Review: taking Zoloft and Clonidine together


Summary

Drug interactions are reported among people who take Zoloft and Clonidine together. This review analyzes the effectiveness and drug interactions between Zoloft and Clonidine. It is created by eHealthMe based on reports of 1,562 people who take the same drugs from FDA and social media, and is updated regularly.

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Zoloft

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. (latest outcomes from Zoloft 84,365 users)

Clonidine

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. (latest outcomes from Clonidine 22,058 users)

On Aug, 23, 2016

1,562 people who take Zoloft, Clonidine are studied.


Number of reports submitted per year:

Zoloft and Clonidine drug interactions.

Drug effectiveness over time:

Zoloft:
  • < 1 month: 0.0% - (0 of 4 people)
  • 1 - 6 months: 18.0% - (3 of 16 people)
  • 6 - 12 months: 0.0% - (0 of 8 people)
  • 1 - 2 years: 66.0% - (2 of 3 people)
  • 2 - 5 years: 35.0% - (5 of 14 people)
  • 5 - 10 years: 20.0% - (1 of 5 people)
  • 10+ years: 75.0% - (6 of 8 people)
  • not specified: 0.0% - (0 of 0 people)
Clonidine:
  • < 1 month: 16.0% - (1 of 6 people)
  • 1 - 6 months: 30.0% - (3 of 10 people)
  • 6 - 12 months: 33.0% - (3 of 9 people)
  • 1 - 2 years: 40.0% - (2 of 5 people)
  • 2 - 5 years: 12.0% - (1 of 8 people)
  • 5 - 10 years: 63.0% - (7 of 11 people)
  • 10+ years: 100.0% - (2 of 2 people)
  • not specified: 33.0% - (1 of 3 people)

Drug effectiveness by gender:

Zoloft:
  • female: 29.0% - (11 of 37 people)
  • male: 28.0% - (6 of 21 people)
Clonidine:
  • female: 38.0% - (13 of 34 people)
  • male: 35.0% - (7 of 20 people)

Drug effectiveness by age:

Zoloft:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 2 people)
  • 10-19: 21.0% - (4 of 19 people)
  • 20-29: 20.0% - (1 of 5 people)
  • 30-39: 16.0% - (1 of 6 people)
  • 40-49: 50.0% - (4 of 8 people)
  • 50-59: 50.0% - (6 of 12 people)
  • 60+: 16.0% - (1 of 6 people)
Clonidine:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 2 people)
  • 10-19: 28.0% - (6 of 21 people)
  • 20-29: 0.0% - (0 of 2 people)
  • 30-39: 16.0% - (1 of 6 people)
  • 40-49: 71.0% - (5 of 7 people)
  • 50-59: 72.0% - (8 of 11 people)
  • 60+: 0.0% - (0 of 5 people)

Most common drug interactions over time *:

< 1 month:
  • vomiting
  • maternal exposure during pregnancy
  • somnolence
  • abortion spontaneous
  • nausea
  • tremor
  • anxiety
  • irritability
  • syncope
  • anger
1 - 6 months:
  • somnolence
  • memory impairment
  • vomiting
  • anxiety aggravated
  • depression aggravated
  • dizziness aggravated
  • insomnia exacerbated
  • maternal exposure during pregnancy
  • night sweats
  • vertigo
6 - 12 months:
  • aggression aggravated
  • anxiety aggravated
  • blood cholesterol increased
  • hyperlipidaemia
  • obesity
  • simple partial seizures
  • type 2 diabetes mellitus
  • anxiety
  • appetite - decreased
  • asthma aggravated
1 - 2 years:
  • nausea
  • gynaecomastia
  • mastitis
  • aggression
  • anxiety aggravated
  • blood glucose increased
  • constipation
  • depressed mood
  • diabetes mellitus insulin-dependent
  • drug ineffective
2 - 5 years:
  • dizziness
  • breast cancer female
  • breast cyst
  • postoperative wound complication
  • anxiety aggravated
  • depression aggravated
  • dizziness aggravated
  • insomnia exacerbated
  • memory impairment
  • musculoskeletal discomfort
5 - 10 years:
  • drug ineffective
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • nipple discharge - abnormal
  • simple partial seizures
  • acne cystic
  • allergies
  • angina pectoris
  • anxiety
  • appetite - decreased
  • bruxism
10+ years:
  • diabetes mellitus
  • diabetic ketoacidosis
  • pancreatitis
  • shock
  • tardive dyskinesia
  • affective disorder
  • autism spectrum disorder
  • constipation
  • convulsion
  • obsessive-compulsive disorder
not specified:
  • anxiety
  • nausea
  • pain
  • dyspnoea
  • depression
  • headache
  • dizziness
  • vomiting
  • back pain
  • fall

Most common drug interactions by gender *:

female:
  • nausea
  • pain
  • anxiety
  • depression
  • dyspnoea
  • vomiting
  • headache
  • arthralgia
  • injury
  • fall
male:
  • anxiety
  • dizziness
  • pain
  • back pain
  • headache
  • dyspnoea
  • tremor
  • nausea
  • irritability
  • diarrhoea

Most common drug interactions by age *:

0-1:
  • diabetes mellitus
  • diabetic ketoacidosis
  • pancreatitis
  • pancreatitis acute
  • shock
  • tardive dyskinesia
2-9:
  • weight increased
  • dyspnoea
  • dizziness
  • dysstasia
  • eye movement disorder
  • gastric dilatation
  • aggression
  • gastrointestinal sounds abnormal
  • attention deficit/hyperactivity disorder
  • blood pressure decreased
10-19:
  • aggression
  • anxiety
  • suicidal ideation
  • irritability
  • agitation
  • diabetic ketoacidosis
  • abnormal behaviour
  • gynaecomastia
  • hostility
  • impulsive behaviour
20-29:
  • nausea
  • anxiety
  • malaise
  • vomiting
  • abdominal pain
  • dizziness
  • cerebrovascular accident
  • headache
  • renal failure acute
  • convulsion
30-39:
  • anxiety
  • dyspnoea
  • back pain
  • headache
  • hypertension
  • nausea
  • vomiting
  • diabetes mellitus
  • hyperhidrosis
  • type 2 diabetes mellitus
40-49:
  • pain
  • anxiety
  • nausea
  • depression
  • headache
  • back pain
  • dyspnoea
  • diarrhoea
  • arthralgia
  • injury
50-59:
  • pain
  • nausea
  • oedema peripheral
  • anxiety
  • depression
  • fall
  • arthralgia
  • dyspnoea
  • anaemia
  • fatigue
60+:
  • nausea
  • hypotension
  • hypertension
  • vomiting
  • anxiety
  • diarrhoea
  • fall
  • dizziness
  • pain
  • asthenia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Zoloft (sertraline hydrochloride) is often used to treat depression. Clonidine (clonidine) is often used to treat high blood pressure. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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