Review: taking Zoloft and Prednisone together


Summary

Drug interactions are reported among people who take Zoloft and Prednisone together. This review analyzes the effectiveness and drug interactions between Zoloft and Prednisone. It is created by eHealthMe based on reports of 6,467 people who take the same drugs from FDA and social media, and is updated regularly.

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Zoloft

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. (latest outcomes from Zoloft 97,230 users)

Prednisone

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. (latest outcomes from Prednisone 224,218 users)

On Sep, 16, 2016

6,467 people who take Zoloft, Prednisone are studied.


Number of reports submitted per year:

Zoloft and Prednisone drug interactions.

Drug effectiveness over time:

Zoloft:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 22.0% - (4 of 18 people)
  • 6 - 12 months: 25.0% - (2 of 8 people)
  • 1 - 2 years: 57.0% - (8 of 14 people)
  • 2 - 5 years: 25.0% - (3 of 12 people)
  • 5 - 10 years: 70.0% - (7 of 10 people)
  • 10+ years: 66.0% - (8 of 12 people)
  • not specified: 100.0% - (1 of 1 people)
Prednisone:
  • < 1 month: 50.0% - (9 of 18 people)
  • 1 - 6 months: 35.0% - (5 of 14 people)
  • 6 - 12 months: 42.0% - (3 of 7 people)
  • 1 - 2 years: 63.0% - (7 of 11 people)
  • 2 - 5 years: 75.0% - (3 of 4 people)
  • 5 - 10 years: 80.0% - (4 of 5 people)
  • 10+ years: 33.0% - (2 of 6 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Zoloft:
  • female: 43.0% - (26 of 60 people)
  • male: 43.0% - (7 of 16 people)
Prednisone:
  • female: 51.0% - (28 of 54 people)
  • male: 50.0% - (6 of 12 people)

Drug effectiveness by age:

Zoloft:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 33.0% - (3 of 9 people)
  • 30-39: 42.0% - (6 of 14 people)
  • 40-49: 46.0% - (6 of 13 people)
  • 50-59: 52.0% - (10 of 19 people)
  • 60+: 35.0% - (7 of 20 people)
Prednisone:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 62.0% - (5 of 8 people)
  • 30-39: 33.0% - (4 of 12 people)
  • 40-49: 54.0% - (6 of 11 people)
  • 50-59: 47.0% - (8 of 17 people)
  • 60+: 61.0% - (11 of 18 people)

Most common drug interactions over time *:

< 1 month:
  • gastroenteritis viral
  • vomiting
  • headache
  • fluid overload
  • nausea
  • pregnancy
  • crohn's disease
  • diarrhoea
  • premature delivery
  • pyrexia
1 - 6 months:
  • fatigue
  • blood glucose increased
  • sudden cardiac death
  • arthralgia
  • asthenia
  • mastocytosis
  • pulmonary embolism
  • dehydration
  • drug ineffective
  • dyspnoea
6 - 12 months:
  • hypertension
  • chronic myelomonocytic leukaemia
  • blood glucose increased
  • depression
  • foetal exposure during pregnancy
  • pain
  • anxiety
  • drug ineffective
  • fall
  • hyperglycaemia
1 - 2 years:
  • pulmonary embolism
  • congenital anomaly
  • hypertension
  • weight decreased
  • depression
  • dizziness (excl vertigo)
  • drug ineffective
  • fatigue
  • gait disturbance
  • vision blurred
2 - 5 years:
  • depression
  • dizziness
  • fibrocystic breast disease
  • fall
  • osteonecrosis
  • pain
  • dyspnoea
  • foetal exposure during pregnancy
  • musculoskeletal pain
  • overdose
5 - 10 years:
  • vasovagal attack
  • muscle stiffness
  • muscle twitching
  • palpitations
  • tiredness
  • weakness
  • anger
  • atrial septal defect
  • cardiac failure congestive
  • cellulitis
10+ years:
  • depression
  • osteomyelitis
  • dizziness
  • drug hypersensitivity
  • osteonecrosis
  • arthropathy
  • chronic obstructive pulmonary disease
  • diarrhoea
  • hyperkeratosis
  • nephrogenic systemic fibrosis
not specified:
  • pain
  • anxiety
  • nausea
  • fatigue
  • dyspnoea
  • fall
  • asthenia
  • headache
  • pneumonia
  • arthralgia

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • anxiety
  • arthralgia
  • fatigue
  • fall
  • dyspnoea
  • headache
  • diarrhoea
  • asthenia
male:
  • pain
  • anxiety
  • asthenia
  • dyspnoea
  • pneumonia
  • nausea
  • osteonecrosis of jaw
  • fatigue
  • headache
  • depression

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • premature baby
  • blood cholesterol increased
  • gallbladder operation
  • sensation of foreign body
  • type 2 diabetes mellitus
  • anomaly of external ear congenital
  • aortic valve atresia
  • atrial septal defect
  • breast cancer
2-9:
  • foetal exposure during pregnancy
  • premature baby
  • low birth weight baby
  • abdominal pain
  • hypertension
  • hypokalaemia
  • pyrexia
  • skin exfoliation
  • abdominal distension
  • abnormal behaviour
10-19:
  • fatigue
  • abdominal distension
  • crohn's disease
  • hallucination, auditory
  • abdominal pain
  • pyrexia
  • injection site pain
  • pain
  • alopecia
  • myopathy
20-29:
  • crohn's disease
  • anxiety
  • back pain
  • diarrhoea
  • depression
  • fatigue
  • insomnia
  • nausea
  • urinary tract infection
  • anaemia
30-39:
  • pain
  • headache
  • fatigue
  • pulmonary embolism
  • dyspnoea
  • anxiety
  • nausea
  • drug ineffective
  • dizziness
  • pain in extremity
40-49:
  • pain
  • headache
  • nausea
  • fatigue
  • anxiety
  • arthralgia
  • dyspnoea
  • diarrhoea
  • depression
  • drug ineffective
50-59:
  • pain
  • nausea
  • anxiety
  • pyrexia
  • fatigue
  • headache
  • dyspnoea
  • arthralgia
  • depression
  • oedema peripheral
60+:
  • pain
  • fall
  • anxiety
  • asthenia
  • dyspnoea
  • nausea
  • pneumonia
  • back pain
  • fatigue
  • arthralgia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Zoloft (sertraline hydrochloride) is often used to treat depression. Prednisone (prednisone) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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