Review: taking Xanax and Flexeril together


Summary

Drug interactions are reported among people who take Xanax and Flexeril together. This review analyzes the effectiveness and drug interactions between Xanax and Flexeril. It is created by eHealthMe based on reports of 5,041 people who take the same drugs from FDA and social media, and is updated regularly.

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Xanax

Xanax has active ingredients of alprazolam. It is often used in stress and anxiety. (latest outcomes from Xanax 82,506 users)

Flexeril

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. (latest outcomes from Flexeril 24,055 users)

On Sep, 17, 2016

5,041 people who take Xanax, Flexeril are studied.


Number of reports submitted per year:

Xanax and Flexeril drug interactions.

Drug effectiveness over time:

Xanax:
  • < 1 month: 33.0% - (3 of 9 people)
  • 1 - 6 months: 27.0% - (6 of 22 people)
  • 6 - 12 months: 55.0% - (5 of 9 people)
  • 1 - 2 years: 50.0% - (13 of 26 people)
  • 2 - 5 years: 58.0% - (20 of 34 people)
  • 5 - 10 years: 47.0% - (11 of 23 people)
  • 10+ years: 83.0% - (10 of 12 people)
  • not specified: 0.0% - (0 of 1 people)
Flexeril:
  • < 1 month: 22.0% - (6 of 27 people)
  • 1 - 6 months: 14.0% - (4 of 27 people)
  • 6 - 12 months: 18.0% - (2 of 11 people)
  • 1 - 2 years: 26.0% - (5 of 19 people)
  • 2 - 5 years: 30.0% - (6 of 20 people)
  • 5 - 10 years: 35.0% - (5 of 14 people)
  • 10+ years: 28.0% - (2 of 7 people)
  • not specified: 0.0% - (0 of 2 people)

Drug effectiveness by gender:

Xanax:
  • female: 52.0% - (57 of 108 people)
  • male: 39.0% - (11 of 28 people)
Flexeril:
  • female: 23.0% - (23 of 100 people)
  • male: 25.0% - (7 of 27 people)

Drug effectiveness by age:

Xanax:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 50.0% - (6 of 12 people)
  • 30-39: 53.0% - (23 of 43 people)
  • 40-49: 46.0% - (18 of 39 people)
  • 50-59: 54.0% - (18 of 33 people)
  • 60+: 37.0% - (3 of 8 people)
Flexeril:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 18.0% - (2 of 11 people)
  • 30-39: 17.0% - (7 of 39 people)
  • 40-49: 35.0% - (13 of 37 people)
  • 50-59: 16.0% - (5 of 31 people)
  • 60+: 37.0% - (3 of 8 people)

Most common drug interactions over time *:

< 1 month:
  • memory impairment
  • depression
  • dyspnoea
  • pain
  • vomiting
  • suicide attempt
  • drug toxicity
  • somnolence
  • intentional overdose
  • injury
1 - 6 months:
  • pain
  • pulmonary embolism
  • deep vein thrombosis
  • drug ineffective
  • completed suicide
  • death
  • detoxification
  • dizziness
  • syncope
  • vomiting
6 - 12 months:
  • nausea
  • blood pressure increased
  • vomiting
  • hormone level abnormal
  • anxiety
  • chest pain
  • confusional state
  • depression
  • headache
  • hyperhidrosis
1 - 2 years:
  • nausea
  • syncope
  • chest pain
  • pain
  • anxiety
  • asthenia
  • dizziness
  • drug ineffective
  • dyspnoea
  • injury
2 - 5 years:
  • depression
  • pain
  • anxiety
  • degenerative joint disease
  • nausea
  • suicide attempt
  • back injury
  • anxiety disorder due to a general medical condition
  • intentional overdose
  • lumbar spinal stenosis
5 - 10 years:
  • anxiety
  • pain
  • anxiety disorder due to a general medical condition
  • back injury
  • degenerative joint disease
  • lumbar spinal stenosis
  • major depressive disorder
  • emotional distress
  • cyanosis
  • drug hypersensitivity
10+ years:
  • arthropathy
  • type 2 diabetes mellitus
  • confusional state
  • depression
  • joint pain
  • joint swelling
  • migraine
  • pain in fingers
  • periarthritis
  • seizure
not specified:
  • pain
  • anxiety
  • nausea
  • depression
  • fatigue
  • back pain
  • dyspnoea
  • fall
  • headache
  • diarrhoea

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • nausea
  • depression
  • fatigue
  • back pain
  • fall
  • headache
  • dyspnoea
  • diarrhoea
male:
  • pain
  • depression
  • anxiety
  • insomnia
  • nausea
  • dyspnoea
  • pain in extremity
  • fatigue
  • vomiting
  • back pain

Most common drug interactions by age *:

0-1:
  • diabetes mellitus
  • herpes zoster
2-9:
  • scar
  • dyspnoea
  • vomiting
  • emotional distress
  • myalgia
  • emotional disorder
  • headache
  • pyrexia
  • tardive dyskinesia
  • acute sinusitis
10-19:
  • cardiac arrest
  • respiratory arrest
  • completed suicide
  • drug abuse
  • cardio-respiratory arrest
  • pain
  • cholecystitis chronic
  • gallbladder disorder
  • pancreatitis
  • sphincter of oddi dysfunction
20-29:
  • pain
  • anxiety
  • injury
  • nausea
  • vomiting
  • completed suicide
  • pulmonary embolism
  • insomnia
  • oedema peripheral
  • pain in extremity
30-39:
  • nausea
  • anxiety
  • depression
  • pain
  • dyspnoea
  • drug abuse
  • deep vein thrombosis
  • arthralgia
  • asthenia
  • headache
40-49:
  • pain
  • nausea
  • depression
  • anxiety
  • headache
  • chest pain
  • back pain
  • dyspnoea
  • fatigue
  • drug ineffective
50-59:
  • pain
  • anxiety
  • nausea
  • fatigue
  • depression
  • back pain
  • headache
  • arthralgia
  • weight decreased
  • fall
60+:
  • pain
  • anxiety
  • fall
  • dyspnoea
  • hypertension
  • back pain
  • diarrhoea
  • osteoarthritis
  • fatigue
  • anhedonia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Xanax and Flexeril?

Can you answer these questions?

More questions for: Xanax, Flexeril

You may be interested in these reviews

More reviews for: Xanax, Flexeril

On eHealthMe, Xanax (alprazolam) is often used to treat stress and anxiety. Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.