnoea
  • dizziness
  • nausea
  • fatigue
  • vomiting
  • headache
  • back pain

Most common drug interactions by age *:

2-9:
  • joint swelling
  • malaise
  • pericardial effusion
  • photophobia
  • pleural effusion
  • pyrexia
  • abasia
  • anaemia
  • anorexia
  • arthralgia
10-19:
  • agitation
  • hallucination
  • myoclonus
  • hyperthermia
  • intentional overdose
  • muscle rigidity
  • mydriasis
  • tremor
  • hypertension
  • rhabdomyolysis
20-29:
  • pain
  • pulmonary embolism
  • injury
  • cholelithiasis
  • anxiety
  • arthralgia
  • cholecystitis chronic
  • gallbladder disorder
  • oedema peripheral
  • abdominal pain upper
30-39:
  • diabetes mellitus
  • fatigue
  • pain in extremity
  • nausea
  • cholelithiasis
  • deep vein thrombosis
  • dyspnoea
  • pain
  • abdominal pain upper
  • arthralgia
40-49:
  • anxiety
  • pain
  • depression
  • diabetes mellitus
  • chest pain
  • dizziness
  • fatigue
  • back pain
  • completed suicide
  • insomnia
50-59:
  • nausea
  • back pain
  • osteoarthritis
  • paraesthesia
  • anxiety
  • dyspnoea
  • fatigue
  • headache
  • pain in extremity
  • pain
60+:
  • fall
  • pain
  • nausea
  • dizziness
  • drug ineffective
  • weight decreased
  • arthralgia
  • vomiting
  • anxiety
  • depression

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Wellbutrin (bupropion hydrochloride) is often used to treat depression. Aleve (naproxen sodium) is often used to treat arthritis. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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