Review: taking Xarelto and Aspirin together


Summary

Drug interactions are reported among people who take Xarelto and Aspirin together. This review analyzes the effectiveness and drug interactions between Xarelto and Aspirin. It is created by eHealthMe based on reports of 624 people who take the same drugs from FDA and social media, and is updated regularly.

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Xarelto

Xarelto has active ingredients of rivaroxaban. It is often used in atrial fibrillation/flutter. (latest outcomes from Xarelto 4,204 users)

Aspirin

Aspirin has active ingredients of aspirin. It is often used in preventive health care. (latest outcomes from Aspirin 157,331 users)

On Jul, 28, 2016

624 people who take Xarelto, Aspirin are studied.


Number of reports submitted per year:

Xarelto and Aspirin drug interactions.

Drug effectiveness over time:

Xarelto:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 25.0% - (1 of 4 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 25.0% - (1 of 4 people)
  • 2 - 5 years: 100.0% - (2 of 2 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Aspirin:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 11.0% - (1 of 9 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 100.0% - (7 of 7 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Xarelto:
  • female: 14.0% - (1 of 7 people)
  • male: 66.0% - (4 of 6 people)
Aspirin:
  • female: 11.0% - (1 of 9 people)
  • male: 70.0% - (7 of 10 people)

Drug effectiveness by age:

Xarelto:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 3 people)
  • 60+: 50.0% - (5 of 10 people)
Aspirin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 3 people)
  • 60+: 50.0% - (8 of 16 people)

Most common drug interactions over time *:

< 1 month:
  • gastrointestinal haemorrhage
  • haemoglobin decreased
  • hypotension
  • deep vein thrombosis
  • pulmonary embolism
  • oesophagitis haemorrhagic
  • dyspnoea
  • blood creatinine increased
  • cerebrovascular accident
  • melaena
1 - 6 months:
  • fall
  • iron deficiency anaemia
  • anaemia
  • gastrointestinal haemorrhage
  • decreased appetite
  • nausea
  • pulmonary embolism
  • haematuria
  • melaena
  • coagulopathy
6 - 12 months:
  • peritoneal haemorrhage
  • groin infection
  • hematuria
  • hemiparesis
  • hepatic failure
  • maternal exposure during pregnancy
  • microcytic anaemia
  • angioplasty
  • colon cancer
  • dysphonia
1 - 2 years:
  • diarrhoea
  • liver injury
  • vomiting
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • blood alkaline phosphatase increased
  • gamma-glutamyltransferase increased
  • hyperbilirubinaemia
  • jaundice
  • haemorrhage intracranial
2 - 5 years:
  • blood pressure fluctuation
  • blurred vision
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • foot pain
  • frequent headaches
  • gout
  • hair loss
  • hoarseness
  • swelling of the ankles - feet - legs
  • tinnitus
5 - 10 years:
  • haemoglobin decreased
  • haemorrhage
  • melaena
  • upper gastrointestinal haemorrhage
  • fainting
  • nocturia
  • short-term memory loss
10+ years:
  • anaemia
  • coagulopathy
  • hypokalaemia
  • interstitial lung disease
  • respiratory failure
  • breathlessness
  • sickness
  • atrial fibrillation
  • blood glucose increased
  • disease progression
not specified:
  • gastrointestinal haemorrhage
  • haemoglobin decreased
  • epistaxis
  • pulmonary embolism
  • haemorrhage
  • hypotension
  • dyspnoea
  • nausea
  • anaemia
  • haematuria

Most common drug interactions by gender *:

female:
  • gastrointestinal haemorrhage
  • hypotension
  • pulmonary embolism
  • haemoglobin decreased
  • deep vein thrombosis
  • oesophagitis haemorrhagic
  • nausea
  • abdominal pain
  • epistaxis
  • melaena
male:
  • gastrointestinal haemorrhage
  • haemoglobin decreased
  • pulmonary embolism
  • anaemia
  • epistaxis
  • dyspnoea
  • blood creatinine increased
  • haematuria
  • upper gastrointestinal haemorrhage
  • haemorrhage

Most common drug interactions by age *:

30-39:
  • circulatory collapse
  • dizziness
  • nausea
  • gastrointestinal haemorrhage
40-49:
  • in-stent coronary artery restenosis
  • pancreatitis acute
  • upper gastrointestinal haemorrhage
  • neutropenic infection
  • haemorrhagic transformation stroke
  • intracardiac thrombus
50-59:
  • gastrointestinal haemorrhage
  • gastritis erosive
  • hepatic enzyme increased
  • jaundice cholestatic
  • haemorrhagic stroke
  • sudden death
  • peritoneal haemorrhage
  • angina unstable
  • haemoptysis
  • thrombocytopenia
60+:
  • gastrointestinal haemorrhage
  • haemoglobin decreased
  • hypotension
  • pulmonary embolism
  • epistaxis
  • anaemia
  • deep vein thrombosis
  • dyspnoea
  • blood creatinine increased
  • melaena

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Xarelto (rivaroxaban) is often used to treat atrial fibrillation/flutter. Aspirin (aspirin) is often used to treat preventive health care. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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