Review: taking Xanax and Synthroid together


Summary

Drug interactions are reported among people who take Xanax and Synthroid together. This review analyzes the effectiveness and drug interactions between Xanax and Synthroid. It is created by eHealthMe based on reports of 10,665 people who take the same drugs from FDA and social media, and is updated regularly.

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Xanax

Xanax has active ingredients of alprazolam. It is often used in stress and anxiety. (latest outcomes from Xanax 67,594 users)

Synthroid

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. (latest outcomes from Synthroid 107,543 users)

On Aug, 27, 2016

10,665 people who take Xanax, Synthroid are studied.


Number of reports submitted per year:

Xanax and Synthroid drug interactions.

Drug effectiveness over time:

Xanax:
  • < 1 month: 37.0% - (9 of 24 people)
  • 1 - 6 months: 58.0% - (25 of 43 people)
  • 6 - 12 months: 55.0% - (25 of 45 people)
  • 1 - 2 years: 52.0% - (36 of 69 people)
  • 2 - 5 years: 56.0% - (42 of 75 people)
  • 5 - 10 years: 67.0% - (48 of 71 people)
  • 10+ years: 67.0% - (45 of 67 people)
  • not specified: 100.0% - (2 of 2 people)
Synthroid:
  • < 1 month: 20.0% - (2 of 10 people)
  • 1 - 6 months: 32.0% - (9 of 28 people)
  • 6 - 12 months: 50.0% - (12 of 24 people)
  • 1 - 2 years: 40.0% - (14 of 35 people)
  • 2 - 5 years: 49.0% - (33 of 67 people)
  • 5 - 10 years: 57.0% - (56 of 98 people)
  • 10+ years: 71.0% - (90 of 126 people)
  • not specified: 100.0% - (2 of 2 people)

Drug effectiveness by gender:

Xanax:
  • female: 60.0% - (208 of 346 people)
  • male: 48.0% - (24 of 50 people)
Synthroid:
  • female: 54.0% - (185 of 341 people)
  • male: 67.0% - (33 of 49 people)

Drug effectiveness by age:

Xanax:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 62.0% - (10 of 16 people)
  • 30-39: 60.0% - (46 of 76 people)
  • 40-49: 58.0% - (55 of 94 people)
  • 50-59: 65.0% - (69 of 106 people)
  • 60+: 50.0% - (52 of 103 people)
Synthroid:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 68.0% - (11 of 16 people)
  • 30-39: 54.0% - (40 of 73 people)
  • 40-49: 55.0% - (50 of 90 people)
  • 50-59: 53.0% - (59 of 110 people)
  • 60+: 58.0% - (58 of 100 people)

Most common drug interactions over time *:

< 1 month:
  • diarrhoea
  • anxiety
  • nausea
  • abdominal pain
  • weight decreased
  • intentional overdose
  • suicide attempt
  • panic attack
  • fatigue
  • dizziness
1 - 6 months:
  • nausea
  • dizziness
  • chest pain
  • depression
  • fatigue
  • anxiety
  • alanine aminotransferase increased
  • deep vein thrombosis
  • abdominal pain
  • asthenia
6 - 12 months:
  • nausea
  • dizziness
  • insomnia
  • involuntary body movements
  • mouth dry aggravated
  • stuttering
  • tremor - drug-induced
  • joint pain
  • shortness of breath
  • constipation
1 - 2 years:
  • palpitations
  • dizziness
  • anxiety
  • nausea
  • asthenia
  • depression
  • confusion
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • hypothyroidism
  • muscle twitching
2 - 5 years:
  • depression
  • anxiety
  • insomnia
  • anger
  • pain
  • suicidal ideation
  • headache
  • road traffic accident
  • constipation
  • hallucination
5 - 10 years:
  • depression
  • anxiety
  • dizziness
  • fatigue - chronic
  • fatigue
  • loss of sensation, numbness and tingling, paresthesias, sensory loss, tingling and numbness
  • muscle pain
  • tremor
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • hypothyroidism
10+ years:
  • anxiety
  • deep vein thrombosis
  • pulmonary embolism
  • pain
  • mobility decreased
  • swelling
  • impaired driving ability
  • post thrombotic syndrome
  • agitation
  • fear
not specified:
  • nausea
  • pain
  • fatigue
  • anxiety
  • dyspnoea
  • depression
  • headache
  • drug ineffective
  • asthenia
  • fall

Most common drug interactions by gender *:

female:
  • nausea
  • pain
  • fatigue
  • anxiety
  • dyspnoea
  • depression
  • headache
  • fall
  • drug ineffective
  • dizziness
male:
  • fatigue
  • dyspnoea
  • depression
  • anxiety
  • dizziness
  • nausea
  • asthenia
  • chest pain
  • drug ineffective
  • pain

Most common drug interactions by age *:

0-1:
  • thyroid disorder
  • accident
  • arthritis
  • coma
  • foetal exposure during pregnancy
  • hepatic steatosis
  • homicidal ideation
  • hypertension
  • impaired gastric emptying
  • impaired work ability
2-9:
  • abdominal pain upper
  • acute stress disorder
  • adverse drug reaction
  • ankle fracture
  • anxiety
  • arthropathy
  • asthenia
  • benign intracranial hypertension
  • bipolar disorder
  • bipolar i disorder
10-19:
  • drug ineffective
  • anxiety
  • pain
  • depression
  • palpitations
  • drug administration error
  • weight increased
  • back pain
  • cholecystitis chronic
  • gastrooesophageal reflux disease
20-29:
  • pain
  • anxiety
  • cholecystitis chronic
  • cholelithiasis
  • nausea
  • injury
  • fatigue
  • headache
  • deep vein thrombosis
  • depression
30-39:
  • anxiety
  • fatigue
  • depression
  • pain
  • dyspnoea
  • insomnia
  • headache
  • nausea
  • asthenia
  • constipation
40-49:
  • nausea
  • anxiety
  • pain
  • depression
  • fatigue
  • headache
  • vomiting
  • chest pain
  • weight increased
  • arthralgia
50-59:
  • nausea
  • anxiety
  • pain
  • depression
  • fatigue
  • headache
  • dyspnoea
  • oedema peripheral
  • dizziness
  • pneumonia
60+:
  • fatigue
  • nausea
  • dyspnoea
  • asthenia
  • dizziness
  • pain
  • fall
  • drug ineffective
  • anxiety
  • headache

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Xanax (alprazolam) is often used to treat stress and anxiety. Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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