Review: taking Xanax and Synthroid together


Summary

Drug interactions are reported among people who take Xanax and Synthroid together. This review analyzes the effectiveness and drug interactions between Xanax and Synthroid. It is created by eHealthMe based on reports of 8,955 people who take the same drugs from FDA and social media, and is updated regularly.

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Xanax

Xanax has active ingredients of alprazolam. It is often used in stress and anxiety. (latest outcomes from Xanax 58,024 users)

Synthroid

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. (latest outcomes from Synthroid 92,449 users)

On Jul, 21, 2016

8,955 people who take Xanax, Synthroid are studied.


Number of reports submitted per year:

Xanax and Synthroid drug interactions.

Drug effectiveness over time:

Xanax:
  • < 1 month: 54.0% - (19 of 35 people)
  • 1 - 6 months: 65.0% - (39 of 60 people)
  • 6 - 12 months: 63.0% - (37 of 58 people)
  • 1 - 2 years: 53.0% - (44 of 83 people)
  • 2 - 5 years: 59.0% - (58 of 98 people)
  • 5 - 10 years: 70.0% - (70 of 100 people)
  • 10+ years: 70.0% - (65 of 92 people)
  • not specified: 100.0% - (2 of 2 people)
Synthroid:
  • < 1 month: 12.0% - (2 of 16 people)
  • 1 - 6 months: 40.0% - (19 of 47 people)
  • 6 - 12 months: 44.0% - (13 of 29 people)
  • 1 - 2 years: 37.0% - (14 of 37 people)
  • 2 - 5 years: 47.0% - (43 of 90 people)
  • 5 - 10 years: 58.0% - (71 of 121 people)
  • 10+ years: 69.0% - (121 of 174 people)
  • not specified: 100.0% - (2 of 2 people)

Drug effectiveness by gender:

Xanax:
  • female: 65.0% - (299 of 460 people)
  • male: 51.0% - (35 of 68 people)
Synthroid:
  • female: 53.0% - (240 of 450 people)
  • male: 68.0% - (45 of 66 people)

Drug effectiveness by age:

Xanax:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 2 people)
  • 20-29: 75.0% - (18 of 24 people)
  • 30-39: 61.0% - (52 of 84 people)
  • 40-49: 63.0% - (78 of 122 people)
  • 50-59: 73.0% - (112 of 152 people)
  • 60+: 51.0% - (74 of 144 people)
Synthroid:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 2 people)
  • 20-29: 54.0% - (13 of 24 people)
  • 30-39: 53.0% - (42 of 79 people)
  • 40-49: 57.0% - (67 of 117 people)
  • 50-59: 54.0% - (86 of 157 people)
  • 60+: 56.0% - (77 of 137 people)

Most common drug interactions over time *:

< 1 month:
  • diarrhoea
  • anxiety
  • nausea
  • intentional overdose
  • suicide attempt
  • weight decreased
  • abdominal pain
  • panic attack
  • fatigue
  • dizziness
1 - 6 months:
  • nausea
  • chest pain
  • dizziness
  • fatigue
  • depression
  • anxiety
  • abdominal pain
  • fatigue aggravated
  • headache - mixed tension migraine
  • alanine aminotransferase increased
6 - 12 months:
  • nausea
  • dizziness
  • involuntary body movements
  • mouth dry aggravated
  • stuttering
  • tremor - drug-induced
  • insomnia
  • joint pain
  • shortness of breath
  • constipation
1 - 2 years:
  • palpitations
  • dizziness
  • anxiety
  • nausea
  • asthenia
  • depression
  • confusion
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • hypothyroidism
  • muscle twitching
2 - 5 years:
  • depression
  • anxiety
  • insomnia
  • anger
  • pain
  • suicidal ideation
  • headache
  • road traffic accident
  • constipation
  • hallucination
5 - 10 years:
  • depression
  • anxiety
  • dizziness
  • fatigue - chronic
  • fatigue
  • loss of sensation, numbness and tingling, paresthesias, sensory loss, tingling and numbness
  • tremor
  • hypothyroidism
  • muscle pain
  • muscle twitching
10+ years:
  • anxiety
  • deep vein thrombosis
  • pulmonary embolism
  • pain
  • mobility decreased
  • swelling
  • impaired driving ability
  • post thrombotic syndrome
  • agitation
  • fatigue
not specified:
  • nausea
  • fatigue
  • pain
  • anxiety
  • dyspnoea
  • depression
  • asthenia
  • headache
  • dizziness
  • fall

Most common drug interactions by gender *:

female:
  • nausea
  • pain
  • anxiety
  • fatigue
  • dyspnoea
  • depression
  • headache
  • dizziness
  • asthenia
  • fall
male:
  • dizziness
  • depression
  • fatigue
  • anxiety
  • dyspnoea
  • asthenia
  • chest pain
  • nausea
  • drug ineffective
  • diarrhoea

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • thyroid disorder
2-9:
  • benign intracranial hypertension
  • convulsion
  • headache
  • hyponatraemia
10-19:
  • drug ineffective
  • anxiety
  • alopecia
  • blood thyroid stimulating hormone increased
  • disturbance in attention
  • drug administration error
  • hypoaesthesia
  • memory impairment
  • mood swings
  • palpitations
20-29:
  • pain
  • cholecystitis chronic
  • anxiety
  • cholelithiasis
  • nausea
  • fatigue
  • deep vein thrombosis
  • headache
  • constipation
  • weight increased
30-39:
  • anxiety
  • depression
  • fatigue
  • pain
  • dyspnoea
  • insomnia
  • headache
  • asthenia
  • constipation
  • weight increased
40-49:
  • nausea
  • anxiety
  • depression
  • pain
  • fatigue
  • headache
  • vomiting
  • chest pain
  • weight increased
  • arthralgia
50-59:
  • nausea
  • anxiety
  • pain
  • depression
  • fatigue
  • headache
  • oedema peripheral
  • dyspnoea
  • pneumonia
  • chest pain
60+:
  • fatigue
  • nausea
  • asthenia
  • dyspnoea
  • dizziness
  • pain
  • fall
  • anxiety
  • drug ineffective
  • headache

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Xanax (alprazolam) is often used to treat stress and anxiety. Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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