Review: taking Zoloft and Centrum together


Summary

Drug interactions are reported among people who take Zoloft and Centrum together. This review analyzes the effectiveness and drug interactions between Zoloft and Centrum. It is created by eHealthMe based on reports of 5,096 people who take the same drugs from FDA and social media, and is updated regularly.

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Zoloft

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. (latest outcomes from Zoloft 86,060 users)

Centrum

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. (latest outcomes from Centrum 12,330 users)

On Aug, 25, 2016

5,096 people who take Zoloft, Centrum are studied.


Number of reports submitted per year:

Zoloft and Centrum drug interactions.

Drug effectiveness over time:

Zoloft:
  • < 1 month: 20.0% - (2 of 10 people)
  • 1 - 6 months: 21.0% - (7 of 33 people)
  • 6 - 12 months: 46.0% - (14 of 30 people)
  • 1 - 2 years: 50.0% - (10 of 20 people)
  • 2 - 5 years: 42.0% - (15 of 35 people)
  • 5 - 10 years: 58.0% - (18 of 31 people)
  • 10+ years: 70.0% - (17 of 24 people)
  • not specified: 50.0% - (1 of 2 people)
Centrum:
  • < 1 month: 11.0% - (1 of 9 people)
  • 1 - 6 months: 0.0% - (0 of 12 people)
  • 6 - 12 months: 6.0% - (1 of 16 people)
  • 1 - 2 years: 16.0% - (3 of 18 people)
  • 2 - 5 years: 41.0% - (10 of 24 people)
  • 5 - 10 years: 38.0% - (10 of 26 people)
  • 10+ years: 58.0% - (14 of 24 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Zoloft:
  • female: 47.0% - (67 of 141 people)
  • male: 38.0% - (17 of 44 people)
Centrum:
  • female: 31.0% - (30 of 94 people)
  • male: 25.0% - (9 of 36 people)

Drug effectiveness by age:

Zoloft:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 25.0% - (2 of 8 people)
  • 20-29: 22.0% - (5 of 22 people)
  • 30-39: 43.0% - (17 of 39 people)
  • 40-49: 58.0% - (18 of 31 people)
  • 50-59: 43.0% - (22 of 51 people)
  • 60+: 58.0% - (20 of 34 people)
Centrum:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 5 people)
  • 20-29: 18.0% - (3 of 16 people)
  • 30-39: 44.0% - (11 of 25 people)
  • 40-49: 30.0% - (6 of 20 people)
  • 50-59: 35.0% - (14 of 40 people)
  • 60+: 20.0% - (5 of 24 people)

Most common drug interactions over time *:

< 1 month:
  • patent ductus arteriosus
  • atrial septal defect
  • ventricular septal defect
  • foetal exposure during pregnancy
  • diarrhoea
  • drug exposure during pregnancy
  • heart disease congenital
  • congenital anomaly
  • drug ineffective
  • premature baby
1 - 6 months:
  • congenital anomaly
  • atrial septal defect
  • patent ductus arteriosus
  • foetal exposure during pregnancy
  • ventricular septal defect
  • premature baby
  • maternal exposure during pregnancy
  • talipes
  • cardiomegaly
  • jaundice neonatal
6 - 12 months:
  • congenital anomaly
  • maternal exposure during pregnancy
  • ventricular septal defect
  • atrial septal defect
  • patent ductus arteriosus
  • foetal exposure during pregnancy
  • anomalous pulmonary venous connection
  • ear infection
  • croup infectious
  • post procedural complication
1 - 2 years:
  • atrial septal defect
  • congenital anomaly
  • ventricular septal defect
  • patent ductus arteriosus
  • foetal exposure during pregnancy
  • premature baby
  • maternal exposure during pregnancy
  • heart disease congenital
  • tricuspid valve incompetence
  • cardiac failure congestive
2 - 5 years:
  • atrial septal defect
  • congenital anomaly
  • maternal exposure during pregnancy
  • patent ductus arteriosus
  • foetal exposure during pregnancy
  • ventricular septal defect
  • depression
  • premature baby
  • muscle spasms
  • craniosynostosis
5 - 10 years:
  • atrial septal defect
  • congenital anomaly
  • maternal exposure during pregnancy
  • ventricular septal defect
  • patent ductus arteriosus
  • premature baby
  • foetal exposure during pregnancy
  • heart disease congenital
  • pulmonary artery stenosis congenital
  • cardiomegaly
10+ years:
  • congenital anomaly
  • depression
  • foetal exposure during pregnancy
  • maternal exposure during pregnancy
  • atrial septal defect
  • premature baby
  • high blood cholesterol
  • short-term memory loss
  • fallot's tetralogy
  • headache
not specified:
  • atrial septal defect
  • pain
  • anxiety
  • fatigue
  • ventricular septal defect
  • nausea
  • patent ductus arteriosus
  • depression
  • diarrhoea
  • foetal exposure during pregnancy

Most common drug interactions by gender *:

female:
  • atrial septal defect
  • pain
  • nausea
  • anxiety
  • fatigue
  • depression
  • patent ductus arteriosus
  • arthralgia
  • ventricular septal defect
  • diarrhoea
male:
  • atrial septal defect
  • ventricular septal defect
  • foetal exposure during pregnancy
  • patent ductus arteriosus
  • cardiomegaly
  • pain
  • tricuspid valve incompetence
  • anxiety
  • maternal exposure during pregnancy
  • pneumonia

Most common drug interactions by age *:

0-1:
  • atrial septal defect
  • patent ductus arteriosus
  • ventricular septal defect
  • congenital anomaly
  • cardiomegaly
  • tricuspid valve incompetence
  • foetal exposure during pregnancy
  • mitral valve incompetence
  • maternal exposure during pregnancy
  • cardiac failure congestive
2-9:
  • cellulitis
  • cleft lip
  • cleft palate
  • conductive deafness
  • diarrhoea
  • ear infection
  • haemangioma of skin
  • nasal congestion
  • otitis media
  • pyrexia
10-19:
  • patent ductus arteriosus
  • pain
  • photophobia
  • nausea
  • right ventricular hypertrophy
  • depression
  • asthenia
  • motor dysfunction
  • visual impairment
  • atrial septal defect
20-29:
  • anxiety
  • pain
  • depression
  • cholecystitis chronic
  • convulsion
  • headache
  • injury
  • nausea
  • arthralgia
  • drug ineffective
30-39:
  • nausea
  • pain
  • fatigue
  • headache
  • congenital anomaly
  • anxiety
  • asthenia
  • convulsion
  • vomiting
  • weight decreased
40-49:
  • pain
  • depression
  • fatigue
  • anxiety
  • nausea
  • dyspnoea
  • anaemia
  • dizziness
  • osteonecrosis of jaw
  • constipation
50-59:
  • pain
  • anxiety
  • nausea
  • headache
  • fatigue
  • depression
  • osteonecrosis of jaw
  • anaemia
  • bone disorder
  • back pain
60+:
  • pain
  • fall
  • anxiety
  • diarrhoea
  • fatigue
  • weight decreased
  • asthenia
  • nausea
  • depression
  • arthralgia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Zoloft (sertraline hydrochloride) is often used to treat depression. Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) is often used to treat vitamin supplementation. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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