Review: taking Xanax and Synthroid together


Summary

Drug interactions are reported among people who take Xanax and Synthroid together. This review analyzes the effectiveness and drug interactions between Xanax and Synthroid. It is created by eHealthMe based on reports of 13,619 people who take the same drugs from FDA and social media, and is updated regularly.

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Xanax

Xanax has active ingredients of alprazolam. It is often used in stress and anxiety. (latest outcomes from Xanax 82,506 users)

Synthroid

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. (latest outcomes from Synthroid 133,829 users)

On Sep, 18, 2016

13,619 people who take Xanax, Synthroid are studied.


Number of reports submitted per year:

Xanax and Synthroid drug interactions.

Drug effectiveness over time:

Xanax:
  • < 1 month: 37.0% - (9 of 24 people)
  • 1 - 6 months: 58.0% - (25 of 43 people)
  • 6 - 12 months: 55.0% - (25 of 45 people)
  • 1 - 2 years: 52.0% - (36 of 69 people)
  • 2 - 5 years: 56.0% - (42 of 75 people)
  • 5 - 10 years: 67.0% - (48 of 71 people)
  • 10+ years: 67.0% - (45 of 67 people)
  • not specified: 100.0% - (2 of 2 people)
Synthroid:
  • < 1 month: 20.0% - (2 of 10 people)
  • 1 - 6 months: 32.0% - (9 of 28 people)
  • 6 - 12 months: 50.0% - (12 of 24 people)
  • 1 - 2 years: 40.0% - (14 of 35 people)
  • 2 - 5 years: 49.0% - (33 of 67 people)
  • 5 - 10 years: 57.0% - (56 of 98 people)
  • 10+ years: 71.0% - (90 of 126 people)
  • not specified: 100.0% - (2 of 2 people)

Drug effectiveness by gender:

Xanax:
  • female: 60.0% - (208 of 346 people)
  • male: 48.0% - (24 of 50 people)
Synthroid:
  • female: 54.0% - (185 of 341 people)
  • male: 67.0% - (33 of 49 people)

Drug effectiveness by age:

Xanax:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 62.0% - (10 of 16 people)
  • 30-39: 60.0% - (46 of 76 people)
  • 40-49: 58.0% - (55 of 94 people)
  • 50-59: 65.0% - (69 of 106 people)
  • 60+: 50.0% - (52 of 103 people)
Synthroid:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 68.0% - (11 of 16 people)
  • 30-39: 54.0% - (40 of 73 people)
  • 40-49: 55.0% - (50 of 90 people)
  • 50-59: 53.0% - (59 of 110 people)
  • 60+: 58.0% - (58 of 100 people)

Most common drug interactions over time *:

< 1 month:
  • diarrhoea
  • anxiety
  • nausea
  • abdominal pain
  • intentional overdose
  • weight decreased
  • fatigue
  • panic attack
  • suicide attempt
  • headache
1 - 6 months:
  • fatigue
  • nausea
  • dizziness
  • anxiety
  • chest pain
  • depression
  • muscle spasms
  • deep vein thrombosis
  • hypertension
  • insomnia
6 - 12 months:
  • nausea
  • dizziness
  • insomnia
  • involuntary body movements
  • mouth dry aggravated
  • stuttering
  • tremor - drug-induced
  • fatigue
  • joint pain
  • shortness of breath
1 - 2 years:
  • palpitations
  • dizziness
  • anxiety
  • asthenia
  • nausea
  • depression
  • pain
  • confusion
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • fatigue
2 - 5 years:
  • depression
  • anxiety
  • pain
  • insomnia
  • anger
  • headache
  • suicidal ideation
  • amnesia
  • constipation
  • hallucination
5 - 10 years:
  • depression
  • anxiety
  • dizziness
  • fatigue - chronic
  • fatigue
  • hypothyroidism
  • loss of sensation, numbness and tingling, paresthesias, sensory loss, tingling and numbness
  • muscle pain
  • tremor
  • exhaustion, fatigue, lethargy, tiredness, weariness
10+ years:
  • anxiety
  • pulmonary embolism
  • deep vein thrombosis
  • pain
  • mobility decreased
  • swelling
  • fatigue
  • impaired driving ability
  • post thrombotic syndrome
  • agitation
not specified:
  • nausea
  • fatigue
  • pain
  • dyspnoea
  • anxiety
  • drug ineffective
  • headache
  • depression
  • fall
  • dizziness

Most common drug interactions by gender *:

female:
  • nausea
  • fatigue
  • pain
  • anxiety
  • dyspnoea
  • headache
  • drug ineffective
  • depression
  • fall
  • dizziness
male:
  • fatigue
  • dyspnoea
  • dizziness
  • drug ineffective
  • anxiety
  • depression
  • nausea
  • asthenia
  • chest pain
  • pain

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • thyroid disorder
  • accident
  • apnoea
  • arthritis
  • asthenia
  • attention deficit/hyperactivity disorder
  • bronchitis
  • cardiac arrest
  • cardiac murmur
2-9:
  • anaemia
  • blindness transient
  • drug hypersensitivity
  • dyspepsia
  • gastrooesophageal reflux disease
  • haematocrit decreased
  • haemoglobin decreased
  • rash
  • vision blurred
  • abdominal pain upper
10-19:
  • pain
  • anxiety
  • drug ineffective
  • arthralgia
  • fatigue
  • insomnia
  • pneumonia
  • alopecia
  • chest pain
  • gastrooesophageal reflux disease
20-29:
  • pain
  • anxiety
  • injury
  • nausea
  • cholecystitis chronic
  • fatigue
  • cholelithiasis
  • headache
  • drug ineffective
  • abdominal pain
30-39:
  • anxiety
  • fatigue
  • pain
  • depression
  • dyspnoea
  • insomnia
  • fall
  • headache
  • nausea
  • pulmonary embolism
40-49:
  • nausea
  • anxiety
  • pain
  • fatigue
  • headache
  • depression
  • vomiting
  • weight increased
  • chest pain
  • drug ineffective
50-59:
  • nausea
  • pain
  • anxiety
  • fatigue
  • depression
  • headache
  • dyspnoea
  • fall
  • dizziness
  • pneumonia
60+:
  • fatigue
  • dyspnoea
  • nausea
  • asthenia
  • pain
  • dizziness
  • drug ineffective
  • fall
  • diarrhoea
  • anxiety

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Xanax (alprazolam) is often used to treat stress and anxiety. Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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