Review: taking Zofran and Zantac together


Summary

Drug interactions are reported among people who take Zofran and Zantac together. This review analyzes the effectiveness and drug interactions between Zofran and Zantac. It is created by eHealthMe based on reports of 3,770 people who take the same drugs from FDA and social media, and is updated regularly.

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Zofran

Zofran has active ingredients of ondansetron hydrochloride. It is often used in nausea. (latest outcomes from Zofran 26,888 users)

Zantac

Zantac has active ingredients of ranitidine hydrochloride. It is often used in indigestion. (latest outcomes from Zantac 39,441 users)

On Aug, 26, 2016

3,770 people who take Zofran, Zantac are studied.


Number of reports submitted per year:

Zofran and Zantac drug interactions.

Drug effectiveness over time:

Zofran:
  • < 1 month: 25.0% - (1 of 4 people)
  • 1 - 6 months: 28.0% - (2 of 7 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 66.0% - (2 of 3 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Zantac:
  • < 1 month: 0.0% - (0 of 6 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 66.0% - (2 of 3 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 50.0% - (1 of 2 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Zofran:
  • female: 35.0% - (5 of 14 people)
  • male: 50.0% - (1 of 2 people)
Zantac:
  • female: 23.0% - (3 of 13 people)
  • male: 50.0% - (1 of 2 people)

Drug effectiveness by age:

Zofran:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 1 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 50.0% - (2 of 4 people)
  • 30-39: 0.0% - (0 of 3 people)
  • 40-49: 100.0% - (2 of 2 people)
  • 50-59: 33.0% - (1 of 3 people)
  • 60+: 33.0% - (1 of 3 people)
Zantac:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 1 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 4 people)
  • 30-39: 50.0% - (1 of 2 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 33.0% - (1 of 3 people)
  • 60+: 33.0% - (1 of 3 people)

Most common drug interactions over time *:

< 1 month:
  • dyspnoea
  • nausea
  • diarrhoea
  • vomiting
  • hypotension
  • pyrexia
  • tachycardia
  • erythema
  • pneumonia
  • febrile neutropenia
1 - 6 months:
  • febrile neutropenia
  • dehydration
  • pneumonia
  • diarrhoea
  • dyspnoea
  • nausea
  • hypertension
  • mucosal inflammation
  • pyrexia
  • abdominal pain
6 - 12 months:
  • dyspnoea
  • cough
  • asthenia
  • dizziness
  • fatigue
  • feeling abnormal
  • lung disorder
  • peripheral motor neuropathy
  • red blood cell count decreased
  • respiratory tract irritation
1 - 2 years:
  • decreased appetite
  • fatigue
  • atrial septal defect
  • bundle branch block right
  • cardiac murmur
  • cardiomegaly
  • crepitations
  • cyanosis
  • drug exposure during pregnancy
  • fallot's tetralogy
2 - 5 years:
  • headache
  • depression
  • pain of skin
  • anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension
  • burning eyes
  • capillary leak syndrome
  • chronic pain
  • chronic pancreatitis
  • chronic sinusitis
  • cognitive deterioration
5 - 10 years:
  • burning eyes
  • abscess - skin
  • back pain
  • body temperature fluctuation
  • breath odor
  • breathing difficulty
  • chest tightness or pressure
  • chills
  • cough
  • fatigue
10+ years:
  • abdominal bloating
  • aphasia - primary progressive
  • apraxia
  • asthenia
  • burping
  • confusional state
  • constipation aggravated
  • cough
  • cyclic vomiting syndrome
  • death
not specified:
  • nausea
  • vomiting
  • pain
  • pyrexia
  • dyspnoea
  • anxiety
  • diarrhoea
  • dehydration
  • fatigue
  • pneumonia

Most common drug interactions by gender *:

female:
  • nausea
  • vomiting
  • dyspnoea
  • pain
  • diarrhoea
  • pyrexia
  • dehydration
  • fatigue
  • anxiety
  • back pain
male:
  • nausea
  • pyrexia
  • pain
  • vomiting
  • dyspnoea
  • pneumonia
  • diarrhoea
  • anxiety
  • fatigue
  • hypotension

Most common drug interactions by age *:

0-1:
  • abdominal distension
  • hypotension
  • respiratory failure
  • blister
  • hypertension
  • maternal drugs affecting foetus
  • multi-organ failure
  • neutropenia
  • pyrexia
  • thrombocytopenia
2-9:
  • vomiting
  • pyrexia
  • cough
  • nausea
  • diarrhoea
  • tachycardia
  • febrile neutropenia
  • somnolence
  • hypotension
  • pharyngitis
10-19:
  • vomiting
  • pyrexia
  • nausea
  • abdominal pain
  • hypotension
  • pain
  • headache
  • pancytopenia
  • febrile neutropenia
  • neutropenia
20-29:
  • pain
  • nausea
  • anxiety
  • dyspnoea
  • vomiting
  • injury
  • headache
  • pyrexia
  • febrile neutropenia
  • diarrhoea
30-39:
  • nausea
  • pain
  • vomiting
  • anaemia
  • rash
  • haemorrhoids
  • dyspnoea
  • erythema
  • ovarian cyst
  • abscess
40-49:
  • nausea
  • pain
  • dyspnoea
  • vomiting
  • pyrexia
  • anxiety
  • dehydration
  • pneumonia
  • pruritus
  • fatigue
50-59:
  • nausea
  • dyspnoea
  • pyrexia
  • vomiting
  • diarrhoea
  • fatigue
  • back pain
  • dehydration
  • pain
  • chest pain
60+:
  • nausea
  • diarrhoea
  • vomiting
  • dyspnoea
  • fatigue
  • pyrexia
  • pneumonia
  • dehydration
  • asthenia
  • pain

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Zofran (ondansetron hydrochloride) is often used to treat nausea. Zantac (ranitidine hydrochloride) is often used to treat indigestion. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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