Review: taking Wellbutrin and Vicodin together


Summary

Drug interactions are reported among people who take Wellbutrin and Vicodin together. This review analyzes the effectiveness and drug interactions between Wellbutrin and Vicodin. It is created by eHealthMe based on reports of 3,469 people who take the same drugs from FDA and social media, and is updated regularly.

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Wellbutrin

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from Wellbutrin 54,663 users)

Vicodin

Vicodin has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. (latest outcomes from Vicodin 34,634 users)

On Jul, 22, 2016

3,469 people who take Wellbutrin, Vicodin are studied.


Number of reports submitted per year:

Wellbutrin and Vicodin drug interactions.

Drug effectiveness over time:

Wellbutrin:
  • < 1 month: 10.0% - (4 of 37 people)
  • 1 - 6 months: 44.0% - (24 of 54 people)
  • 6 - 12 months: 31.0% - (12 of 38 people)
  • 1 - 2 years: 23.0% - (11 of 46 people)
  • 2 - 5 years: 58.0% - (83 of 143 people)
  • 5 - 10 years: 54.0% - (37 of 68 people)
  • 10+ years: 55.0% - (20 of 36 people)
  • not specified: 33.0% - (1 of 3 people)
Vicodin:
  • < 1 month: 44.0% - (25 of 56 people)
  • 1 - 6 months: 36.0% - (17 of 46 people)
  • 6 - 12 months: 28.0% - (6 of 21 people)
  • 1 - 2 years: 21.0% - (30 of 137 people)
  • 2 - 5 years: 43.0% - (37 of 85 people)
  • 5 - 10 years: 51.0% - (19 of 37 people)
  • 10+ years: 55.0% - (20 of 36 people)
  • not specified: 81.0% - (9 of 11 people)

Drug effectiveness by gender:

Wellbutrin:
  • female: 48.0% - (164 of 335 people)
  • male: 31.0% - (28 of 90 people)
Vicodin:
  • female: 35.0% - (121 of 342 people)
  • male: 48.0% - (42 of 87 people)

Drug effectiveness by age:

Wellbutrin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (4 of 4 people)
  • 20-29: 37.0% - (17 of 45 people)
  • 30-39: 67.0% - (91 of 134 people)
  • 40-49: 33.0% - (38 of 115 people)
  • 50-59: 33.0% - (33 of 98 people)
  • 60+: 31.0% - (9 of 29 people)
Vicodin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (4 of 4 people)
  • 20-29: 51.0% - (21 of 41 people)
  • 30-39: 19.0% - (26 of 134 people)
  • 40-49: 40.0% - (46 of 114 people)
  • 50-59: 50.0% - (53 of 104 people)
  • 60+: 40.0% - (13 of 32 people)

Most common drug interactions over time *:

< 1 month:
  • delirium
  • irritability
  • amnesia
  • anxiety
  • pain in extremity
  • respiratory failure
  • chest pain
  • drug ineffective
  • dyspnoea
  • impaired driving ability
1 - 6 months:
  • depression
  • oedema peripheral
  • drug ineffective
  • pain
  • headache
  • arthralgia
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • cataract
  • joint swelling
  • thyroid neoplasm
6 - 12 months:
  • anxiety
  • drug ineffective
  • fatigue
  • nausea
  • cerebrovascular accident
  • depression
  • haemorrhagic stroke
  • accident at work
  • adjustment disorder
  • autonomic dysreflexia
1 - 2 years:
  • nausea and vomiting
  • depression
  • anxiety
  • dizziness
  • injury
  • pain
  • anger
  • drug ineffective
  • emotional distress
  • general physical health deterioration
2 - 5 years:
  • nausea and vomiting
  • depression
  • anxiety
  • pain
  • suicidal ideation
  • suicide attempt
  • anger
  • headache
  • hypertension
  • constipation
5 - 10 years:
  • depression
  • anxiety
  • nausea
  • fatigue
  • sweating - excessive
  • vision blurred
  • hair loss
  • insomnia
  • pain
  • pain - joints
10+ years:
  • depression
  • failed back surgery syndrome
  • heart injury
  • herniated intervertebral disk
  • high blood cholesterol
  • seasonal allergy
  • pain
  • brain mass
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • fatigue
not specified:
  • pain
  • anxiety
  • depression
  • nausea
  • back pain
  • dyspnoea
  • fall
  • fatigue
  • insomnia
  • headache

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • depression
  • nausea
  • headache
  • fall
  • back pain
  • fatigue
  • dyspnoea
  • insomnia
male:
  • pain
  • anxiety
  • depression
  • dyspnoea
  • back pain
  • insomnia
  • constipation
  • pneumonia
  • nausea
  • weight decreased

Most common drug interactions by age *:

0-1:
  • suicide attempt
  • type 2 diabetes mellitus
  • deep vein thrombosis
  • drug exposure via breast milk
  • fall
  • haematochezia
  • hepatitis c
  • neuroleptic malignant syndrome
  • pulmonary embolism
  • systemic lupus erythematosus
2-9:
  • accidental exposure
  • blood pressure decreased
  • heart rate increased
  • rhinorrhoea
  • upper respiratory tract infection
  • white blood cell count decreased
10-19:
  • cholecystitis chronic
  • gallbladder disorder
  • pain
  • abdominal pain upper
  • cholecystitis
  • injury
  • cholelithiasis
  • deep vein thrombosis
  • anxiety
  • gallbladder cholesterolosis
20-29:
  • anxiety
  • chest pain
  • pain
  • deep vein thrombosis
  • depression
  • pulmonary embolism
  • abdominal pain upper
  • muscle spasms
  • cholecystitis chronic
  • nausea
30-39:
  • nausea and vomiting
  • depression
  • anxiety
  • nausea
  • pain
  • type 2 diabetes mellitus
  • weight increased
  • diabetes mellitus
  • insomnia
  • back pain
40-49:
  • depression
  • pain
  • anxiety
  • nausea
  • dyspnoea
  • back pain
  • chest pain
  • oedema peripheral
  • headache
  • fatigue
50-59:
  • pain
  • anxiety
  • nausea
  • depression
  • insomnia
  • fall
  • diarrhoea
  • headache
  • injury
  • osteoarthritis
60+:
  • anxiety
  • pneumonia
  • nausea
  • depression
  • arthralgia
  • pain
  • fatigue
  • dyspnoea
  • fall
  • vomiting

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Wellbutrin (bupropion hydrochloride) is often used to treat depression. Vicodin (acetaminophen; hydrocodone bitartrate) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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