Review: taking Wellbutrin and Zyrtec together


Summary

Drug interactions are reported among people who take Wellbutrin and Zyrtec together. This review analyzes the effectiveness and drug interactions between Wellbutrin and Zyrtec. It is created by eHealthMe based on reports of 1,993 people who take the same drugs from FDA and social media, and is updated regularly.

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Wellbutrin

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from Wellbutrin 69,043 users)

Zyrtec

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Zyrtec 46,713 users)

On Sep, 20, 2016

1,993 people who take Wellbutrin, Zyrtec are studied.


Number of reports submitted per year:

Wellbutrin and Zyrtec drug interactions.

Drug effectiveness over time:

Wellbutrin:
  • < 1 month: 42.0% - (3 of 7 people)
  • 1 - 6 months: 24.0% - (6 of 25 people)
  • 6 - 12 months: 58.0% - (7 of 12 people)
  • 1 - 2 years: 40.0% - (8 of 20 people)
  • 2 - 5 years: 59.0% - (16 of 27 people)
  • 5 - 10 years: 57.0% - (11 of 19 people)
  • 10+ years: 61.0% - (8 of 13 people)
  • not specified: 0.0% - (0 of 1 people)
Zyrtec:
  • < 1 month: 45.0% - (5 of 11 people)
  • 1 - 6 months: 10.0% - (1 of 10 people)
  • 6 - 12 months: 66.0% - (8 of 12 people)
  • 1 - 2 years: 35.0% - (6 of 17 people)
  • 2 - 5 years: 57.0% - (23 of 40 people)
  • 5 - 10 years: 68.0% - (13 of 19 people)
  • 10+ years: 69.0% - (9 of 13 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Wellbutrin:
  • female: 50.0% - (55 of 108 people)
  • male: 25.0% - (4 of 16 people)
Zyrtec:
  • female: 50.0% - (55 of 108 people)
  • male: 66.0% - (10 of 15 people)

Drug effectiveness by age:

Wellbutrin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 66.0% - (14 of 21 people)
  • 30-39: 28.0% - (9 of 32 people)
  • 40-49: 50.0% - (21 of 42 people)
  • 50-59: 47.0% - (9 of 19 people)
  • 60+: 55.0% - (5 of 9 people)
Zyrtec:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 57.0% - (12 of 21 people)
  • 30-39: 51.0% - (16 of 31 people)
  • 40-49: 45.0% - (19 of 42 people)
  • 50-59: 70.0% - (14 of 20 people)
  • 60+: 50.0% - (4 of 8 people)

Most common drug interactions over time *:

< 1 month:
  • depression
  • vertigo
  • drug ineffective
  • fatigue
  • headache
  • insomnia
  • rash
  • vertigo - positional
  • anxiety
  • congenital cystic kidney disease
1 - 6 months:
  • nausea
  • headache
  • dizziness
  • eyes - sensitive to light
  • headache - mixed tension migraine
  • lightheadedness - dizzy
  • muscle cramps aggravated
  • neuralgia
  • vomiting
  • congenital cystic kidney disease
6 - 12 months:
  • reflux gastritis
  • tinnitus
  • osteoarthritis
  • cervical root pain
  • convulsion
  • cor pulmonale chronic
  • cough
  • dry mouth
  • fatigue
  • gastrooesophageal reflux disease
1 - 2 years:
  • anxiety
  • tinnitus
  • difficulty in walking
  • hallucinations, mixed
  • muscle - jerky movements (uncontrolled)
  • paranoia
  • reflux gastritis
  • feeling cold
  • itching
  • lethargy
2 - 5 years:
  • vertigo
  • depression
  • eyes - sensitive to light
  • anxiety
  • headache - mixed tension migraine
  • lightheadedness - dizzy
  • muscle cramps aggravated
  • vertigo - positional
  • dyspepsia
  • insomnia
5 - 10 years:
  • difficulty in walking
  • depression
  • memory impairment
  • appetite increased
  • dizziness
  • drug ineffective
  • frequent headaches
  • insomnia
  • kidney small
  • libido decreased
10+ years:
  • headache
  • itching
  • feeling cold
  • lethargy
  • perianal fungal infection
  • ckd
  • high blood pressure
  • migraine
  • wheezing
  • abdominal pain
not specified:
  • pain
  • nausea
  • anxiety
  • depression
  • fatigue
  • fall
  • headache
  • dyspnoea
  • pain in extremity
  • back pain

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • nausea
  • headache
  • depression
  • fatigue
  • fall
  • dyspnoea
  • pain in extremity
  • arthralgia
male:
  • pain
  • nausea
  • depression
  • dyspnoea
  • anxiety
  • fatigue
  • headache
  • dizziness
  • pain in extremity
  • chest pain

Most common drug interactions by age *:

0-1:
  • abnormal behaviour
  • anxiety
  • balance disorder
  • bradycardia
  • cholecystitis chronic
  • convulsion
  • depression
  • diabetic complication
  • dyspnoea
  • hyponatraemia
2-9:
  • anhedonia
  • anxiety
  • arthritis
  • bronchitis
  • cholecystitis
  • deep vein thrombosis
  • difficulty in walking
  • dyskinesia
  • dystonia
  • emotional distress
10-19:
  • suicidal ideation
  • headache
  • anxiety
  • weight increased
  • nausea
  • obesity
  • feeling abnormal
  • diabetes mellitus
  • fatigue
  • agitation
20-29:
  • pain
  • injury
  • abdominal pain
  • anxiety
  • cholelithiasis
  • headache
  • nausea
  • cholecystitis chronic
  • cholecystitis acute
  • diabetes mellitus
30-39:
  • deep vein thrombosis
  • bronchitis
  • blood cholesterol increased
  • cholelithiasis
  • dizziness
  • depression
  • fatigue
  • blood alkaline phosphatase increased
  • abdominal pain
  • pain
40-49:
  • nausea
  • pain
  • anxiety
  • headache
  • back pain
  • drug ineffective
  • depression
  • diarrhoea
  • vomiting
  • fatigue
50-59:
  • pain
  • depression
  • headache
  • anxiety
  • nausea
  • fatigue
  • dizziness
  • arthralgia
  • fall
  • weight decreased
60+:
  • dyspnoea
  • fall
  • fatigue
  • pain
  • headache
  • nausea
  • drug ineffective
  • malaise
  • depression
  • cough

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Wellbutrin (bupropion hydrochloride) is often used to treat depression. Zyrtec (cetirizine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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