Review: taking Zoloft and Oxycodone together


Summary

Drug interactions are reported among people who take Zoloft and Oxycodone together. This review analyzes the effectiveness and drug interactions between Zoloft and Oxycodone. It is created by eHealthMe based on reports of 3,042 people who take the same drugs from FDA and social media, and is updated regularly.

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Zoloft

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. (latest outcomes from Zoloft 84,365 users)

Oxycodone

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. (latest outcomes from Oxycodone 32,427 users)

On Aug, 19, 2016

3,042 people who take Zoloft, Oxycodone are studied.


Number of reports submitted per year:

Zoloft and Oxycodone drug interactions.

Drug effectiveness over time:

Zoloft:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 14.0% - (1 of 7 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 60.0% - (6 of 10 people)
  • 2 - 5 years: 38.0% - (5 of 13 people)
  • 5 - 10 years: 28.0% - (2 of 7 people)
  • 10+ years: 28.0% - (2 of 7 people)
  • not specified: 0.0% - (0 of 0 people)
Oxycodone:
  • < 1 month: 33.0% - (2 of 6 people)
  • 1 - 6 months: 50.0% - (6 of 12 people)
  • 6 - 12 months: 57.0% - (4 of 7 people)
  • 1 - 2 years: 40.0% - (2 of 5 people)
  • 2 - 5 years: 55.0% - (5 of 9 people)
  • 5 - 10 years: 25.0% - (2 of 8 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Zoloft:
  • female: 30.0% - (9 of 30 people)
  • male: 41.0% - (7 of 17 people)
Oxycodone:
  • female: 53.0% - (16 of 30 people)
  • male: 29.0% - (5 of 17 people)

Drug effectiveness by age:

Zoloft:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 0.0% - (0 of 5 people)
  • 30-39: 43.0% - (7 of 16 people)
  • 40-49: 33.0% - (3 of 9 people)
  • 50-59: 40.0% - (4 of 10 people)
  • 60+: 16.0% - (1 of 6 people)
Oxycodone:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 50.0% - (2 of 4 people)
  • 30-39: 55.0% - (10 of 18 people)
  • 40-49: 40.0% - (4 of 10 people)
  • 50-59: 30.0% - (3 of 10 people)
  • 60+: 50.0% - (2 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • dyspnoea
  • insomnia
  • diarrhoea
  • pain
  • respiratory disorder
  • asthenia
  • drug hypersensitivity
  • malaise
  • nausea
  • pain in extremity
1 - 6 months:
  • nausea
  • fall
  • depression
  • mental status changes
  • confusional state
  • drug dependence
  • vomiting
  • anxiety
  • pain in extremity
  • back pain
6 - 12 months:
  • anxiety
  • depression
  • drug dependence
  • insomnia
  • drug withdrawal syndrome
  • nausea
  • pain
  • drug ineffective
  • pain in extremity
  • constipation
1 - 2 years:
  • drug dependence
  • drug withdrawal syndrome
  • pain
  • insomnia
  • nausea
  • vomiting
  • anxiety
  • depression
  • hyperhidrosis
  • drug abuser
2 - 5 years:
  • depression
  • drug dependence
  • drug withdrawal syndrome
  • anxiety
  • insomnia
  • suicidal ideation
  • fall
  • pain
  • dyspnoea
  • back pain
5 - 10 years:
  • catatonia
  • depression
  • cellulitis
  • dizziness
  • gait disturbance
  • pain
  • overdose
  • pain in extremity
  • anaemia
  • atrophic vulvovaginitis
10+ years:
  • depression
  • morbid thoughts
  • tiredness
  • acute hepatic failure
  • asthenia
  • congenital anomaly
  • constipation
  • fatigue
  • headache
  • left ventricular hypertrophy
not specified:
  • pain
  • anxiety
  • nausea
  • back pain
  • depression
  • dyspnoea
  • asthenia
  • fall
  • arthralgia
  • vomiting

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • nausea
  • depression
  • back pain
  • vomiting
  • pain in extremity
  • arthralgia
  • fall
  • injury
male:
  • pain
  • anxiety
  • back pain
  • depression
  • nausea
  • dyspnoea
  • asthenia
  • fall
  • osteonecrosis of jaw
  • fatigue

Most common drug interactions by age *:

0-1:
  • congenital nail disorder
  • nipple disorder
  • eye discharge
  • facial dysmorphism
  • fever neonatal
  • maternal drugs affecting foetus
  • premature baby
  • acromegaly
  • anomaly of orbit, congenital
  • congenital anomaly
2-9:
  • hypertension
  • foetal exposure during pregnancy
  • premature baby
  • abdominal distension
  • abdominal pain
  • abnormal behaviour
  • acrochordon
  • amnesia
  • anaemia
  • animal bite
10-19:
  • pain
  • nausea
  • pyrexia
  • anxiety
  • drug withdrawal syndrome
  • vomiting
  • chills
  • abdominal pain
  • contusion
  • cough
20-29:
  • pain
  • nausea
  • anxiety
  • depression
  • emotional distress
  • insomnia
  • deep vein thrombosis
  • hypoaesthesia
  • diarrhoea
  • drug abuse
30-39:
  • anxiety
  • depression
  • nausea
  • asthenia
  • drug dependence
  • pain
  • drug withdrawal syndrome
  • headache
  • weight decreased
  • hypoaesthesia
40-49:
  • pain
  • depression
  • nausea
  • anxiety
  • back pain
  • headache
  • constipation
  • drug dependence
  • chest pain
  • arthralgia
50-59:
  • pain
  • anxiety
  • nausea
  • depression
  • dyspnoea
  • vomiting
  • fatigue
  • back pain
  • weight decreased
  • anaemia
60+:
  • pain
  • anxiety
  • back pain
  • fall
  • osteonecrosis of jaw
  • asthenia
  • osteomyelitis
  • dyspnoea
  • pneumonia
  • bone disorder

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Zoloft (sertraline hydrochloride) is often used to treat depression. Oxycodone (oxycodone hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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