Review: taking Zanaflex and Ms contin together


Summary

Drug interactions are reported among people who take Zanaflex and Ms contin together. This review analyzes the effectiveness and drug interactions between Zanaflex and Ms contin. It is created by eHealthMe based on reports of 916 people who take the same drugs from FDA and social media, and is updated regularly.

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Zanaflex

Zanaflex has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. (latest outcomes from Zanaflex 8,329 users)

Ms Contin

Ms contin has active ingredients of morphine sulfate. It is often used in pain. (latest outcomes from Ms contin 8,876 users)

On Aug, 25, 2016

916 people who take Zanaflex, Ms Contin are studied.


Number of reports submitted per year:

Zanaflex and Ms contin drug interactions.

Drug effectiveness over time:

Zanaflex:
  • < 1 month: 0.0% - (0 of 3 people)
  • 1 - 6 months: 0.0% - (0 of 6 people)
  • 6 - 12 months: 50.0% - (3 of 6 people)
  • 1 - 2 years: 11.0% - (1 of 9 people)
  • 2 - 5 years: 0.0% - (0 of 2 people)
  • 5 - 10 years: 20.0% - (1 of 5 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Ms Contin:
  • < 1 month: 20.0% - (1 of 5 people)
  • 1 - 6 months: 22.0% - (2 of 9 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 37.0% - (3 of 8 people)
  • 2 - 5 years: 50.0% - (3 of 6 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 0.0% - (0 of 2 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Zanaflex:
  • female: 22.0% - (6 of 27 people)
  • male: 0.0% - (0 of 5 people)
Ms Contin:
  • female: 35.0% - (10 of 28 people)
  • male: 0.0% - (0 of 5 people)

Drug effectiveness by age:

Zanaflex:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 33.0% - (1 of 3 people)
  • 30-39: 16.0% - (1 of 6 people)
  • 40-49: 11.0% - (1 of 9 people)
  • 50-59: 20.0% - (2 of 10 people)
  • 60+: 25.0% - (1 of 4 people)
Ms Contin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 33.0% - (1 of 3 people)
  • 30-39: 16.0% - (1 of 6 people)
  • 40-49: 30.0% - (3 of 10 people)
  • 50-59: 40.0% - (4 of 10 people)
  • 60+: 25.0% - (1 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • pneumonia
  • acute respiratory distress syndrome
  • coeliac artery compression syndrome
  • drug dependence
  • hepatic necrosis
  • hypotension
  • constipation
  • drug withdrawal syndrome
  • pulmonary oedema
  • anaemia
1 - 6 months:
  • drug dependence
  • acute respiratory distress syndrome
  • coeliac artery compression syndrome
  • hepatic necrosis
  • pneumonia
  • constipation
  • drug withdrawal syndrome
  • pulmonary oedema
  • withdrawal syndrome
  • depression
6 - 12 months:
  • drug withdrawal syndrome
  • acute respiratory distress syndrome
  • coeliac artery compression syndrome
  • drug dependence
  • hepatic necrosis
  • pneumonia
  • pulmonary oedema
  • allergic reactions
  • cardiac arrest
  • chills
1 - 2 years:
  • constipation
  • acute respiratory distress syndrome
  • coeliac artery compression syndrome
  • drug dependence
  • hepatic necrosis
  • pneumonia
  • drug withdrawal syndrome
  • pulmonary oedema
  • agitation
  • ataxia
2 - 5 years:
  • neutropenic sepsis
  • pericardial effusion
  • abdominal pain
  • anaemia
  • convulsion
  • fatigue
  • fungal sepsis
  • hypokalaemia
  • hypomagnesaemia
  • neutropenia
5 - 10 years:
  • heart rate
  • hallucinations
  • nightmare
not specified:
  • pain
  • back pain
  • anxiety
  • dyspnoea
  • asthenia
  • arthralgia
  • depression
  • intervertebral disc degeneration
  • constipation
  • hypoaesthesia

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • constipation
  • fall
  • back pain
  • drug ineffective
  • vomiting
  • depression
  • dyspnoea
  • headache
male:
  • pain
  • anxiety
  • back pain
  • asthenia
  • intervertebral disc degeneration
  • dyspnoea
  • osteonecrosis of jaw
  • arthralgia
  • depression
  • hypoaesthesia

Most common drug interactions by age *:

2-9:
  • accidental drug intake by child
  • somnolence
10-19:
  • pain
  • benign intracranial hypertension
  • depression
  • hypotension
  • muscle disorder
  • vith nerve paralysis
  • weight increased
  • asthenia
  • headache
  • lethargy
20-29:
  • depression
  • sedation
  • constipation
  • fall
  • pain
  • pulmonary embolism
  • pain in extremity
  • anxiety
  • bronchitis acute
  • carbon dioxide decreased
30-39:
  • arthralgia
  • intervertebral disc degeneration
  • pain
  • intervertebral disc protrusion
  • abdominal pain
  • constipation
  • oedema peripheral
  • drug withdrawal syndrome
  • back pain
  • fatigue
40-49:
  • pain
  • constipation
  • back pain
  • fall
  • anxiety
  • depression
  • nausea
  • headache
  • drug ineffective
  • insomnia
50-59:
  • pain
  • anxiety
  • depression
  • emotional distress
  • injury
  • discomfort
  • anhedonia
  • arthralgia
  • hypophagia
  • deformity
60+:
  • pain
  • dyspnoea
  • back pain
  • asthenia
  • anxiety
  • confusional state
  • chronic obstructive pulmonary disease
  • general physical health deterioration
  • bone disorder
  • hallucination

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Zanaflex (tizanidine hydrochloride) is often used to treat muscle spasms. Ms contin (morphine sulfate) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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