Review: taking Zoloft and Clozapine together


Summary

Drug interactions are reported among people who take Zoloft and Clozapine together. This review analyzes the effectiveness and drug interactions between Zoloft and Clozapine. It is created by eHealthMe based on reports of 1,504 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone

Join a support group for people who take Zoloft and Clozapine >>>

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Zoloft

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. (latest outcomes from Zoloft 86,060 users)

Clozapine

Clozapine has active ingredients of clozapine. It is often used in schizophrenia. (latest outcomes from Clozapine 23,076 users)

On Aug, 28, 2016

1,504 people who take Zoloft, Clozapine are studied.


Number of reports submitted per year:

Zoloft and Clozapine drug interactions.

Drug effectiveness over time:

Zoloft:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 2 people)
  • 2 - 5 years: 100.0% - (3 of 3 people)
  • 5 - 10 years: 50.0% - (2 of 4 people)
  • 10+ years: 33.0% - (1 of 3 people)
  • not specified: 0.0% - (0 of 0 people)
Clozapine:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 100.0% - (2 of 2 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 40.0% - (2 of 5 people)
  • 10+ years: 66.0% - (2 of 3 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Zoloft:
  • female: 40.0% - (2 of 5 people)
  • male: 44.0% - (4 of 9 people)
Clozapine:
  • female: 60.0% - (3 of 5 people)
  • male: 44.0% - (4 of 9 people)

Drug effectiveness by age:

Zoloft:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 0.0% - (0 of 2 people)
  • 30-39: 42.0% - (3 of 7 people)
  • 40-49: 100.0% - (2 of 2 people)
  • 50-59: 50.0% - (1 of 2 people)
  • 60+: 0.0% - (0 of 0 people)
Clozapine:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 50.0% - (1 of 2 people)
  • 30-39: 42.0% - (3 of 7 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 100.0% - (2 of 2 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • lower respiratory tract infection
  • tachycardia
  • c-reactive protein increased
  • diarrhoea
  • pericardial effusion
  • fatigue
  • eosinophilia
  • pyrexia
  • asthenia
  • body temperature increased
1 - 6 months:
  • pyrexia
  • cellulitis
  • convulsion
  • obsessive-compulsive disorder
  • rash
  • skin exfoliation
  • aggression
  • granulocytopenia
  • heart rate increased
  • malaise
6 - 12 months:
  • white blood cell count decreased
  • neutropenia
  • general physical health deterioration
  • salivary hypersecretion
  • agranulocytosis
  • obsessive-compulsive disorder
  • confusional state
  • granulocytopenia
  • psychotic disorder
  • convulsion
1 - 2 years:
  • type 2 diabetes mellitus
  • death
  • granulocytopenia
  • gastrooesophageal reflux disease
  • malaise
  • blood cholesterol increased
  • catatonia
  • delusion
  • emotional distress
  • fall
2 - 5 years:
  • vomiting
  • weight decreased
  • loss of consciousness
  • overdose
  • liver function test abnormal
  • alanine aminotransferase increased
  • malaise
  • white blood cell count increased
  • pneumonia
  • cardiac arrest
5 - 10 years:
  • pneumonia
  • c-reactive protein increased
  • claudication
  • diabetes mellitus
  • diabetic coma
  • diarrhoea
  • drug detoxification
  • dyspnoea
  • femur fracture
  • lack of strength, muscle weakness, weakness
10+ years:
  • fall
  • somnolence
  • cerebrovascular accident
  • general physical health deterioration
  • lung cancer metastatic
  • eosinophil count increased
  • neutrophil count increased
  • white blood cell count increased
  • alcoholism
  • anaemia
not specified:
  • white blood cell count increased
  • antipsychotic drug level increased
  • diabetes mellitus
  • vomiting
  • tachycardia
  • white blood cell count decreased
  • neutrophil count increased
  • death
  • type 2 diabetes mellitus
  • malaise

Most common drug interactions by gender *:

female:
  • vomiting
  • tachycardia
  • antipsychotic drug level increased
  • white blood cell count decreased
  • diabetes mellitus
  • diarrhoea
  • overdose
  • liver function test abnormal
  • weight decreased
  • electrocardiogram qt prolonged
male:
  • white blood cell count increased
  • malaise
  • death
  • convulsion
  • hallucination, auditory
  • pyrexia
  • neutrophil count increased
  • white blood cell count decreased
  • psychotic disorder
  • salivary hypersecretion

Most common drug interactions by age *:

0-1:
  • cerebrovascular accident
  • muscular weakness
  • neoplasm malignant
  • tremor
2-9:
  • convulsion
  • tachycardia
  • vomiting
  • anoxic encephalopathy
  • loss of consciousness
  • cardiac arrest
  • cardio-respiratory arrest
  • hypoglycaemia
  • myocardial infarction
  • neutrophil count decreased
10-19:
  • somnolence
  • aggression
  • sedation
  • general physical health deterioration
  • anxiety
  • drug ineffective
  • homicidal ideation
  • suicidal ideation
  • abnormal behaviour
  • agitation
20-29:
  • overdose
  • vomiting
  • loss of consciousness
  • weight decreased
  • liver function test abnormal
  • tachycardia
  • antipsychotic drug level increased
  • alanine aminotransferase increased
  • electrocardiogram qt prolonged
  • chest pain
30-39:
  • diabetes mellitus
  • malaise
  • neutropenia
  • type 2 diabetes mellitus
  • white blood cell count increased
  • weight increased
  • neutrophil count increased
  • abdominal pain
  • psychotic disorder
  • diabetic ketoacidosis
40-49:
  • white blood cell count decreased
  • tachycardia
  • vomiting
  • diabetes mellitus
  • type 2 diabetes mellitus
  • platelet count decreased
  • neutropenia
  • white blood cell count increased
  • diarrhoea
  • neutrophil count decreased
50-59:
  • death
  • pneumonia
  • white blood cell count increased
  • type 2 diabetes mellitus
  • pyrexia
  • neutrophil count increased
  • granulocytopenia
  • leukopenia
  • antipsychotic drug level increased
  • diabetes mellitus
60+:
  • death
  • pyrexia
  • malaise
  • fall
  • granulocytopenia
  • fatigue
  • pneumonia
  • white blood cell count increased
  • lower respiratory tract infection
  • neutrophil count increased

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Zoloft and Clozapine?

Can you answer these questions?

More questions for: Zoloft, Clozapine

You may be interested in these reviews

More reviews for: Zoloft, Clozapine

On eHealthMe, Zoloft (sertraline hydrochloride) is often used to treat depression. Clozapine (clozapine) is often used to treat schizophrenia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.