Review: taking Zantac and Xanax together


Summary

Drug interactions are reported among people who take Zantac and Xanax together. This review analyzes the effectiveness and drug interactions between Zantac and Xanax. It is created by eHealthMe based on reports of 2,990 people who take the same drugs from FDA and social media, and is updated regularly.

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Zantac

Zantac has active ingredients of ranitidine hydrochloride. It is often used in indigestion. (latest outcomes from Zantac 35,120 users)

Xanax

Xanax has active ingredients of alprazolam. It is often used in stress and anxiety. (latest outcomes from Xanax 58,024 users)

On Jul, 21, 2016

2,990 people who take Zantac, Xanax are studied.


Number of reports submitted per year:

Zantac and Xanax drug interactions.

Drug effectiveness over time:

Zantac:
  • < 1 month: 18.0% - (2 of 11 people)
  • 1 - 6 months: 27.0% - (3 of 11 people)
  • 6 - 12 months: 55.0% - (5 of 9 people)
  • 1 - 2 years: 44.0% - (4 of 9 people)
  • 2 - 5 years: 64.0% - (9 of 14 people)
  • 5 - 10 years: 45.0% - (9 of 20 people)
  • 10+ years: 57.0% - (4 of 7 people)
  • not specified: 0.0% - (0 of 0 people)
Xanax:
  • < 1 month: 46.0% - (7 of 15 people)
  • 1 - 6 months: 62.0% - (5 of 8 people)
  • 6 - 12 months: 44.0% - (4 of 9 people)
  • 1 - 2 years: 33.0% - (5 of 15 people)
  • 2 - 5 years: 25.0% - (5 of 20 people)
  • 5 - 10 years: 40.0% - (4 of 10 people)
  • 10+ years: 70.0% - (7 of 10 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Zantac:
  • female: 41.0% - (23 of 56 people)
  • male: 52.0% - (13 of 25 people)
Xanax:
  • female: 50.0% - (29 of 58 people)
  • male: 30.0% - (9 of 30 people)

Drug effectiveness by age:

Zantac:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 66.0% - (4 of 6 people)
  • 30-39: 31.0% - (7 of 22 people)
  • 40-49: 45.0% - (11 of 24 people)
  • 50-59: 37.0% - (6 of 16 people)
  • 60+: 61.0% - (8 of 13 people)
Xanax:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 66.0% - (4 of 6 people)
  • 30-39: 38.0% - (8 of 21 people)
  • 40-49: 50.0% - (13 of 26 people)
  • 50-59: 47.0% - (8 of 17 people)
  • 60+: 27.0% - (5 of 18 people)

Most common drug interactions over time *:

< 1 month:
  • dyspnoea
  • asthenia
  • generalised oedema
  • malaise
  • oedema peripheral
  • dermatitis exfoliative
  • abdominal distension
  • myocardial infarction
  • pyrexia
  • ventricular extrasystoles
1 - 6 months:
  • confusional state
  • depression
  • epistaxis
  • mental disorder
  • pulmonary embolism
  • agranulocytosis
  • anxiety
  • microcytic anaemia
  • pain
  • abscess limb
6 - 12 months:
  • dyspnoea
  • anaemia
  • chest pain
  • dehydration
  • diarrhoea
  • hypovolaemic shock
  • metabolic acidosis
  • palpitations
  • pneumonia
  • pulmonary embolism
1 - 2 years:
  • dizziness
  • hypertension
  • musculoskeletal pain
  • arthralgia
  • back pain
  • intervertebral disc disorder
  • intervertebral disc protrusion
  • loss of consciousness
  • muscle spasms
  • pain
2 - 5 years:
  • depression
  • type 2 diabetes mellitus
  • abdominal pain
  • vomiting
  • sepsis
  • cardiac failure congestive
  • cholecystitis
  • coronary artery disease
  • fracture
  • lower limb fracture
5 - 10 years:
  • cerebrovascular accident
  • myocardial infarction
  • angina pectoris
  • asthma
  • depression
  • obstructive airways disorder
  • anxiety
  • atrial fibrillation
  • anger
  • rash
10+ years:
  • diabetes mellitus
  • diabetes mellitus inadequate control
  • drug ineffective
  • type 2 diabetes mellitus
  • stomach pain
  • anxiety
  • bleeding time prolonged
  • dry skin
  • high blood cholesterol
  • increased tendency to bruise
not specified:
  • nausea
  • anxiety
  • pain
  • dyspnoea
  • fatigue
  • dizziness
  • chest pain
  • depression
  • fall
  • diarrhoea

Most common drug interactions by gender *:

female:
  • nausea
  • anxiety
  • pain
  • dyspnoea
  • fatigue
  • fall
  • dizziness
  • back pain
  • diarrhoea
  • vomiting
male:
  • chest pain
  • depression
  • anxiety
  • nausea
  • dizziness
  • dyspnoea
  • fatigue
  • headache
  • constipation
  • diarrhoea

Most common drug interactions by age *:

0-1:
  • diabetes mellitus
10-19:
  • weight increased
  • suicidal ideation
  • electrocardiogram qt prolonged
  • musculoskeletal stiffness
  • blood prolactin increased
  • depression
  • completed suicide
  • lethargy
  • overdose
  • anxiety
20-29:
  • pain
  • vomiting
  • dyspnoea
  • headache
  • nausea
  • dizziness
  • insomnia
  • anxiety
  • injury
  • pain in extremity
30-39:
  • anxiety
  • depression
  • nausea
  • headache
  • drug dependence
  • dyspnoea
  • pain
  • drug ineffective
  • arthralgia
  • drug withdrawal syndrome
40-49:
  • nausea
  • chest pain
  • anxiety
  • depression
  • dyspnoea
  • headache
  • vomiting
  • pain
  • constipation
  • fatigue
50-59:
  • nausea
  • headache
  • back pain
  • fatigue
  • fall
  • asthenia
  • pain
  • weight decreased
  • anxiety
  • dizziness
60+:
  • anxiety
  • nausea
  • dizziness
  • dyspnoea
  • fatigue
  • diarrhoea
  • pain
  • fall
  • bone disorder
  • chest pain

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Zantac (ranitidine hydrochloride) is often used to treat indigestion. Xanax (alprazolam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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