Review: taking Zoloft and Tylenol together


Summary

Drug interactions are reported among people who take Zoloft and Tylenol together. This review analyzes the effectiveness and drug interactions between Zoloft and Tylenol. It is created by eHealthMe based on reports of 6,348 people who take the same drugs from FDA and social media, and is updated regularly.

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Zoloft

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. (latest outcomes from Zoloft 97,228 users)

Tylenol

Tylenol has active ingredients of acetaminophen. It is often used in pain. (latest outcomes from Tylenol 81,872 users)

On Sep, 19, 2016

6,348 people who take Zoloft, Tylenol are studied.


Number of reports submitted per year:

Zoloft and Tylenol drug interactions.

Drug effectiveness over time:

Zoloft:
  • < 1 month: 0.0% - (0 of 8 people)
  • 1 - 6 months: 22.0% - (5 of 22 people)
  • 6 - 12 months: 0.0% - (0 of 6 people)
  • 1 - 2 years: 25.0% - (4 of 16 people)
  • 2 - 5 years: 56.0% - (9 of 16 people)
  • 5 - 10 years: 44.0% - (4 of 9 people)
  • 10+ years: 66.0% - (4 of 6 people)
  • not specified: 0.0% - (0 of 0 people)
Tylenol:
  • < 1 month: 33.0% - (5 of 15 people)
  • 1 - 6 months: 33.0% - (2 of 6 people)
  • 6 - 12 months: 22.0% - (2 of 9 people)
  • 1 - 2 years: 28.0% - (2 of 7 people)
  • 2 - 5 years: 15.0% - (2 of 13 people)
  • 5 - 10 years: 50.0% - (6 of 12 people)
  • 10+ years: 16.0% - (1 of 6 people)
  • not specified: 0.0% - (0 of 2 people)

Drug effectiveness by gender:

Zoloft:
  • female: 30.0% - (18 of 59 people)
  • male: 33.0% - (8 of 24 people)
Tylenol:
  • female: 28.0% - (15 of 52 people)
  • male: 26.0% - (5 of 19 people)

Drug effectiveness by age:

Zoloft:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 6 people)
  • 20-29: 31.0% - (5 of 16 people)
  • 30-39: 22.0% - (4 of 18 people)
  • 40-49: 41.0% - (7 of 17 people)
  • 50-59: 31.0% - (5 of 16 people)
  • 60+: 50.0% - (5 of 10 people)
Tylenol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 40.0% - (2 of 5 people)
  • 20-29: 30.0% - (4 of 13 people)
  • 30-39: 29.0% - (5 of 17 people)
  • 40-49: 7.0% - (1 of 14 people)
  • 50-59: 40.0% - (6 of 15 people)
  • 60+: 28.0% - (2 of 7 people)

Most common drug interactions over time *:

< 1 month:
  • nausea
  • vomiting
  • headache
  • confusional state
  • dehydration
  • somnolence
  • fatigue
  • anaemia
  • hyponatraemia
  • tremor
1 - 6 months:
  • congenital anomaly
  • foetal exposure during pregnancy
  • suicide attempt
  • talipes
  • completed suicide
  • intentional overdose
  • patent ductus arteriosus
  • atrial septal defect
  • maternal exposure during pregnancy
  • heart disease congenital
6 - 12 months:
  • congenital anomaly
  • atrial septal defect
  • maternal exposure during pregnancy
  • patent ductus arteriosus
  • foetal exposure during pregnancy
  • ventricular septal defect
  • premature baby
  • talipes
  • fatigue
  • heart disease congenital
1 - 2 years:
  • atrial septal defect
  • fall
  • pain
  • pain in extremity
  • congenital anomaly
  • insomnia
  • patent ductus arteriosus
  • erectile dysfunction
  • maternal exposure during pregnancy
  • ventricular septal defect
2 - 5 years:
  • congenital anomaly
  • atrial septal defect
  • maternal exposure during pregnancy
  • foetal exposure during pregnancy
  • patent ductus arteriosus
  • cardiac failure congestive
  • depression
  • headache
  • premature baby
  • sleep apnoea syndrome
5 - 10 years:
  • atrial septal defect
  • patent ductus arteriosus
  • congenital anomaly
  • ventricular septal defect
  • hypothermia
  • maternal exposure during pregnancy
  • premature baby
  • foetal exposure during pregnancy
  • heart disease congenital
  • pulmonary artery stenosis congenital
10+ years:
  • congenital anomaly
  • foetal exposure during pregnancy
  • dizziness
  • fallot's tetralogy
  • maternal exposure during pregnancy
  • pulmonary valve incompetence
  • cardiac disorder
  • chest pain
  • heart disease congenital
  • muscle cramps
not specified:
  • pain
  • nausea
  • fatigue
  • anxiety
  • depression
  • fall
  • dyspnoea
  • headache
  • asthenia
  • diarrhoea

Most common drug interactions by gender *:

female:
  • nausea
  • pain
  • fatigue
  • anxiety
  • fall
  • depression
  • headache
  • dyspnoea
  • asthenia
  • diarrhoea
male:
  • fatigue
  • pain
  • nausea
  • anxiety
  • depression
  • headache
  • back pain
  • dyspnoea
  • atrial septal defect
  • fall

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • atrial septal defect
  • patent ductus arteriosus
  • cleft palate
  • congenital anomaly
  • tricuspid valve incompetence
  • cognitive disorder
  • heart disease congenital
  • right ventricular hypertrophy
  • upper respiratory tract infection
2-9:
  • atrial septal defect
  • patent ductus arteriosus
  • craniosynostosis
  • intracranial pressure increased
  • maternal exposure during pregnancy
  • serotonin syndrome
  • speech disorder
  • cleft lip and palate
  • failure to thrive
  • holoprosencephaly
10-19:
  • suicide attempt
  • vomiting
  • pain
  • nausea
  • suicidal ideation
  • depression
  • blood triglycerides increased
  • epistaxis
  • inflammatory bowel disease
  • irritable bowel syndrome
20-29:
  • pain
  • nausea
  • headache
  • fatigue
  • anxiety
  • pulmonary embolism
  • vomiting
  • depression
  • deep vein thrombosis
  • injury
30-39:
  • nausea
  • headache
  • anxiety
  • asthenia
  • pain
  • dizziness
  • depression
  • urinary tract infection
  • fatigue
  • weight decreased
40-49:
  • pain
  • nausea
  • fatigue
  • anxiety
  • depression
  • diarrhoea
  • pain in extremity
  • headache
  • back pain
  • dyspnoea
50-59:
  • pain
  • nausea
  • anxiety
  • depression
  • headache
  • fatigue
  • anaemia
  • dyspnoea
  • fall
  • abdominal pain
60+:
  • fatigue
  • nausea
  • fall
  • pain
  • anxiety
  • pneumonia
  • dyspnoea
  • asthenia
  • diarrhoea
  • headache

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Zoloft (sertraline hydrochloride) is often used to treat depression. Tylenol (acetaminophen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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