Review: taking Wellbutrin and Zyrtec together


Summary

Drug interactions are reported among people who take Wellbutrin and Zyrtec together. This review analyzes the effectiveness and drug interactions between Wellbutrin and Zyrtec. It is created by eHealthMe based on reports of 1,497 people who take the same drugs from FDA and social media, and is updated regularly.

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Wellbutrin

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from Wellbutrin 58,718 users)

Zyrtec

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Zyrtec 33,169 users)

On Aug, 18, 2016

1,497 people who take Wellbutrin, Zyrtec are studied.


Number of reports submitted per year:

Wellbutrin and Zyrtec drug interactions.

Drug effectiveness over time:

Wellbutrin:
  • < 1 month: 42.0% - (3 of 7 people)
  • 1 - 6 months: 24.0% - (6 of 25 people)
  • 6 - 12 months: 58.0% - (7 of 12 people)
  • 1 - 2 years: 40.0% - (8 of 20 people)
  • 2 - 5 years: 59.0% - (16 of 27 people)
  • 5 - 10 years: 57.0% - (11 of 19 people)
  • 10+ years: 61.0% - (8 of 13 people)
  • not specified: 0.0% - (0 of 1 people)
Zyrtec:
  • < 1 month: 45.0% - (5 of 11 people)
  • 1 - 6 months: 10.0% - (1 of 10 people)
  • 6 - 12 months: 66.0% - (8 of 12 people)
  • 1 - 2 years: 35.0% - (6 of 17 people)
  • 2 - 5 years: 57.0% - (23 of 40 people)
  • 5 - 10 years: 68.0% - (13 of 19 people)
  • 10+ years: 69.0% - (9 of 13 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Wellbutrin:
  • female: 50.0% - (55 of 108 people)
  • male: 25.0% - (4 of 16 people)
Zyrtec:
  • female: 50.0% - (55 of 108 people)
  • male: 66.0% - (10 of 15 people)

Drug effectiveness by age:

Wellbutrin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 66.0% - (14 of 21 people)
  • 30-39: 28.0% - (9 of 32 people)
  • 40-49: 50.0% - (21 of 42 people)
  • 50-59: 47.0% - (9 of 19 people)
  • 60+: 55.0% - (5 of 9 people)
Zyrtec:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 57.0% - (12 of 21 people)
  • 30-39: 51.0% - (16 of 31 people)
  • 40-49: 45.0% - (19 of 42 people)
  • 50-59: 70.0% - (14 of 20 people)
  • 60+: 50.0% - (4 of 8 people)

Most common drug interactions over time *:

< 1 month:
  • depression
  • vertigo
  • drug ineffective
  • fatigue
  • insomnia
  • vertigo - positional
  • congenital cystic kidney disease
  • dizziness
  • rash
  • suicidal ideation
1 - 6 months:
  • nausea
  • headache
  • dizziness
  • eyes - sensitive to light
  • headache - mixed tension migraine
  • lightheadedness - dizzy
  • muscle cramps aggravated
  • vomiting
  • congenital cystic kidney disease
  • depression
6 - 12 months:
  • reflux gastritis
  • tinnitus
  • cervical root pain
  • convulsion
  • cor pulmonale chronic
  • cough
  • dry mouth
  • fatigue
  • gastrooesophageal reflux disease
  • hallucination, olfactory
1 - 2 years:
  • anxiety
  • tinnitus
  • difficulty in walking
  • hallucinations, mixed
  • muscle - jerky movements (uncontrolled)
  • paranoia
  • reflux gastritis
  • feeling cold
  • itching
  • lethargy
2 - 5 years:
  • vertigo
  • depression
  • eyes - sensitive to light
  • headache - mixed tension migraine
  • lightheadedness - dizzy
  • muscle cramps aggravated
  • vertigo - positional
  • anxiety
  • dyspepsia
  • insomnia
5 - 10 years:
  • difficulty in walking
  • depression
  • memory impairment
  • appetite increased
  • dizziness
  • drug ineffective
  • frequent headaches
  • insomnia
  • kidney small
  • libido decreased
10+ years:
  • headache
  • itching
  • feeling cold
  • lethargy
  • perianal fungal infection
  • ckd
  • high blood pressure
  • wheezing
  • arthralgia
  • chills
not specified:
  • pain
  • anxiety
  • nausea
  • depression
  • fatigue
  • fall
  • dyspnoea
  • pain in extremity
  • back pain
  • headache

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • depression
  • fatigue
  • nausea
  • headache
  • fall
  • arthralgia
  • pain in extremity
  • dyspnoea
male:
  • pain
  • dyspnoea
  • anxiety
  • depression
  • nausea
  • dizziness
  • drug ineffective
  • pain in extremity
  • abdominal pain
  • chest pain

Most common drug interactions by age *:

0-1:
  • balance disorder
  • bradycardia
  • cholecystitis chronic
  • convulsion
  • diabetic complication
  • dyspnoea
  • hyponatraemia
  • hypotension
  • nervous system disorder
  • orthopnoea
2-9:
  • difficulty in walking
  • dyskinesia
  • dystonia
  • eye movement disorder
  • muscle spasms
10-19:
  • suicidal ideation
  • anxiety
  • feeling abnormal
  • weight increased
  • diabetes mellitus
  • obesity
  • convulsion
  • drug ineffective
  • dysgeusia
  • headache
20-29:
  • pain
  • injury
  • anxiety
  • cholelithiasis
  • abdominal pain
  • cholecystitis chronic
  • cholecystitis acute
  • diabetes mellitus
  • diabetic ketoacidosis
  • nausea
30-39:
  • bronchitis
  • blood cholesterol increased
  • cholelithiasis
  • deep vein thrombosis
  • depression
  • dizziness
  • abdominal pain
  • blood alkaline phosphatase increased
  • fatigue
  • insomnia
40-49:
  • pain
  • nausea
  • anxiety
  • back pain
  • headache
  • anaemia
  • drug ineffective
  • osteonecrosis of jaw
  • vomiting
  • oedema peripheral
50-59:
  • pain
  • depression
  • headache
  • anxiety
  • dizziness
  • arthralgia
  • nausea
  • fatigue
  • weight decreased
  • dyspnoea
60+:
  • fall
  • fatigue
  • drug ineffective
  • pain
  • dyspnoea
  • depression
  • anxiety
  • nausea
  • chest discomfort
  • malaise

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Wellbutrin (bupropion hydrochloride) is often used to treat depression. Zyrtec (cetirizine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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