Review: taking Zoloft and Centrum together


Summary

Drug interactions are reported among people who take Zoloft and Centrum together. This review analyzes the effectiveness and drug interactions between Zoloft and Centrum. It is created by eHealthMe based on reports of 5,664 people who take the same drugs from FDA and social media, and is updated regularly.

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Zoloft

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. (latest outcomes from Zoloft 97,228 users)

Centrum

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. (latest outcomes from Centrum 17,758 users)

On Sep, 03, 2016

5,664 people who take Zoloft, Centrum are studied.


Number of reports submitted per year:

Zoloft and Centrum drug interactions.

Drug effectiveness over time:

Zoloft:
  • < 1 month: 20.0% - (2 of 10 people)
  • 1 - 6 months: 21.0% - (7 of 33 people)
  • 6 - 12 months: 46.0% - (14 of 30 people)
  • 1 - 2 years: 50.0% - (10 of 20 people)
  • 2 - 5 years: 42.0% - (15 of 35 people)
  • 5 - 10 years: 58.0% - (18 of 31 people)
  • 10+ years: 70.0% - (17 of 24 people)
  • not specified: 50.0% - (1 of 2 people)
Centrum:
  • < 1 month: 11.0% - (1 of 9 people)
  • 1 - 6 months: 0.0% - (0 of 12 people)
  • 6 - 12 months: 6.0% - (1 of 16 people)
  • 1 - 2 years: 16.0% - (3 of 18 people)
  • 2 - 5 years: 41.0% - (10 of 24 people)
  • 5 - 10 years: 38.0% - (10 of 26 people)
  • 10+ years: 58.0% - (14 of 24 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Zoloft:
  • female: 47.0% - (67 of 141 people)
  • male: 38.0% - (17 of 44 people)
Centrum:
  • female: 31.0% - (30 of 94 people)
  • male: 25.0% - (9 of 36 people)

Drug effectiveness by age:

Zoloft:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 25.0% - (2 of 8 people)
  • 20-29: 22.0% - (5 of 22 people)
  • 30-39: 43.0% - (17 of 39 people)
  • 40-49: 58.0% - (18 of 31 people)
  • 50-59: 43.0% - (22 of 51 people)
  • 60+: 58.0% - (20 of 34 people)
Centrum:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 5 people)
  • 20-29: 18.0% - (3 of 16 people)
  • 30-39: 44.0% - (11 of 25 people)
  • 40-49: 30.0% - (6 of 20 people)
  • 50-59: 35.0% - (14 of 40 people)
  • 60+: 20.0% - (5 of 24 people)

Most common drug interactions over time *:

< 1 month:
  • atrial septal defect
  • patent ductus arteriosus
  • maternal exposure during pregnancy
  • ventricular septal defect
  • heart disease congenital
  • premature baby
  • foetal exposure during pregnancy
  • diarrhoea
  • drug exposure during pregnancy
  • transposition of the great vessels
1 - 6 months:
  • congenital anomaly
  • atrial septal defect
  • patent ductus arteriosus
  • foetal exposure during pregnancy
  • ventricular septal defect
  • premature baby
  • maternal exposure during pregnancy
  • talipes
  • heart disease congenital
  • cardiomegaly
6 - 12 months:
  • congenital anomaly
  • maternal exposure during pregnancy
  • atrial septal defect
  • ventricular septal defect
  • patent ductus arteriosus
  • foetal exposure during pregnancy
  • anomalous pulmonary venous connection
  • transposition of the great vessels
  • ear infection
  • premature baby
1 - 2 years:
  • atrial septal defect
  • maternal exposure during pregnancy
  • ventricular septal defect
  • congenital anomaly
  • patent ductus arteriosus
  • premature baby
  • foetal exposure during pregnancy
  • heart disease congenital
  • tricuspid valve incompetence
  • transposition of the great vessels
2 - 5 years:
  • atrial septal defect
  • congenital anomaly
  • maternal exposure during pregnancy
  • patent ductus arteriosus
  • foetal exposure during pregnancy
  • premature baby
  • ventricular septal defect
  • depression
  • muscle spasms
  • craniosynostosis
5 - 10 years:
  • atrial septal defect
  • maternal exposure during pregnancy
  • ventricular septal defect
  • patent ductus arteriosus
  • congenital anomaly
  • premature baby
  • pulmonary artery stenosis congenital
  • heart disease congenital
  • cardiomegaly
  • foetal exposure during pregnancy
10+ years:
  • congenital anomaly
  • depression
  • maternal exposure during pregnancy
  • foetal exposure during pregnancy
  • atrial septal defect
  • heart disease congenital
  • premature baby
  • high blood cholesterol
  • short-term memory loss
  • fallot's tetralogy
not specified:
  • atrial septal defect
  • pain
  • anxiety
  • fatigue
  • ventricular septal defect
  • nausea
  • patent ductus arteriosus
  • diarrhoea
  • depression
  • foetal exposure during pregnancy

Most common drug interactions by gender *:

female:
  • atrial septal defect
  • pain
  • nausea
  • anxiety
  • fatigue
  • depression
  • ventricular septal defect
  • patent ductus arteriosus
  • arthralgia
  • diarrhoea
male:
  • atrial septal defect
  • ventricular septal defect
  • foetal exposure during pregnancy
  • maternal exposure during pregnancy
  • patent ductus arteriosus
  • cardiomegaly
  • tricuspid valve incompetence
  • pain
  • anxiety
  • pneumonia

Most common drug interactions by age *:

0-1:
  • atrial septal defect
  • patent ductus arteriosus
  • ventricular septal defect
  • foetal exposure during pregnancy
  • heart disease congenital
  • cardiomegaly
  • congenital anomaly
  • maternal exposure during pregnancy
  • tricuspid valve incompetence
  • mitral valve incompetence
2-9:
  • cellulitis
  • cleft lip
  • cleft palate
  • conductive deafness
  • diarrhoea
  • ear infection
  • haemangioma of skin
  • nasal congestion
  • otitis media
  • pyrexia
10-19:
  • pain
  • patent ductus arteriosus
  • depression
  • nausea
  • photophobia
  • right ventricular hypertrophy
  • asthenia
  • vomiting
  • anxiety
  • motor dysfunction
20-29:
  • pain
  • anxiety
  • depression
  • atrial septal defect
  • cholecystitis chronic
  • injury
  • convulsion
  • headache
  • arthralgia
  • maternal exposure during pregnancy
30-39:
  • nausea
  • pain
  • anxiety
  • fatigue
  • headache
  • congenital anomaly
  • asthenia
  • dyspnoea
  • convulsion
  • injury
40-49:
  • pain
  • depression
  • fatigue
  • nausea
  • anxiety
  • dyspnoea
  • anaemia
  • dizziness
  • back pain
  • headache
50-59:
  • pain
  • anxiety
  • nausea
  • headache
  • fatigue
  • depression
  • osteonecrosis of jaw
  • anaemia
  • bone disorder
  • back pain
60+:
  • fall
  • pain
  • anxiety
  • diarrhoea
  • fatigue
  • asthenia
  • weight decreased
  • nausea
  • arthralgia
  • pneumonia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Zoloft (sertraline hydrochloride) is often used to treat depression. Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) is often used to treat vitamin supplementation. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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